Open Access

Design and characterization of chitosan-containing mucoadhesive buccal patches of propranolol hydrochloride


Cite

A. J. Hoogstraate, J. C. Verhoef, B. Tuk, A. Pijpers, L. A. M. G. van Leengoed, J. H. M. Verheijden, H. E. Junginger and H. E. Bodde, In vitro buccal delivery of fluorescein isothiocyanate - dextran 4400 with glycodeoxycholate as an absorption enhancer in pigs, J. Pharm. Sci. 85 (1996) 457-460.10.1021/js950129kSearch in Google Scholar

J. Ali, R. K. Khar and A. Ahuja, Formulation and characterization of a buccoadhesive erodible tablet for the treatment of oral lesions, Pharmazie 53 (1998) 329-334.Search in Google Scholar

Y. Kohda, H. Kobayashi, Y. Baba, H. Yuasa, T. Ozeki, Y. Kanaya and E. Sagara, Controlled release of lidocaine hydrochloride from buccal mucosa-adhesive films with solid dispersion, Int. J. Pharm. 15 (1983) 147-155.Search in Google Scholar

M. M. Nair and Y. W. Chien, Development of anticandidal delivery systems. (II) Mucoadhesive devices for prolonged drug delivery in the oral cavity, Drug Dev. Ind. Pharm. 22 (1996) 243-253.10.3109/03639049609058568Search in Google Scholar

B. Parodi, E. Russo, G. Caviglioli, S. Cafaggi and G. Bignardi, Development and characterization of a buccoadhesive dosage form of oxycodone hydrochloride, Drug Dev. Ind. Pharm. 22 (1996) 445-450.10.3109/03639049609069353Search in Google Scholar

R. Hango, S. Kavimani, A. R. Mullaicharam and B. Jayakar, In vitro studies on buccal strips of glibenclamide using chitosan, Ind. J. Pharm. Sci. 59 (1997) 232-235.Search in Google Scholar

K. D. Bremecker, H. Strempel and G. Klein, Novel concept for a mucosal adhesive ointment, J. Pharm. Sci. 73 (1984) 548-552.10.1002/jps.2600730429Search in Google Scholar

S. C. Shin, J. P. Bum and J. S. Choi, Enhanced bioavailability by buccal administration of triamcinolone acetonide from the bioadhesive gels in rabbits, Int. J. Pharm. 209 (2000) 37-43.10.1016/S0378-5173(00)00542-1Search in Google Scholar

J. M. Gu, J. R. Robinson and S. H. S. Leung, Binding of acrylic polymers to mucin/epithelial surfaces: Structure-property relationships, CRC Crit. Rev. Ther. Drug Carrier Systems 21 (1988) 21-67.Search in Google Scholar

C. M. Lehr, J. A. Bouwstra, E. H. Schacht and H. E. Junginger, In vitro evaluation of mucoadhesive properties of chitosan and some other natural polymers, Int. J. Pharm. 78 (1992) 43-48.10.1016/0378-5173(92)90353-4Search in Google Scholar

R. A. A. Muzarelli, Chitin, Pergamon Press, Oxford 1977.Search in Google Scholar

S. Hirano, H. Seino, I. Akiyama and I. Nonaka, Chitosan a Biocompatible Material for Oral and Intravenous Administrations: Progress in Biomedical Polymers, Plenum Press, New York 1990, pp. 283-289.10.1007/978-1-4899-0768-4_28Search in Google Scholar

T. Nagai, Y. Sawayanagi and N. Nambu, Application of Chitin and Chitosan to Pharmaceutical Preparations: Chitin, Chitosan and Related Enzymes, Academic Press, Orlando 1984, pp. 21-39.10.1016/B978-0-12-780950-2.50008-3Search in Google Scholar

K. Y. Inouye, T. Machida, Sannan and T. Nagai, Buoyant sustained release tablets based on chitosan, Drug Des. Deliv. 2 (1988) 165-175.Search in Google Scholar

C. Ramunan-Lopez and R. Bodmeier, Mechanical and water vapor transmission properties of polysaccharide films, Drug Dev. Ind. Pharm. 22 (1996) 1201-1209.10.3109/03639049609063238Search in Google Scholar

B. B. Hoffman and R. J. Lefkowitz, Goodman and Gillman's: The Pharmacological Basis of Therapeutics, 9th ed., Mc Graw-Hill, New Delhi 1994, pp. 128-130.Search in Google Scholar

Y. Sawayanaga, N. Nambu and T. Nagai, Permeation of drugs through chitosan membranes, Chem. Pharm. Bull. 30 (1982) 3297-3301.10.1248/cpb.30.3297Search in Google Scholar

R. Khurana, A. Ahuja and R. K. Khar, Development and evaluation of mucoadhesive films of miconazole nitrate, Indian J. Pharm. Sci. 60 (2000) 449-453.Search in Google Scholar

J. Kemken, A. Ziegler and B. W. Muller, Pharmacodynamic effects of transdermal bupranolol and timolol in vivo: comparison of micro emulsions and matrix patches as vehicles, Math. Find. Exp. Clin. Pharmacol. 13 (1991) 361-365.Search in Google Scholar

Pharmacopoeia of India, 3rd ed., Controller of Publications, New Delhi 1996, p. 634.Search in Google Scholar

A. S. Gupta, Garg and R. K. Khar, Measurement of bioadhesive strength of muco-adhesive buccal tablets: design of an in vitro assembly, Indian Drugs 30 (1992) 152-155.Search in Google Scholar

R. Y. Han, J. Y. Fang, K. C. Sung and O. Y. P. Hu, Mucoadhesive buccal disks for novel nalbuphine prodrug controlled delivery: effect of formulation variables on drug release and mucoadhesive performance, Int. J. Pharm. 177 (1999) 201-209.Search in Google Scholar

P. Bottenberg, R. Cleymaet, C. D. Muynek, J. P. Remon, D. Coomans and D. Slop, Development and testing of bioadhesive, fluoride containing slow-release tablets for oral use, J. Pharm. Pharmacol. 43 (1991) 457-464.10.1111/j.2042-7158.1991.tb03514.xSearch in Google Scholar

USP, 23/NF 18, USP Convention, Rockville 1995, pp. 1792-1795.Search in Google Scholar

N. A. Peppas and P. A. Bury, Surface interfacial and molecular aspects of polymer bioadhesion on soft tissues, J. Control Rel. 2 (1985) 257-275.10.1016/0168-3659(85)90050-1Search in Google Scholar

H. Park and J. R. Robinson, Mechanisms of bioadhesion of poly(acrylic acid) hydrogels, Pharm. Res. 4 (1987) 457-464.10.1023/A:1016467219657Search in Google Scholar

R. W. Korsmeyer, R. Gurny, E. Doelker, P. Buri and N. A. Peppas, Mechanisms of solute release from porous hydrophilic polymers, Int. J. Pharm. 15 (1983) 25-35.10.1016/0378-5173(83)90064-9Search in Google Scholar

N. A. Peppas, Analysis of Fickian and non-Fickian drug release from polymers, Pharm. Acta Helv. 60 (1985) 110-111.Search in Google Scholar

eISSN:
1846-9558
ISSN:
1330-0075
Language:
English
Publication timeframe:
4 times per year
Journal Subjects:
Pharmacy, other