Mannan-coated gelatin nanoparticles for sustained and targeted delivery of didanosine: In vitro and in vivo evaluation

M. S. Meltzer, D. R. Skillman, P. J. Gomatos, D. C. Kalter and H. C. Gendelman, Role of mononuclear phagocytosis in the pathogenesis of human immunodeficiency virus infection, Annu. Rev. Immunol.8 (1990)169-194; DOI: 10.1146/annurev.iy.08.040190.001125.10.1146/annurev.iy.08.040190.001125Search in Google Scholar

S. Aquaro, R. Calio, J. Balzarini, M. C. Bellocchi, E. Garaci and C. F. Perno, Macrophages and HIV infection: therapeutical approaches toward this strategic virus reservoir, Antiviral Res.55 (2002) 209-225; DOI: 10.1016/S0166-3542(02)00052-9.10.1016/S0166-3542(02)00052-9Search in Google Scholar

C. Oussoren, M. Magnani, A. Fraternale, A. Casabianca, L. Chiarantini, R. Ingebrigsten, W. J. M. Underberg and G. Strome, Liposomes as carrier of the antiretroviral agent dideoxycytidine-5'-triphosphate, Int. J. Pharm.180 (1999) 261-270; DOI: 10.1016/S0378-5173(99)00016-2.10.1016/S0378-5173(99)00016-2Search in Google Scholar

V. Schafer, H. V. Briesen, H. Rubsamen-Waigmann, A. M. Steffan, C. Royer and J. Kreuter, Phagocytosis and degradation of human serum albumin microspheres and nanoparticles in human macrophages, J. Microencaps.11 (1994) 261-269; DOI: 10.3109/02652049409040455.10.3109/02652049409040455Search in Google Scholar

Z. Cui, C. H. Hsu and R. J. Mumper, Physical characterization and macrophage cell uptake of mannan-coated nanoparticles, Drug Dev. Ind. Pharm.29 (2003) 689-700; DOI: 10.1081/DDC-120021318.10.1081/DDC-120021318Search in Google Scholar

F. Ahsan, I. P. Rivas, M. A. Khan and A. I. T. Suarez, Targeting of macrophage: role of physicochemical properties of particulate carriers-liposomes and microsphere on the phagocytosis by macrophages, J. Control. Rel.79 (2002) 29-40; DOI: 10.1016/S0168-3659(01)00549-1.10.1016/S0168-3659(01)00549-1Search in Google Scholar

J. Kreuter, Nanoparticulate system for brain delivery of drugs, Adv. Drug Deliv. Rev.47 (2001) 65-81; DOI: 10.1016/S0169-409X(00)00122-8.10.1016/S0169-409X(00)00122-8Search in Google Scholar

M. S. Wadhwa and K. G. Rice, Receptor mediated glycotargeting, J. Drug Target.11 (2003) 255-268; DOI: 10.1080/10611860310001636557.10.1080/10611860310001636557Search in Google Scholar

J. Shao and J. K. H. Ma, Characterization of mannosylphospholipid liposome system for drug targeting to alveolar macrophages, J. Drug Deliv. Target. Ther. Agents4 (1997) 43-48.Search in Google Scholar

Y. Gabr, N. Assem, A. Micheal and L. Fahmy, Evaluation studies on oxypolygelatin and degraded gelatin as plasma volume expanders, Arzneimittelforschung46 (1996) 763-766.Search in Google Scholar

R. Yarchoan, H. Mitsuya, R. V. Thomas, J. M. Pluda, N. R. Hartman and C. F. Perno, In vivo activity against HIV and favorable toxicity profile of 2'3'-dideoxyinosine, Science245 (1989) 412-417.10.1126/science.25028402502840Search in Google Scholar

T. P. Cooley, M. L. Kunches, C. A. Saunders, C. J. Perkins, S. L. Kelley, C. McLaren, R. P. McCaffrey and H. A Liebman, Treatment of AIDS and AIDS related complex with 2'3'-dideoxyinosine given once daily, Rev. Infect. Dis.12 (1990) S552-S560.10.1093/clinids/12.Supplement_5.S552Search in Google Scholar

C. J. Coester, K. Langer, H. Von Briesen and J. Kreuter, Gelatin nanoparticles by two step desolvation - A new preparation method, surface modification and cell uptake, J. Microencaps.17 (2000) 187-193; DOI: 10.1080/026520400288427.10.1080/026520400288427Search in Google Scholar

