<abstract xmlns="http://www.w3.org/1999/xhtml"><sec><h3>Introduction</h3><p>Due to the availability of the EQ-5D-5L instrument official translation into Slovenian its use is widespread in Slovenia. However, the health profiles obtained in many studies cannot be ascribed their appropriate values as the EQ-5D-5L value set does not yet exist in Slovenia. Our aim was to estimate an interim EQ-5D-5L value set for Slovenia using the crosswalk methodology developed by the EuroQol Group on the basis of the EQ-5D-3L Slovenian TTO value set. Our secondary aim was to compare the interim values obtained with the EQ-5D-3L Slovenian values.</p></sec><sec><h3>Methods</h3><p>To obtain a Slovenian interim EQ-5D-5L value set, we applied the crosswalk methodology developed by the EuroQol Group to the Slovenian EQ-5D-3L TTO value set. We examined the differences between values by comparing the mean 3L and 5L value scores and the distribution of values across all respondents.</p></sec><sec><h3>Results</h3><p>By definition, 3-level and 5-level versions have the same range (from 1 to −0.495) and a health state coded 22222 in the 3-level version corresponds to 33333 in the 5-level version. While the addition of a “slight” severity level (22222) in the 5-level version has a low informational value, the addition of a “severe” health state (44444) covers larger range of the scale. The 5-level version results in fewer health states being valued below 0 and above 0.8.</p></sec><sec><h3>Conclusion</h3><p>The EQ-5D-5L value set, based on the crosswalk methodology, should be used until a value set for the EQ-5D-5L is derived from preferences elicited directly from a representative sample of the Slovenian general population.</p></sec></abstract>

IntroductionDue to the availability of the EQ-5D-5L instrument official translation into Slovenian its use is widespread in Slovenia. However, the health profiles obtained in many studies cannot be ascribed their appropriate values as the EQ-5D-5L value set does not yet exist in Slovenia. Our aim was to estimate an interim EQ-5D-5L value set for Slovenia using the crosswalk methodology developed by the EuroQol Group on the basis of the EQ-5D-3L Slovenian TTO value set. Our secondary aim was to compare the interim values obtained with the EQ-5D-3L Slovenian values.MethodsTo obtain a Slovenian interim EQ-5D-5L value set, we applied the crosswalk methodology developed by the EuroQol Group to the Slovenian EQ-5D-3L TTO value set. We examined the differences between values by comparing the mean 3L and 5L value scores and the distribution of values across all respondents.ResultsBy definition, 3-level and 5-level versions have the same range (from 1 to −0.495) and a health state coded 22222 in the 3-level version corresponds to 33333 in the 5-level version. While the addition of a “slight” severity level (22222) in the 5-level version has a low informational value, the addition of a “severe” health state (44444) covers larger range of the scale. The 5-level version results in fewer health states being valued below 0 and above 0.8.ConclusionThe EQ-5D-5L value set, based on the crosswalk methodology, should be used until a value set for the EQ-5D-5L is derived from preferences elicited directly from a representative sample of the Slovenian general population.

Crosswalk EQ-5D-5L Value Set for Slovenia

Slovenian Journal of Public Health

This work is licensed under the Creative Commons Attribution-NonCommercial-NoDerivatives 3.0 License.

PREHODNI EQ-5D-5L VREDNOSTNI SET ZA SLOVENIJO

IntroductionDue to the availability of the EQ-5D-5L instrument official translation into Slovenian its use is widespread in Slovenia. However, the health...

Parameter	Slovenian EQ-5D-3L Crosswalk value set	Slovenian EQ-5D-5L value set
Number of health states	243	3125
Range	−0.495 to 1	−0.495 to 1
Mean±SD	0.18±0.324	0.258±0.27
Median	0.190	0.304
Skewness	0.070	−0.419
Kurtosis	2.170	2.450
States worse than dead (index <0), n (%)	82 (33.745%)	653 (20.896%)
States with index >0.8, n (%)	4 (1.646%)	16 (0.512%)

EQ-5D-3L	EQ-D5-5L	Utility
11111	11111	1.000
.	11211	0.894
.	11112	0.885
.	12111	0.879
.	11121	0.836
.	21111	0.747
.	11222	0.741
.	12221	0.738
.	22211	0.666
.	22222	0.580
.	23332	0.555
.	22333	0.554
.	33322	0.543
22222	33333	0.524
.	44433	0.392
.	34443	0.315
.	33444	0.277
.	44444	0.208
.	44555	−0.075
.	45554	−0.102
.	55544	−0.351
33333	55555	−0.495

Crosswalk EQ-5D-5L Value Set for Slovenia

Article Category: Original scientific article

Published Online: Jun 25, 2020

Page range: 189 - 194

Received: Apr 04, 2020

Accepted: Jun 09, 2020

DOI: https://doi.org/10.2478/sjph-2020-0024

Keywords
EuroQol, EQ-5D-5L, interim value set, health-related quality of life, patient-reported outcomes

© 2020 Valentina Prevolnik Rupel et al., published by Sciendo

This work is licensed under the Creative Commons Attribution-NonCommercial-NoDerivatives 3.0 License.

Figure 1

Figure 2

Figure 3

Comparison of the Slovenian EQ-5D-3L and Slovenian EQ-5D-5L crosswalk value sets.

Selected health states, 3L and 5L values.

Crosswalk EQ-5D-5L Value Set for Slovenia

Article Category: Original scientific article

Published Online: Jun 25, 2020

Page range: 189 - 194

Received: Apr 04, 2020

Accepted: Jun 09, 2020

DOI: https://doi.org/10.2478/sjph-2020-0024

KeywordsEuroQol, EQ-5D-5L, interim value set, health-related quality of life, patient-reported outcomes

© 2020 Valentina Prevolnik Rupel et al., published by Sciendo

This work is licensed under the Creative Commons Attribution-NonCommercial-NoDerivatives 3.0 License.

Figure 1

Figure 2

Figure 3

Comparison of the Slovenian EQ-5D-3L and Slovenian EQ-5D-5L crosswalk value sets.

Selected health states, 3L and 5L values.

Keywords
EuroQol, EQ-5D-5L, interim value set, health-related quality of life, patient-reported outcomes