Cite

Silverberg E, Lubera JA. Cancer statistics. CA Cancer J Clin 1988; 38: 5-22.Search in Google Scholar

Evans WK. Rationale for the treatment of nonsmall cell lung cancer. Lung Cancer 1993; 9(Suppl 2): S5-14.10.1016/0169-5002(93)90165-TSearch in Google Scholar

Travis WD, Lubin J, Ries L, Devesa S. United States lung carcinoma incidence trends: declining for the most histologic types among males, increasing among females. Cancer 1996; 77: 2464-70.10.1002/(SICI)1097-0142(19960615)77:12<2464::AID-CNCR8>3.0.CO;2-MSearch in Google Scholar

Potti A, Willardson J, Forseen C, Ganti AK, Koch M, Hebert B, et al. Predictive role of HER-2/neu overexpression and clinical features an initial presentation in patients with extensive stage small cell lung carcinoma. Lung Cancer 2002; 36: 257-61.10.1016/S0169-5002(01)00488-3Search in Google Scholar

Klijanienko J, Couturier J, Galut M, El-Naggar A, Maciorowski Z, Padoy E, et al. Detection and quantitation by fluorescence in situ hybridization (FISH) and image analysis of Her-2/neu gene amplification in breast cancer fine-needle samples. Cancer 1999; 87: 312-8.10.1002/(SICI)1097-0142(19991025)87:5<312::AID-CNCR12>3.0.CO;2-5Search in Google Scholar

Carraway KL 3rd, Cantley LC. A neu acquaintance for ErbB3 and ErbB4: a role for receptor heterodimerization in growth signaling. Cell 1944; 78: 5-8.Search in Google Scholar

Fernandes A, Hamburger AW, Gerwin BI. ErbB-2 kinase is required for constitutive STAT 3 activation in malignant human lung epithelial cells. Int J Cancer 1999; 83: 564-70.10.1002/(SICI)1097-0215(19991112)83:4<564::AID-IJC20>3.0.CO;2-QSearch in Google Scholar

Shi D, He G, Cao S, Pan W, Zhang HZ, Yu D, et al. Overexpression of the c-erbB-2/neu-encoded p185 protein in primary lung cancer. Mol Carcinog 1992; 5: 213-8.10.1002/mc.2940050308Search in Google Scholar

Akiyama T, Sudo C, Ogawara H, Toyoshima K, Yamamoto T. The product of human c-erbB-2 gene: A 185-kilodalton glycoprotein with tyrosine kinase activity. Science 1986; 42: 1644-6.10.1126/science.3012781Search in Google Scholar

Meert AP, Martin B, Paesmans M, Berghmans T, Mascaux C, Verdebout J-M, et al. The role of HER-2/neu expression on the survival of patients with lung cancer: a systematic review of the literature. Br J Cancer 2003; 89: 959-65.10.1038/sj.bjc.6601252Search in Google Scholar

Hung MC, Lau YK. Basic science of HER-2/neu: a review. Semin Oncol 1999; 26(Suppl 12): 51-9.Search in Google Scholar

Brodowicz T, Wiltschke C, Budinsky AC, Krainer M, Steger GG, Zielinski CC. Soluble HER-2/neu neutralizes biologic effects of anti-HER/2neu antibody on breast cancer cells in vitro. Int J Cancer 1997; 73: 875-9.10.1002/(SICI)1097-0215(19971210)73:6<875::AID-IJC19>3.0.CO;2-3Search in Google Scholar

Wright C, Angus B, Nisholson S, Sainsbury JR, Cairns JC, Gullick WJ, et al. Expression of the c-erbB-2 oncoprotein: a prognostic indicator in human breast cancer. Cancer Res 1989; 49: 2087-90.Search in Google Scholar

Jing X, Kakudo K, Murakami M, Nakamura Y, Nakamura M, Yokoi T, et al. Intraductal spread of invasive breast carcinoma has a positive correlation with c-erb B-2 overexpression and vascular invasion. Cancer 1999; 86: 439-48.10.1002/(SICI)1097-0142(19990801)86:3<439::AID-CNCR12>3.0.CO;2-USearch in Google Scholar

Agus DB, Bunn PA Jr, Franklin W, Garcia M, Ozols RF. HER-2/neu as a therapeutic target in non-small cell lung cancer, prostate cancer, and ovarian cancer. Semin Oncol 2000; 27: 92-100.Search in Google Scholar

Selvaggi G, Scagliotti GV, Torri V, Novello S, Leonardo E, Cappia S, et al. HER-2/neu overexpression in patients with radically resected nonsmall-cell lung carcinoma. Impact on long-term survival. Cancer 2002; 94: 2669-74.10.1002/cncr.10531Search in Google Scholar

Harpole DH, Marks JR, Richards WG, Herndon JE, Sugarbaker DJ. Localized adenocarcinoma of the lung: oncogene expression of erbB-2 and p53 in 150 patients. Clin Cancer Res 1995; 1: 659-64.Search in Google Scholar