J. Vandervoort and A. Ludwig, Preparation and evaluation of drug-loaded gelatin nanoparticles for topical ophthalmic use, Eur. J. Pharm. Biopharm.57 (2004) 251-261; DOI: 10.1016/S0939-6411(03)00187-5.10.1016/S0939-6411(03)00187-5Search in Google Scholar

E. Rebasamen, W. Goldinger, W. Scheirer, O. W. Merten and G. E. Palfe, Development in Biological Standardization, in Advances in Animal Cell Technology and Cell Engineering: Evaluation and Exploitation (Eds. R. Spier and W. Hennessen), Vol. 66, ESACT, Basel 1987, pp. 557-583.Search in Google Scholar

V. F. Courtney, R. C. Brundage, R. P. Remmel, L. M. Page, D. Weller, N. R. Calles, C. Simon and M. W. Kline, Pharmacologic characteristic of indinavir, didanosine and stavudine in human immunodeficiency virus-infected children receiving combination therapy, Antimicrob. Agents Chemother.44 (2000) 1029-1034.10.1128/AAC.44.4.1029-1034.2000Search in Google Scholar

S. Jain, R. Sapre, A. K. Tiwary and N. K. Jain, Proultraflexible lipid vesicles for effective transdermal delivery of levonorgestrel: Development, characterization and performance evaluation, AAPS PharmSciTech.6 (2005) E513-E522; DOI: 10.1208/pt060364.10.1208/pt060364Search in Google Scholar

S. Kaul, W. C. Shyu, U. A. Shukla, K. A. Dandekar and R. H. Barbhaiya, Pharmacologic characteristic of indinavir, didanosine and stavudine in human immunodeficiency Virus-Infected children receiving combination therapy, Drug Metab. Dispos.21 (1993) 447-453.Search in Google Scholar

E. Mukherji, N. J. Millenbaugh and J. L. S. Au, Percutaneous absorption of 2',3'-dideoxyinosine in rats, Pharm. Res.11 (1994) 809-815.10.1023/A:1018965305234Search in Google Scholar

O. Bekers, J. H. Beijnen, M. J. T. Klein Tank, D. M. Burger, P. I. Meenhorst, A. J. P. F. Lombarts and W. J. M. Underberg, 2',3'-dideoxyinosine (ddI): Its chemical stability and cyclodextrin complexation in aqueous media, J. Pharm. Biomed. Anal.11 (1993) 489-493; DOI: 10.1016/0731-7085(93)80162-T.10.1016/0731-7085(93)80162-TSearch in Google Scholar

P. T. Tayade and R. D. Kale, Encapsulation of water-insoluble drug by a cross-linking technique: Effect of process and formulation variables on encapsulation efficiency, particle size, and in vitro dissolution rate, AAPS Pharm. Sci6 (2004); DOI: 10.1208/ps060112.10.1208/ps060112Search in Google Scholar

C. Sanchez-Lafuente, A. M. Rabasco, J. Alvarez-Fuentes and M. Fernandez-Arevalo, Eudragit® RS-PM and Ethocel® 100 premium: influence over the behavior of didanosine inert matrix system, Farmaco57 (2002) 649-656; DOI: 10.1016/S0014-827X(02)01240-5.10.1016/S0014-827X(02)01240-5Search in Google Scholar

V. Apostolopoulos and I. F. McKenzie, Role of the mannose receptor in the immune response, Curr. Mol. Med.1 (2001) 469-474; DOI:10.2174/1566524013363645.10.2174/1566524013363645Search in Google Scholar

C. A. Hoppe and Y. C. Lee, The binding and processing of mannose-bovine serum albumin derivatives by rabbit alveolar macrophages. Effect of the sugar density, J. Biol. Chem.258 (1983) 14193-14199.10.1016/S0021-9258(17)43844-0Search in Google Scholar

M. Velinova, N. Read, C. Kirby and G. Gregoriadis, Morphological observation on the fate of liposomes in the regional lymph nodes after footpad injection into rats, Biochim. Biophys. Acta1299 (1996) 207-215; DOI: 10.1016/0005-2760(95)00208-1.10.1016/0005-2760(95)00208-1Search in Google Scholar