Phase I study of integrating PET/CT and dose-escalated intensity modulated radiation therapy using a simultaneous integrated boost technique for thoracic esophageal cancer

1. Urba SG, Orringer MB, Turrisi A, Iannettoni M, Forastiere A, Strawderman M. Randomized trial of preoperative chemoradiation versus surgery alone in patients with locoregional esophageal carcinoma. J Clin Oncol. 2001; 19:305-13.10.1200/JCO.2001.19.2.30511208820Search in Google Scholar

2. Bosset JF, Gignoux M, Triboulet JP, Tiret E, Mantion G, Elias D, et al. Chemoradiotherapy followed by surgery compared with surgery alone in squamouscell cancer of the esophagus. N Engl J Med. 1997; 337: 161-7.10.1056/NEJM1997071733703049219702Search in Google Scholar

3. Herskovic A, Martz K, al-Sarraf M, Leichman L, Brindle J, Vaitkevicius V, et al. Combined chemotherapy and radiotherapy compared with radiotherapy alone in patients with cancer of the esophagus. N Engl J Med. 1992; 326:1593-8.10.1056/NEJM1992061132624031584260Search in Google Scholar

4. Kim TJ, Kim HY, Lee KW, Kim MS. Multimodality assessment of esophageal cancer: preoperative staging and monitoring of response to therapy. Radio Graphics. 2009; 29:403-21.10.1148/rg.29208510619325056Search in Google Scholar

5. Westerterp M, van Westreenen HL, Reitsma JB, Hoekstra OS, Stoker J, Fockens P, et al. Esophageal cancer: CT, endoscopic US, and FDG PET for assessment of response to neoadjuvant therapy- systematic review. Radiology. 2005; 236:841-51.10.1148/radiol.236304104216118165Search in Google Scholar

6. Weber WA, Ott K, Becker K, Dittler HJ, Helmberger H, Avril NE, et al. Prediction of response to preoperative chemotherapy in adenocarcinomas of the esophagogastric junction by metabolic imaging. J Clin Oncol. 2001; 12:3058-65.10.1200/JCO.2001.19.12.305811408502Search in Google Scholar

7. Br cher BL, Weber W, Bauer M, Fink U, Avril N, Stein HJ, et al. Neoadjuvant therapy of esophageal squamous cell carcinoma: Response evaluation by positron emission tomography. Ann Surg. 2001; 3: 300-9.10.1097/00000658-200103000-00002142124411224616Search in Google Scholar

8. Song SY, Kim JH, Ryu JS, Lee GH, Kim SB, Park SI, et al. FDG-PET in the prediction of pathologic response after neoadjuvant chemoradiotherapy in locally advanced, resectable esophageal cancer. Int J Radiat Oncol Biol Phys. 2005; 4:1053-9.10.1016/j.ijrobp.2005.03.03315964705Open DOISearch in Google Scholar

9. Zhong X, Yu J, Zhang B, Mu D, Zhang W, Li D, et al. Using 18F-fluorodeoxyglucose positron emission tomography to estimate the length of gross tumor in patients with squamous cell carcinoma of the esophagus. Int J Radiat Oncol Biol Phys. 2009; 73: 136-41.10.1016/j.ijrobp.2008.04.01518538492Open DOISearch in Google Scholar

10. Han D, Yu J, Yu Y, Zhang G, Zhong X, Lu J, et al. Comparison of (18)F-fluorothymidine and (18)Ffluorodeoxyglucose PET/CT in delineating gross tumor volume by optimal threshold in patients with squamous cell carcinoma of thoracic esophagus. Int J Radiat Oncol Biol Phys. 2010; 15;76:1235-41.10.1016/j.ijrobp.2009.07.168119910143Open DOISearch in Google Scholar

11. Chandra A, Guerrero TM, Liu HH, Tucker SL, Liao Z, Wang X, et al. Feasibility of using intensity-modulated radiotherapy to improve lung sparing in treatment planning for distal esophageal cancer. Radiother Oncol. 2005; 77:247-53.10.1016/j.radonc.2005.10.017Open DOISearch in Google Scholar

