<abstract xmlns="http://www.w3.org/1999/xhtml">

<p> The aim of this study was the morphological characterisation of glioblastoma multiforme tumour grown <italic>in ovo</italic>. Tumour cells (U-87 MG) were implanted on the chorioallantoic membrane of chicken egg. The structural features of cultured tumours resembled the spontaneous glioblastoma multiforme; however, the differences were also indicated. Our results confirm applicability of <italic>in ovo </italic>culture in tumour genesis studies. The described novel model may be profoundly helpful for the future research on molecular mechanisms of tumour growth inhibition.</p>
</abstract>

The aim of this study was the morphological characterisation of glioblastoma multiforme tumour grown in ovo. Tumour cells (U-87 MG) were implanted on the chorioallantoic membrane of chicken egg. The structural features of cultured tumours resembled the spontaneous glioblastoma multiforme; however, the differences were also indicated. Our results confirm applicability of in ovo culture in tumour genesis studies. The described novel model may be profoundly helpful for the future research on molecular mechanisms of tumour growth inhibition.

Morphology of Human Glioblastoma Model Cultured in Ovo

Department of Morphological Science, Faculty of Veterinary Medicine

Department of Animal Nutrition and Feed, Faculty of Animal Science

Journal of Veterinary Research

{"article-title":"Morphology of Human Glioblastoma Model Cultured in Ovo"}

The aim of this study was the morphological characterisation of glioblastoma multiforme tumour grown in ovo. Tumour cells (U-87 MG) were implanted on the...

Morphology of Human Glioblastoma Model Cultured in Ovo

Published Online: Jan 17, 2013

Page range: 261 - 266

DOI: https://doi.org/10.2478/v10213-012-0046-9

This content is open access.