<abstract xml:lang="en" xmlns="http://www.w3.org/1999/xhtml"><p>The objective of this study was to investigate the efficacy of <italic>Nelumbo nucifera</italic> and <italic>Aegle marmelos</italic> on common carp exposed to sub-lethal concentrations of combined heavy metals (5 ppm) under laboratory conditions. The fish were treated with <italic>Nelumbo nucifera</italic> (500 mg/kg bwt) and <italic>Aegle marmelos</italic> (500 mg/kgbwt) for 30 days as a dietary supplement. The blood biochemical parameters of the fish were evaluated by analyzing the level of red blood cells (RBC), packed cell volume (PCV), hemoglobin concentration, glucose, cholesterol, iron and copper. The findings of the present investigation showed significant increase in hemoglobin (<italic>p</italic>&lt;0.001), RBC (<italic>p</italic>&lt;0.01) and PCV (<italic>p</italic>&lt;0.01) of herbal drug-treated groups compared with metal-exposed fish. Conversely, glucose and cholesterol level in blood of common carp showed significant reduction compared with heavy-metal-exposed groups. All the values measured in <italic>Nelumbo nucifera</italic> and <italic>Aegle marmelos</italic> treated fish were restored comparably to control fish. Our results confirmed that <italic>Nelumbo nucifera</italic> and <italic>Aegle marmelos</italic> provide a detoxification mechanism for heavy metals in common carp.</p></abstract>

The objective of this study was to investigate the efficacy of Nelumbo nucifera and Aegle marmelos on common carp exposed to sub-lethal concentrations of combined heavy metals (5 ppm) under laboratory conditions. The fish were treated with Nelumbo nucifera (500 mg/kg bwt) and Aegle marmelos (500 mg/kgbwt) for 30 days as a dietary supplement. The blood biochemical parameters of the fish were evaluated by analyzing the level of red blood cells (RBC), packed cell volume (PCV), hemoglobin concentration, glucose, cholesterol, iron and copper. The findings of the present investigation showed significant increase in hemoglobin (p<0.001), RBC (p<0.01) and PCV (p<0.01) of herbal drug-treated groups compared with metal-exposed fish. Conversely, glucose and cholesterol level in blood of common carp showed significant reduction compared with heavy-metal-exposed groups. All the values measured in Nelumbo nucifera and Aegle marmelos treated fish were restored comparably to control fish. Our results confirmed that Nelumbo nucifera and Aegle marmelos provide a detoxification mechanism for heavy metals in common carp.

Detoxifying effect of <italic>Nelumbo nucifera</italic> and <italic>Aegle marmelos</italic> on hematological parameters of Common Carp (<italic>Cyprinus carpio</italic> L.)

Department of Advanced Zoology and Biotechnology, St. Xavier's College (Autonomous), Aquatic Biodiversity Research Center, Palayamkottai, Tamilnadu, India

Interdisciplinary Toxicology

Detoxifying effect of  and  on hematological parameters of Common Carp ( L.)

The objective of this study was to investigate the efficacy of Nelumbo nucifera and Aegle marmelos on common carp exposed to sub-lethal concentrations of...

Detoxifying effect of Nelumbo nucifera and Aegle marmelos on hematological parameters of Common Carp (Cyprinus carpio L.)

Published Online: Jan 28, 2011

Page range: 127 - 131

DOI: https://doi.org/10.2478/v10102-010-0052-9

Keywords
water quality, hemoglobin, glucose, common carp

This content is open access.