12. Chen YJ, Liu A, Han C, Tsai PT, Schultheiss TE, Pezner RD, et al. Helical tomotherapy for radiotherapy in esophageal cancer: a preferred plan with better conformal target coverage and more homogeneous dose distribution. Med Dosim. 2007; 32:166-71.10.1016/j.meddos.2006.12.003Open DOISearch in Google Scholar

13. La TH, Minn AY, Su Z, Fisher GA, Ford JM, Kunz P, et al. Multimodality treatment with intensity modulated radiation therapy for esophageal cancer. Dis Esophagus. 2010; 23;300-8.10.1111/j.1442-2050.2009.01004.xOpen DOISearch in Google Scholar

14. Wu VW, Sham JS, Kwong DL. Inverse planning in three-dimensional conformal and intensity-modulated radiotherapy of mid-thoracic oesophageal cancer. Br J Radiol. 2004; 77:568-72.10.1259/bjr/19972578Open DOISearch in Google Scholar

15. Nutting CM, Bedford JL, Cosgrove VP, Tait DM, Dearnaley DP, Webb S. A comparison of conformal and intensity-modulated techniques for oesophageal radiotherapy. Radiother Oncol. 2001; 61:157-63.10.1016/S0167-8140(01)00438-8Open DOISearch in Google Scholar

16. Hsu FM, Lee YC, Lee JM, Hsu CH, Lin CC, Tsai YC, et al. Association of clinical and dosimetric factors with postoperative pulmonary complications in esophageal cancer patients receiving intensitymodulated radiation therapy and concurrent chemotherapy followed by thoracic esophagectomy. Ann Surg Oncol. 2009; 16:1669-77.10.1245/s10434-009-0401-019267157Open DOISearch in Google Scholar

17. Wang SL, Liao Z, Liu H, Ajani J, Swisher S, Cox JD, et al. Intensity-modulated radiation therapy with concurrent chemotherapy for locally advanced cervical and upper thoracic esophageal cancer. World J Gastroenterol. 2006; 12:5501-8.10.3748/wjg.v12.i34.5501408823317006988Open DOISearch in Google Scholar

18. American Joint Committee on Cancer. Esophagus, 6th ed. New York: Springer Verlag. 2002.Search in Google Scholar

19. Cancer Therapy Evaluation Program. Common Terminology Criteria for Adverse Events, Version 3.0, DCTD, NCI, NIH, DHHS March 31, 2003 (http://ctep.cancer.gov: August 9, 2006 http://ctep.cancer.gov/forms/CTCAEv3.pdf. Accessed 1 August 2009.Search in Google Scholar

20. Wahl RL, Jacene H, Kasamon Y, Lodge MA. From RECIST to PERCIST: Evolving considerations for PET response criteria in solid tumors. J Nucl Med. 2009; 50:122S-50S.10.2967/jnumed.108.057307275524519403881Open DOISearch in Google Scholar

21. Levine EA, Farmer MR, Clark P, Mishra G, Ho C, Geisinger KR, et al. Predictive value of 18-fluorodeoxy- glucose-positron emission tomography (18FFDG- PET) in the identification of responders to chemoradiation therapy for the treatment of locally advanced esophageal cancer. Ann Surg. 2006; 243: 472-8.10.1097/01.sla.0000208430.07050.61144895316552197Open DOISearch in Google Scholar

22. Swisher SG, Erasmus J, Maish M, Correa AM, Macapinlac H, Ajani JA, et al. 2-Fluoro-2-deoxy-Dglucose positron emission tomography imaging is predictive of pathologic response and survival after preoperative chemoradiation in patients with esophageal carcinoma. Cancer. 2004; 101:1776-85.10.1002/cncr.2058515386332Open DOISearch in Google Scholar

23. Cooper JS, Guo MD, Herskovic A, Macdonald JS, Martenson JA Jr, Al-Sarraf M, et al. Chemoradiotherapy of locally advanced esophageal cancer: long-term follow-up of a prospective randomized trial (RTOG 85-01). Radiation Therapy Oncology Group. JAMA. 1999; 281:1623-7.Search in Google Scholar

