Open Access

Synthesis of coumarin heterocyclic derivatives with antioxidant activity and in vitro cytotoxic activity against tumour cells


Cite

C. A. Kontogiorgis and D. J. Hadjipavlou-Litina, Synthesis and biological evaluation of novel coumarin derivatives with a 7-azomethine linkage, Bioorg. Med. Chem. Lett. 14 (2004) 611--614.Search in Google Scholar

M. Ghate, D. Manohar, V. Kulkarni, R. Shobha and S. Y. Kattimani, Synthesis of vanillin ethers from 4-(bromomethyl) coumarins as anti-inflammatory agents, Eur. J. Med. Chem. 38 (2003) 297--302; DOI: 10.1016/S0223-5234(03)00016-3.10.1016/S0223-5234(03)00016-3Search in Google Scholar

D. N. Nicolaides, K. C. Fylaktakidou, K. E. Litinas and D. Hadjipavlou-Litina, Synthesis and biological evaluation of several coumarin-4-carboxamidoxime and 3-(coumarin-4-yl)-1,2,4-oxadiazole derivatives, Eur. J. Med. Chem. 33 (1998) 715--724.Search in Google Scholar

T. S. Jeong, K. S. Kim, J. R. Kim, K. H. Cho, S. Lee and W. S. Lee, Novel 3,5-diaryl pyrazolines and pyrazole as low-density lipoprotein (LDL) oxidation inhibitors, Bioorg. Med. Chem. Lett. 14 (2004) 2719--2723; DOI: 10.1016/j.bmcl.2004.03.072.10.1016/j.bmcl.2004.03.072Search in Google Scholar

T. Saibara, K. Toda, A. Wakatsuki, Y. Ogawa, M. Ono and S. Onishi, Protective effect of 3-methyl-1-phenyl-2-pyrazolin-5-one, a free radical scavenger, on acute toxicity of paraquat in mice, Toxicol. Lett. 143 (2003) 51--54; DOI: 10.1016/S0378-4274(03)00113-9.10.1016/S0378-4274(03)00113-9Search in Google Scholar

M. H. Shih and F. Y. Ke, Synthesis and evaluation of antioxidant activity of sydnonyl substituted thiazolidinone and thiazoline derivatives, Bioorg. Med. Chem. 12 (2004) 4633--4643; DOI: 10.1016/j.bmc.2004.06.033.10.1016/j.bmc.2004.06.03315358290Search in Google Scholar

R. Lin, G. Chiu, Y. Yu, P. J. Connolly, S. Li, Y. Lu, M. Adams, A. R. Fuentes-Pesquera, S. L. Emanuel and L. M. Greenberger, Design, synthesis, and evaluation of 3,4-disubstituted pyrazole analogues as anti-tumor CDK inhibitors, Bioorg. Med. Chem. Lett. 17 (2007) 4557--4561; DOI: 10.1016/j.bmcl.2007.05.092.10.1016/j.bmcl.2007.05.09217574416Search in Google Scholar

Y. Kakiuchi, N. Sasaki, M. Satoh-Masuoka, H. Murofushi and K. Murakami-Murofushi, A novel pyrazolone, 4,4-dichloro-1-(2,4-dichlorophenyl)-3-methyl-5-pyrazolone, as a potent catalytic inhibitor of human telomerase, Biochem. Biophys. Res. Commun. 320 (2004) 1351--1358; DOI: 10.1016/j.bbrc.2004.06.094.10.1016/j.bbrc.2004.06.09415303281Search in Google Scholar

V. P. M. Rahman, S. Mukhtar, W. H. Ansari and G. Lemiere, Synthesis, stereochemistry and biological activity of some novel long alkyl chain substituted thiazolidin-4-ones and thiazan-4-one from 10-undecenoic acid hydrazide, Eur. J. Med. Chem. 40 (2005) 173--184; DOI: 10.1016/j.ejmech.2004.10.003.10.1016/j.ejmech.2004.10.00315694652Search in Google Scholar

S. Rollas, N. Gulerman and H. Erdeniz, Synthesis and antimicrobial activity of some new hydrazones of 4-fluorobenzoic acid hydrazide and 3-acetyl-2,5-disubstituted-1,3,4-oxadiazolines, Farmaco 57 (2002) 171--174.Search in Google Scholar

M. S. Y. Khan and M. Akhtar, Synthesis of some new 2,5-disubstituted 1,3,4-oxadiazole derivatives and their biological activity, Indian J. Chem. 42B (2003) 900--904.10.1002/chin.200332096Search in Google Scholar

P. V. Ramana and L. K. Ravindranath, Synthesis of N'-(2-hydroxybenzoyl)-3-methyl-4-(substituted-phenylhydrazono)-2-pyrazolin-5-ones, J. Indian Chem. Soc. 76 (1999) 112--113.Search in Google Scholar

V. Dhingra, R. Bhatawdekar and L. Agarwal, Synthesis and biological activity of some 1-substituted anilinomalonyl-3, 5-disubstituted-4-substituted-phenylazopyrazoles, J. Indian Chem. Soc. 68 (1991) 672--673.Search in Google Scholar

U. Gupta, V. Sareen, V. Khatri and S. Chugh, Synthesis and antifungal activity of new fluorine containing 4-(substitutedphenyl) hydrazono-3-methyl-2-pyrazolin-5-ones and 2-isoxazolin-5-ones, Indian J. Heteroc. Chem. 13 (2004) 351--354.Search in Google Scholar

T. D. Babu, G. Kuttan and J. Padikkala, Cytotoxic and antitumour properties of certain taxa of Umbelliferae with special reference to Centella asiatica (L.) Urban, J. Ethnopharmacol. 48 (1995) 53--57.Search in Google Scholar

eISSN:
1846-9558
ISSN:
1330-0075
Language:
English
Publication timeframe:
4 times per year
Journal Subjects:
Pharmacy, other