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Fibrosarcoma is a malignant spindle cell tumor of the soft tissues uniformly composed of collagen-producing cells capable of exhibiting varying degrees of fibroblastic differenciation. This diagnosis was more liberally applied to many types of spindle and pleomorphic cell sarcomas that exhibited fibrosarcoma-like patterns, e.g., malignant schwannoma, synovial sarcoma, malignant fibrous histiocytoma, and some benign fibroproliferative lesions, particularly fibromatosis and reactive tumor-like lesions.

The major challenge in the diagnosis lies in over and under diagnose of fibrosarcoma and underdiagnosis of reactive fibrosis. But this histologic differenciation is necessary owing to different treatment strategies.

ISSN:
1335-8421
Language:
English
Publication timeframe:
3 times per year
Journal Subjects:
Medicine, Clinical Medicine, Internal Medicine, Cardiology