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Use of chemometrics for development and validation of an RP-HPLC method for simultaneous determination of haloperidol and related compounds


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E. Mutschler, H. Derendorf, M. Schhäfer-Korting, K. Elord and K. S. Estes, in Drug Actions, Basic Principles and Therapeutic Aspects, Medpharm Scientific Publishers, Stuttgart 1995, pp. 116-125.Search in Google Scholar

T. Arinobu, H. Hattori, M. Iwai, A. Ishii, T. Kumazawa, O. Suzuki and H. Seno, Liquid chromatographic-mass spectrometric determination of haloperidol and its metabolites in human plasma and urine, J. Chromatogr.B 776 (2002) 107-113; DOI:10.1016/S1570-0232(02)00175-7.10.1016/S1570-0232(02)00175-7Search in Google Scholar

G. Theodoridis, M. A. Lontou, F. Michopoulos, M. Sucha and T. Gondova, Study of multiple solid-phase micro extraction combined off-line with high performance liquid chromatography. Application in the analysis of pharmaceuticals in urine, Anal. Chim. Acta 516 (2004) 197-204; DOI: 10.1016/j.aca.2004.04.012.10.1016/j.aca.2004.04.012Search in Google Scholar

S. Ouanes, M. Kallel, H. Trabels, F. Safta and K. Bouzouita, Zero-crossing derivative spectro-photometry for the determination of haloperidol in presence of parabens, J. Pharm. Biomed. Anal. 17 (1998) 361-364; DOI: 10.1016/S0731-7085(97)00174-X.10.1016/S0731-7085(97)00174-XSearch in Google Scholar

H. S. El-Desoky and M. M. Ghoneim, Assay of the anti-psychotic drug haloperidol in bulk form, pharmaceutical formulation and biological fluids using square-wave adsorptive stripping voltammetry at a mercury electrode, J. Pharm. Biomed. Anal. 38 (2005) 543-550; DOI: 10.1016/j.jpba.2005.01.017.10.1016/j.jpba.2005.01.017Search in Google Scholar

P. Cutroneo, M. Beljean, R. Phan Tan Luuc and A.-M. Siouffi, Optimization of the separation of some psychotropic drugs and their respective metabolites by liquid chromatography, J. Pharm. Biomed. Anal. 41 (2006) 333-340; DOI: 10.1016/j.jpba.2005.10.050.10.1016/j.jpba.2005.10.050Search in Google Scholar

R. Driouichl, H. Trabelsi and K. A. Bouzouita, Stability-indicating assay for haloperidol syrup by high-performance liquid chromatography, Chromatographia 53 (2001) 629-634; DOI: 10.1007/ BF02493010.10.1007/BF02493010Search in Google Scholar

H. Trabelsi, S. Bouabdallah, K. Bouzouita and F. Safta, Determination and degradation study of haloperidol by high performance liquid chromatography, J. Pharm. Biomed. Anal. 29 (2002) 649-657; DOI: 10.1016/S0731-7085(02)00104-8.10.1016/S0731-7085(02)00104-8Search in Google Scholar

International Conference on Harmonization (ICH): Q3A (R2), Impurities in New Drug Substances, EMEA, London 2006.Search in Google Scholar

M. Franck, Impurity Profiling with the Agilent 1200 Series LC System Part 3: Rapid Condition Scouting for Method Development, Agilent Application Note, Agilent Technologies Inc., Waldbronn, 2006; Publication Number 5989-5619EN.Search in Google Scholar

M. Joseph, High-throughput HPLC with Short Columns and New Sub Two-micron Particles, Agilent Application Note, Agilent Technologies Inc., New York, 2003; Publication Number 5988-9615EN.Search in Google Scholar

T. Lundsted, E. Seifert, L. Abramo, B. Thelin, A. Nystorm, J. Pettersen and R. Bergman, Experimental design and optimization, Chemom. Intell. Lab. Syst. 42 (1998) 3-40; DOI: 10.1016/S0169-7439(98)00065-3.10.1016/S0169-7439(98)00065-3Search in Google Scholar

P. W. Araujo and R. G. Brereton, Experimental design II. Optimization. Trends Anal. Chem. 15 (1996) 63-68; DOI: 10.1016/0165-9936(96)80762-X.10.1016/0165-9936(96)80762-XSearch in Google Scholar

S. N. Deming and S. L. Morgan, Experimental Design: A Chemometric Approach, Elsevier, Amsterdam, 1993.Search in Google Scholar

D. Bylund, A. Bergens and S. P. Jacobsson, Optimization of chromatographic separations by use of a chromatographic response function, empirical modeling and multivariate analysis, Chromatographia 44 (1997) 74-80; DOI: 10.1007/BF02466519.10.1007/BF02466519Search in Google Scholar

International Conference on Harmonization (ICH): Q2 (R1), Validation of Analytical Procedures: Text and Methodology, EMEA, London 2005.Search in Google Scholar

H. Fabre, Robustness testing in liquid chromatography and capillary electrophoresis, J. Pharm. Biomed. Anal. 14 (1996) 1125-1132; DOI: 10.1016/s0731-7085(96)01770-0.10.1016/S0731-7085(96)01770-0Search in Google Scholar

G. A. Lewis, D. Mathieu and R. Phan-Tan-Luu, Pharmaceutical Experimental Design, Marcel Decker, New York 199910.1201/9780203508688Search in Google Scholar

eISSN:
1846-9558
ISSN:
1330-0075
Language:
English
Publication timeframe:
4 times per year
Journal Subjects:
Pharmacy, other