<abstract xmlns="http://www.w3.org/1999/xhtml"><p> Infantile hemangiomas are the most common, benign vascular tumors of infancy. Their main feature is spontaneous involution over months to years after an initial phase of rapid proliferation. Small, superficial lesions usually resolve without sequel, but scarring and disfigurement are still possible, while the cosmetic outcome is unpredictable. Thus, inflantile hemangiomas benefit from non-aggressive topical treatment, because it is safe and with an overall outcome comparable to spontaneous involution. The available topical agents reported in the literature to satisfy these requirements are topical beta-blockers, imiquimod and topical corticosteroids. However, none of these have been assessed in randomized controlled trials, and standardized treatment recommendations about precise dosing and patient selection are not available yet.</p></abstract>

Infantile hemangiomas are the most common, benign vascular tumors of infancy. Their main feature is spontaneous involution over months to years after an initial phase of rapid proliferation. Small, superficial lesions usually resolve without sequel, but scarring and disfigurement are still possible, while the cosmetic outcome is unpredictable. Thus, inflantile hemangiomas benefit from non-aggressive topical treatment, because it is safe and with an overall outcome comparable to spontaneous involution. The available topical agents reported in the literature to satisfy these requirements are topical beta-blockers, imiquimod and topical corticosteroids. However, none of these have been assessed in randomized controlled trials, and standardized treatment recommendations about precise dosing and patient selection are not available yet.

Topical Treatment of Infantile Hemangiomas – Where Are We Now? / Topikalni tretman infantilnih hemangioma – gde smo danas?

Department of Dermatology and Venereology, Medical University – Sofia, Bulgaria

Serbian Journal of Dermatology and Venereology

Infantile hemangiomas are the most common, benign vascular tumors of infancy. Their main feature is spontaneous involution over months to years after an...

Topical Treatment of Infantile Hemangiomas – Where Are We Now? / Topikalni tretman infantilnih hemangioma – gde smo danas?

Published Online: Feb 12, 2013

Page range: 145 - 152

DOI: https://doi.org/10.2478/v10249-011-0046-4

Keywords
Hemangioma, diagnosis, therapy, Skin Neoplasms, Administration, Topical, Aminoquinolines, Neoplasm Regression, Spontaneous, Treatment Outcome

This content is open access.

Topical Treatment of Infantile Hemangiomas – Where Are We Now? / Topikalni tretman infantilnih hemangioma – gde smo danas?

Published Online: Feb 12, 2013

Page range: 145 - 152

DOI: https://doi.org/10.2478/v10249-011-0046-4

KeywordsHemangioma, diagnosis, therapy, Skin Neoplasms, Administration, Topical, Aminoquinolines, Neoplasm Regression, Spontaneous, Treatment Outcome

This content is open access.

Keywords
Hemangioma, diagnosis, therapy, Skin Neoplasms, Administration, Topical, Aminoquinolines, Neoplasm Regression, Spontaneous, Treatment Outcome