<abstract xml:lang="en" xmlns="http://www.w3.org/1999/xhtml">In this research, we report on the synthesis of warfarin acetals by using Preyssler's anion, [NaP5W30O110]-14 and heteropolyacids (HPAs) catalysts. This reaction was performed using methanol and ethanol at reflux temperature conditions. Under these conditions we have excellent yields and high selectivity. Preyssler heteropolyacid catalyst were easily recycled recovery and reused without the loss of its catalytic activities. The synthesis of warfarin acetals has been achieved using the catalytic amounts of green, inexpensive and eco-friendly Keggin types heteropolyacids. The products were obtained in high yields.</abstract>

In this research, we report on the synthesis of warfarin acetals by using Preyssler's anion, [NaP5W30O110]-14 and heteropolyacids (HPAs) catalysts. This reaction was performed using methanol and ethanol at reflux temperature conditions. Under these conditions we have excellent yields and high selectivity. Preyssler heteropolyacid catalyst were easily recycled recovery and reused without the loss of its catalytic activities. The synthesis of warfarin acetals has been achieved using the catalytic amounts of green, inexpensive and eco-friendly Keggin types heteropolyacids. The products were obtained in high yields.

Catalytic synthesis of warfarin acetals by using different heteropolyacid catalysts

Department of Chemistry, Islamic Azad University, Mashhad, IRAN

Agricultural Researches and Services Center, Mashhad, IRAN

Cluster for Molecular Chemistry, Department of Organic Chemistry, Radboud University Nijmegen, The Netherlands

Polish Journal of Chemical Technology

In this research, we report on the synthesis of warfarin acetals by using Preyssler's anion, [NaP5W30O110]-14 and heteropolyacids (HPAs) catalysts. This...

Catalytic synthesis of warfarin acetals by using different heteropolyacid catalysts

Published Online: Oct 05, 2011

Page range: 5 - 11

DOI: https://doi.org/10.2478/v10026-011-0029-2

Keywords
Heteropolyacid, Preyssler, Catalyst, Warfarin, Cyclic acetals

This content is open access.

Catalytic synthesis of warfarin acetals by using different heteropolyacid catalysts

Published Online: Oct 05, 2011

Page range: 5 - 11

DOI: https://doi.org/10.2478/v10026-011-0029-2

KeywordsHeteropolyacid, Preyssler, Catalyst, Warfarin, Cyclic acetals

This content is open access.

Keywords
Heteropolyacid, Preyssler, Catalyst, Warfarin, Cyclic acetals