Design and evaluation of moxifloxacin hydrochloride ocular inserts

E. Barbu, I. Sarvaiya, K. L. Green, T. G. Nevell and J. Tsibouklis, Vinylpyrrolidone-co-(meth) acrylic acid inserts for ocular drug delivery: synthesis and evaluation, J. Biomed. Mater. Res. 74 (2005) 598-606; DOI: 10.1002/jbm.a.30329.10.1002/jbm.a.30329Search in Google Scholar

N. Gangopadhyay, M. Daniell, L. Weih and H. Taylor, Fluoroquinolone and fortified antibiotics for treating bacterial corneal ulcers, Br. J. Ophthalmol. 84 (2000) 378-384; DOI: 10.1136/bjo.84.4.378.10.1136/bjo.84.4.378Search in Google Scholar

A. P. Smith, M. Pennefather, S. B. Kaye and C. A. Hart, Fluoroquinolones: place in ocular therapy, Drugs 61 (2001) 747-761.Search in Google Scholar

P. E. Cutarelli, J. H. Lass, H. M. Lazarus, S. C. Putman and M. R. Jacobs, Topical fluoroquinolones: antimicrobial activity and in vitro corneal epithelial toxicity, Curr. Eye Res. 10 (1991) 557-563; DOI: 10.3109/02713689109001764.10.3109/02713689109001764Search in Google Scholar

P. L. Mallari, D. J. McCarty, M. Daniell and H. Taylor, Increased incidence of corneal perforation after topical fluoroquinolone treatment for microbial keratitis, Am. J. Ophthalmol. 131 (2001) 131-133; DOI: 10.1016/S0002-9394(00)00642-5.10.1016/S0002-9394(00)00642-5Search in Google Scholar

S. Barath and S. R. Hiremath, Ocular delivery system of perfloxacin mesylate, Pharmazie 54 (1999) 55-58.Search in Google Scholar

A. S. Mundada and B. K. Srikhande, Formulation and evaluation of ciprofloxacin hydrochloride soluble ocular drug insert, Curr. Eye Res. 33 (2008) 469-475; DOI: 10.1080/02713680802023104.10.1080/02713680802023104Search in Google Scholar

G. Di Colo, S. Burgalassi, P. Chetoni, M. P. Fiaschi, Y. Zambito and M. F. Saettone, Gel-forming erodible inserts for ocular controlled delivery of ofloxacin, Int. J. Pharm. 14 (2001) 101-111; DOI: 10.1016/S0378-5173(02)00421-0.10.1016/S0378-5173(02)00421-0Search in Google Scholar

J. M. Woodcock, J. M. Andrews, F. J. Boswell, N. P. Brenwald and R. Wise, In vitro activity of BAY 12-8039, a new fluoroquinolone, Antimicrob. Agents Chemother. 41 (1997) 101-106.10.1128/AAC.41.1.1011636688980763Search in Google Scholar

E. Pestova, J. J. Millichap, G. A. Noskin and L. R. Peterson, Intracellular targets of moxacifloxacin: a comparison with other fluoroquinolones, J. Antimicrob. Chemother. 45 (2000) 583-590; DOI: 10.1093/jac/45.5.583.10.1093/jac/45.5.58310797078Search in Google Scholar

P. K. Pawar and D. K. Majumdar, Effect of formulation factors on in vitro permeation of moxifloxacin from aqueous drops through excised goat, sheep and buffalo corneas, AAPS PharmSci Tech. 7 (2006) E13.10.1208/pt07011328290028Search in Google Scholar

P. K. Pawar and D. K. Majumdar, In vitro permeation characteristics of moxifloxacin from oil drops through excised goat, sheep, buffalo and rabbit corneas, Pharmazie 62 (2007) 853-857; DOI: 10.1691/PH.2007.11.7055.Search in Google Scholar

M. Malhotra and D. K. Majumdar, In vitro transcorneal permeation of ketorolac tromethamine from buffered and unbuffered aqueous ocular drops, Indian J. Exp. Biol. 35 (1997) 941-947.Search in Google Scholar

L. Perioli, V. Ambrogi, S. Giovagnoli, M. Ricci, P. Blasi and C. Rossi, Mucoadhesive bilayered tablets for buccal sustained release of flurbiprofen, AAPS PharmSciTech. 8 (2007) E54; DOI: 10.1208/pt0803054.10.1208/pt0803054275037317915804Search in Google Scholar

P. Costa and L. J. Manuel Sousa, Modeling and comparison of dissolution profiles, Eur. J. Pharm. Sci. 13 (2001) 123-133; DOI: 10.1016/S0928-0987(01)00095-1.10.1016/S0928-0987(01)00095-1Search in Google Scholar

V. Shankar, A. K. Chandrasekaran, S. Durga, G. Geetha and V. A. Ravichandran, Design and evaluation of diclofenac sodium ophthalmic inserts, Acta Pharm. Sci. 48 (2006) 5-10.Search in Google Scholar

International Conference on Harmonization, Q1A (R2): Stability Testing of New Drug Substances and Products, ICH, Geneva 2003.Search in Google Scholar