24. Minsky BD, Pajak TF, Ginsberg RJ, Pisansky TM, Martenson J, Komaki R, et al. INT 0123 (Radiation Therapy Oncology Group 94-05) phase III trial of combined-modality therapy for esophageal cancer: high-dose versus standard-dose radiation therapy. J Clin Oncol. 2002; 20:1167-74.10.1200/JCO.2002.20.5.1167Search in Google Scholar

25. Bedenne L, Michel P, Bouch_ O, Milan C, Mariette C, Conroy T, et al. Chemoradiation followed by surgery compared with chemoradiation alone in squamous cancer of the esophagus: FFCD 9102. J Clin Oncol. 2007; 25:1160-8.10.1200/JCO.2005.04.7118Open DOISearch in Google Scholar

26. Stahl M, Stuschke M, Lehmann N, Meyer HJ, Walz MK, Seeber S, et al. Chemoradiation with and without surgery in patients with locally advanced squamous cell carcinoma of the esophagus. J Clin Oncol. 2005; 23:2310-7.10.1200/JCO.2005.00.034Open DOISearch in Google Scholar

27. Walsh TN, Noonan N, Hollywood D, Kelly A, Keeling N, Hennessy TP. A comparison of multimodal therapy and surgery for esophageal adenocarcinoma. N Engl J Med. 1996; 335:462-7.10.1056/NEJM199608153350702Search in Google Scholar

28. Tepper J, Krasna MJ, Niedzwiecki D, Hollis D, Reed CE, Goldberg R, et al. Phase III trial of trimodality therapy with cisplatin, fluorouracil, radiotherapy, and surgery compared with surgery alone for esophageal cancer: CALGB 9781. J Clin Oncol. 2008; 26:1086-92.10.1200/JCO.2007.12.9593Open DOISearch in Google Scholar

29. Burmeister BH, Smithers BM, Gebski V, Fitzgerald L, Simes RJ, Devitt P, et al. Surgery alone versus chemoradiotherapy followed by surgeray for resectable cancer of the oesophagus: a randomized controlled phase III trial. Lancet Oncol. 2005; 6:659-68.10.1016/S1470-2045(05)70288-6Open DOISearch in Google Scholar

30. Le Prise E, Etienne PL, Meunier B, Maddern G, Ben Hassel M, Gedouin D, et al. A randomized study of chemotherapy, radiation therapy, and surgery versus surgery for localized squamous cell carcinoma of the esophagus. Cancer. 1994; 73:1779-84.10.1002/1097-0142(19940401)73:7<1779::AID-CNCR2820730702>3.0.CO;2-TOpen DOISearch in Google Scholar

31. Nygaard K, Hagen S, Hansen HS, Hatlevoll R, Hultborn R, Jakobsen A, et al. Pre-operative radiotherapy prolongs survival in operable esophageal carcinoma: a randomized, multicenter study of preoperative radiotherapy and chemotherapy. The second Scandinavian trial in esophageal cancer. World J Surg. 1992; 16:1104-9.10.1007/BF02067069Open DOISearch in Google Scholar

32. Apinop C, Puttisak P, Preecha N. A prospective study of combined therapy in esophageal cancer. Hepatogastroenterology. 1994; 41:391-3.Search in Google Scholar

33. Welsh J, Palmer MB, Ajani JA, Liao Z, Swisher SG, Hofstetter WL, et al. Esophageal cancer dose escalation using a simultaneous integrated boost technique. Int J Radiat Oncol Biol Phys. doi:10.1016/j.ijrobp.2010. 10.023.Search in Google Scholar

34. Shi A, Zhu G, Wu H, Yu R, Li F, Xu B. Analysis of clinical and dosimetric factors associated with severe acute radiation pneumonitis in patients with locally advanced non-small cell lung cancer treated with concurrent chemotherapy and intensity-modulated radiotherapy. Radiat Oncol. 2010; 5:35.10.1186/1748-717X-5-35Open DOISearch in Google Scholar

35. Flamen P, Van Cutsem E, Lerut A, Cambier JP, Haustermans K, Bormans G, et al. Positron emission tomography for assessment of the response to induction radiochemotherapy in locally advanced oesophageal cancer. Ann Oncol. 2002; 3:361-8.10.1093/annonc/mdf08111996465Open DOISearch in Google Scholar