<abstract xmlns="http://www.w3.org/1999/xhtml"><p>In the present study we have determined some characteristics (aspect, odor, solubility, emulsion type, water and volatile substances content, total fatty matter, saponification index, ester index) for three pharmaceutical ointments belonging to the group of non-steroidal anti-inflammatory: Diclac, Ketonal, Indometacin and one antibiotic ointment for ophthalmic use: Ophtagram. In order to achieve stability study of studied ointments, the pH, the acidity index, the peroxide index and the iodine index were determined over a year every three months. After 9 months from the opening of the tubes, analytical determinations have shown that pH values, acidity, peroxide and iodine indexes no longer fit to the values recommended for medical use, which confirms the directions available on the package.</p></abstract>

In the present study we have determined some characteristics (aspect, odor, solubility, emulsion type, water and volatile substances content, total fatty matter, saponification index, ester index) for three pharmaceutical ointments belonging to the group of non-steroidal anti-inflammatory: Diclac, Ketonal, Indometacin and one antibiotic ointment for ophthalmic use: Ophtagram. In order to achieve stability study of studied ointments, the pH, the acidity index, the peroxide index and the iodine index were determined over a year every three months. After 9 months from the opening of the tubes, analytical determinations have shown that pH values, acidity, peroxide and iodine indexes no longer fit to the values recommended for medical use, which confirms the directions available on the package.

Characterization and stability study of some pharmaceutical ointments

Department of Chemistry and Chemical Engineering, Ovidius University, 124 Mamaia, Constanta 900527, Romania

Ovidius University Annals of Chemistry

{"article-title":"Characterization and stability study of some pharmaceutical ointments"}

In the present study we have determined some characteristics (aspect, odor, solubility, emulsion type, water and volatile substances content, total fatty...

Characterization and stability study of some pharmaceutical ointments

Published Online: Mar 22, 2013

Page range: 87 - 91

DOI: https://doi.org/10.2478/v10310-012-0014-5

Keywords
ointments, characteristics, stability study

This content is open access.

Characterization and stability study of some pharmaceutical ointments

Published Online: Mar 22, 2013

Page range: 87 - 91

DOI: https://doi.org/10.2478/v10310-012-0014-5

Keywordsointments, characteristics, stability study

This content is open access.

Keywords
ointments, characteristics, stability study