<abstract xmlns="http://www.w3.org/1999/xhtml"><sec id="j_1905-7415.0901.366_s_101_w2aab3b7b6b1b6b1aab1c16b1Aa"><h3>Background</h3><p>Cartilage degeneration is considered as the initial defect in osteoarthritis. Measurement of cartilage volume is important to monitor disease progression and therapeutic response.</p></sec><sec id="j_1905-7415.0901.366_s_102_w2aab3b7b6b1b6b1aab1c16b2Aa"><h3>Objectives</h3><p>To measure tibial cartilage volume using magnetic resonance imaging (MRI), and to evaluate the accuracy and interobserver reliability of tibial cartilage volume measurement using MRI.</p></sec><sec id="j_1905-7415.0901.366_s_103_w2aab3b7b6b1b6b1aab1c16b3Aa"><h3>Methods</h3><p>The outline boundaries of the medial and lateral tibial cartilage were drawn manually on 1 mm slices using a track-ball to calculate the volume of each slice. Total calculated MRI-derived tibial cartilage volume was determined by summation of the slice volumes. The calculated tibial cartilage volume was compared to the actual tibial cartilage volume.</p></sec><sec id="j_1905-7415.0901.366_s_104_w2aab3b7b6b1b6b1aab1c16b4Aa"><h3>Results</h3><p>There was a strong correlation between the calculated and actual tibial cartilage volumes determined by a radiologist and a researcher (98% and 89% agreement in medial tibial cartilage, 99% and 97% agreement in lateral tibial cartilage, respectively). High observer reliability was identified (92% agreement in medial tibial cartilage and 97% agreement in lateral tibial cartilage).</p></sec><sec id="j_1905-7415.0901.366_s_105_w2aab3b7b6b1b6b1aab1c16b5Aa"><h3>Conclusion</h3><p>Tibial cartilage volume measurement using MRI can be easily performed by well-trained personnel such as radiologists or residents, and can be used to estimate tibial cartilage volume preoperatively in total knee arthroplasty, and to monitor disease progression and response to therapy.</p></sec></abstract>

BackgroundCartilage degeneration is considered as the initial defect in osteoarthritis. Measurement of cartilage volume is important to monitor disease progression and therapeutic response.ObjectivesTo measure tibial cartilage volume using magnetic resonance imaging (MRI), and to evaluate the accuracy and interobserver reliability of tibial cartilage volume measurement using MRI.MethodsThe outline boundaries of the medial and lateral tibial cartilage were drawn manually on 1 mm slices using a track-ball to calculate the volume of each slice. Total calculated MRI-derived tibial cartilage volume was determined by summation of the slice volumes. The calculated tibial cartilage volume was compared to the actual tibial cartilage volume.ResultsThere was a strong correlation between the calculated and actual tibial cartilage volumes determined by a radiologist and a researcher (98% and 89% agreement in medial tibial cartilage, 99% and 97% agreement in lateral tibial cartilage, respectively). High observer reliability was identified (92% agreement in medial tibial cartilage and 97% agreement in lateral tibial cartilage).ConclusionTibial cartilage volume measurement using MRI can be easily performed by well-trained personnel such as radiologists or residents, and can be used to estimate tibial cartilage volume preoperatively in total knee arthroplasty, and to monitor disease progression and response to therapy.

Tibial cartilage volume measurement in knee osteoarthritis using magnetic resonance imaging

Department of Radiology, Faculty of Medicine

Asian Biomedicine

This work is licensed under the Creative Commons Attribution-NonCommercial-NoDerivatives 3.0 License.

BackgroundCartilage degeneration is considered as the initial defect in osteoarthritis. Measurement of cartilage volume is important to monitor disease...

Volume (cm³)	Minimum	Maximum	Mean	SD	CV%
Medial tibia
Radiologist	0.29	1.63	1.13	0.32	28.13
Researcher	0.29	1.77	1.10	0.34	31.02
Actual volume	0.30	1.72	1.14	0.35	30.23
Lateral tibia
Radiologist	0.77	3.17	1.84	0.55	30.22
Researcher	0.60	3.24	1.78	0.57	31.91
Actual volume	0.65	3.2	1.85	0.58	31.44

Characteristic	Mean	Range
Age (y)	70.7	58–85
Body weight (kg)	69.2	53–92
Height (cm)	153.7	143–162
Body mass index (kg/cm²)	29.3	21.6–35.9

Tibial cartilage volume measurement in knee osteoarthritis using magnetic resonance imaging

Article Category: Original article

Published Online: Jan 31, 2017

Page range: 41 - 47

DOI: https://doi.org/10.5372/1905-7415.0901.366

Keywords
magnetic resonance imaging, MRI, measurement, tibial cartilage volume

© 2017 Varalee Vanichtantikul, Sarit Hongvilai, Numphung Numkarunarunrote

This work is licensed under the Creative Commons Attribution-NonCommercial-NoDerivatives 3.0 License.

Figure 1

Figure 2

Figure 3

Figure 4

Precision of magnetic resonance imaging-based analysis of tibial cartilage in osteoarthritis

Basic characteristics of 22 patient participants

Tibial cartilage volume measurement in knee osteoarthritis using magnetic resonance imaging

Article Category: Original article

Published Online: Jan 31, 2017

Page range: 41 - 47

DOI: https://doi.org/10.5372/1905-7415.0901.366

Keywordsmagnetic resonance imaging, MRI, measurement, tibial cartilage volume

© 2017 Varalee Vanichtantikul, Sarit Hongvilai, Numphung Numkarunarunrote

This work is licensed under the Creative Commons Attribution-NonCommercial-NoDerivatives 3.0 License.

Figure 1

Figure 2

Figure 3

Figure 4

Precision of magnetic resonance imaging-based analysis of tibial cartilage in osteoarthritis

Basic characteristics of 22 patient participants

Keywords
magnetic resonance imaging, MRI, measurement, tibial cartilage volume