<abstract xml:lang="en" xmlns="http://www.w3.org/1999/xhtml"><p>In addition to several well-known drug delivery strategies developed to facilitate effective chemotherapy with anticancer agents, some new approaches have been recently established, based on specific effects arising from the applications of ultrasound, magnetic and electric fields on drug delivery systems. This paper gives an overview of newly developed methods of drug delivery to tumors and of the related anticancer therapies based on the combined use of different physical methods and specific drug carriers. The conventional strategies and new approaches have been put into perspective to revisit the existing and to propose new directions to overcome the threatening problem of cancer diseases.</p></abstract>

In addition to several well-known drug delivery strategies developed to facilitate effective chemotherapy with anticancer agents, some new approaches have been recently established, based on specific effects arising from the applications of ultrasound, magnetic and electric fields on drug delivery systems. This paper gives an overview of newly developed methods of drug delivery to tumors and of the related anticancer therapies based on the combined use of different physical methods and specific drug carriers. The conventional strategies and new approaches have been put into perspective to revisit the existing and to propose new directions to overcome the threatening problem of cancer diseases.

Physical mechanisms and methods employed in drug delivery to tumors

Department of Biophysics, Faculty of Pharmacy and Biochemistry, University of Zagreb, 10002 Zagreb, Croatia

Acta Pharmaceutica

{"article-title":"Physical mechanisms and methods employed in drug delivery to tumors"}

In addition to several well-known drug delivery strategies developed to facilitate effective chemotherapy with anticancer agents, some new approaches have been...

Physical mechanisms and methods employed in drug delivery to tumors

Published Online: Sep 18, 2007

Page range: 249 - 268

DOI: https://doi.org/10.2478/v10007-007-0021-9

Keywords
prijenos lijekova, ultrazvuk, sonoporacija, EPR, magnetoliposomi, magnetska hipertermija, elektrokemoterapija, elektroporacija

This content is open access.

Physical mechanisms and methods employed in drug delivery to tumors

Published Online: Sep 18, 2007

Page range: 249 - 268

DOI: https://doi.org/10.2478/v10007-007-0021-9

Keywordsprijenos lijekova, ultrazvuk, sonoporacija, EPR, magnetoliposomi, magnetska hipertermija, elektrokemoterapija, elektroporacija

This content is open access.

Keywords
prijenos lijekova, ultrazvuk, sonoporacija, EPR, magnetoliposomi, magnetska hipertermija, elektrokemoterapija, elektroporacija