<abstract xmlns="http://www.w3.org/1999/xhtml"><p> The aim of this study was to present the cases with family history of type 1 diabetes in a group of pediatric patients from the Clinic of Pediatrics, Constanta County Hospital, and to analyze the risk for relatives conferred by presence of particular DR genotypes. 8 out of 60 index cases had relatives affected with type 1 diabetes (13.33%). Of these, four had firstdegree relatives affected (6.67%) and were presented here. Although high-risk genotypes were more frequent in the group of familial cases, no association was found between DR genotype and family history of type 1 diabetes when statistical significance was tested (p value 0.119).</p></abstract>

The aim of this study was to present the cases with family history of type 1 diabetes in a group of pediatric patients from the Clinic of Pediatrics, Constanta County Hospital, and to analyze the risk for relatives conferred by presence of particular DR genotypes. 8 out of 60 index cases had relatives affected with type 1 diabetes (13.33%). Of these, four had firstdegree relatives affected (6.67%) and were presented here. Although high-risk genotypes were more frequent in the group of familial cases, no association was found between DR genotype and family history of type 1 diabetes when statistical significance was tested (p value 0.119).

Analysis Of Family Cases With Type I Diabetes Mellitus In A Group Of Pediatric Patients From Constanţa County

ARS Medica Tomitana

This work is licensed under the Creative Commons Attribution-NonCommercial-NoDerivatives 3.0 License.

The aim of this study was to present the cases with family history of type 1 diabetes in a group of pediatric patients from the Clinic of Pediatrics, Constanta...

Analysis Of Family Cases With Type I Diabetes Mellitus In A Group Of Pediatric Patients From Constanţa County

Published Online: Feb 16, 2013

Page range: 13 - 18

DOI: https://doi.org/10.2478/v10307-012-0002-1

Keywords
type 1 diabetes, DR genotype, family history, genetic risk

© 2013

This work is licensed under the Creative Commons Attribution-NonCommercial-NoDerivatives 3.0 License.

Analysis Of Family Cases With Type I Diabetes Mellitus In A Group Of Pediatric Patients From Constanţa County

Published Online: Feb 16, 2013

Page range: 13 - 18

DOI: https://doi.org/10.2478/v10307-012-0002-1

Keywordstype 1 diabetes, DR genotype, family history, genetic risk

© 2013

This work is licensed under the Creative Commons Attribution-NonCommercial-NoDerivatives 3.0 License.

Keywords
type 1 diabetes, DR genotype, family history, genetic risk