Han H, Landeneau RJ, Santucci TS, Tung MY, Macherey RS, Shackney SE, et al. Prognostic value of immunohistochemical expression of p53, HER-2/neu, and bcl-2 in stage I non-small-cell lung cancer. Hum Pathol 2002; 33: 105-10.10.1053/hupa.2002.30183Search in Google Scholar

WHO. Histological typing of lung tumors. Am J Clin Pathol 1982; 77: 123-36.10.1093/ajcp/77.2.123Search in Google Scholar

Mountain CF. Revision in the international system for staging lung cancer. Chest 1997; 111: 1710-7.10.1378/chest.111.6.1710Search in Google Scholar

Slamon DJ, Clark GM, Wong SG, Levin WJ, Ullrich A, McGuire WL. Human breast cancer: correlation of relapse and survival with amplification of the erbB-2/neu oncogene. Science 1987; 235: 177-82.10.1126/science.3798106Search in Google Scholar

Tateishi M, Ishida T, Mitsudomi T, Kaneko S, Sugimachi K. Prognostic value of c-erbB-2 protein expression in human lung adenocarcinoma and squamous cell carcinoma. Eur J Cancer 1991; 27: 1372-5.10.1016/0277-5379(91)90012-3Search in Google Scholar

Kern JA, Schwartz DA, Nordberg JE, Weiner DB, Greene IM, Torney L, et al. p185 neu expression in human lung adenocarcinomas predicts shortened survival. Cancer Res 1990; 50: 5184-91.Search in Google Scholar

Shi D, He G, Cao S, Pan W, Zhang HZ, Yu D, et al. Overexpression of the c-erbB-2/neu-encoded p185 protein in primary lung cancer. Mol Carcinog 1992; 5: 213-8.10.1002/mc.2940050308Search in Google Scholar

Micke P, Hengstler JG, Ros R, Bittinger F, Metz T, Gebhard S, et al. C-ERB-2 expression in small-cell lumg cancer is associated with poor prognosis. Int J Cancer 2001; 92: 474-9.10.1002/ijc.1229Search in Google Scholar

Potti A, Ganti AK, Tuchman SA, Sholes K, Lagness E, Koka V, et al. Effect of pesticide exposure on HER-2/neu overexpression seen in patients with extensive stage small cell lung carcinoma. Clin Cancer Res 2003; 9: 4872-6.Search in Google Scholar

Pellegrini C, Falleni M, Marchetti A Cassani B, Miozzo M, Buttitta F, et al. HER-2/neu alterations in non-small cell lung cancer. Clin Cancer Res 2003; 9: 3645-52.Search in Google Scholar

Hsieh CC, Chow KC, Fahn HJ, Tsai CM, Li WY, Huang MH, et al. Prognostic significance of HER-2/neu overexpression in stage 1 adenocarcinoma of lung. Ann Thorac Surg 1998; 66: 1159-64.10.1016/S0003-4975(98)00792-9Search in Google Scholar

Ossaki T, Mitsudomi T, Oyama T, Nakanishi R, Yasumoto K. Serum level and tissue expression of c-erB-2 protein in lung adenocarcinoma. Chest 1995; 108: 157-62.10.1378/chest.108.1.1577606952Search in Google Scholar

Kim YC, Park KO, Kern JA, Park CS, Lim SC, Jang AS, et al. The interactive effect of Ras, HER2, P53 and Bcl-2 expression in predicting the survival of non-small cell lung cancer patients. Lung Cancer 1998; 22: 181-90.10.1016/S0169-5002(98)00086-5Search in Google Scholar

Pfeiffer P, Clausen PP, Andersen K. Lack of prognostic significance of epidermal growth factor receptor and oncoprotein p185 HER-2/neu in patients with systemically untreated non-small cell lung cancer: an immunohistochemical study on cryosections. Br J Cancer 1996; 74: 86-91.10.1038/bjc.1996.32020746108679464Search in Google Scholar

Pelosi G, Del Curto B, Dell'Orto P, Pasini F, Veronesi G, Spaggiari L, et al. Lack of prognostic implications of HER-2/neu abnormalities in 345stage I non small cell carcinomas and 207 stage I-III neuroendocrine tumours of the lung. Int J Cancer 2004; 113: 101-8.10.1002/ijc.2054215386424Search in Google Scholar

Pastorino U, Andreola S, Tagliabue E, Pezzela F, Incarbone M, Sozzi G, et al. Immunocytochemical markers in stage I lung cancer: relevance to prognosis. J Clin Oncol 1997; 15: 2858-65.10.1200/JCO.1997.15.8.28589256129Search in Google Scholar

Slamon DJ, Godolphin W, Jones LA. Studies of HER-2/neu proto-oncogene in human breast and ovarian cancer. Science 1989; 244: 707-12.10.1126/science.24701522470152Search in Google Scholar

Tsai CM, Chang KT, Wu LH, Chen JY, Gazdar AF, Mitsudomi T, et al. Correlation between intrinsic chemoresistance and HER-2/neu gene expression, p53gene mutations, and cell proliferation characteristics in non-small cell lung cancer cell lines. Cancer Res 1996; 56: 206-9.Search in Google Scholar

eISSN:
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Medicine, Clinical Medicine, Radiology, Internal Medicine, Haematology, Oncology