Ubiquinone Plasma Levels are Correlated with Brain Natriuretic Peptide Plasma Levels in Patients with Chronic Heart Failure: The Potential of Coenzyme Q10 Combined Therapy

1. Go AS, Mozaffarian D, Roger VL, et al. Heart disease and stroke statistics 2014 update: a report from the American Heart Association. American Heart Association Statistics Committee and Stroke Statistics Subcommittee. Circulation 2014; 129: 280-292.Search in Google Scholar

2. Ho KK, Pinsky JL, Kannel WB, et al. The epidemiology of heart failure: the Framingham Study. J Am Coll Cardiol 1993; 22: 6–13.10.1016/0735-1097(93)90455-AOpen DOISearch in Google Scholar

3. McMurray JJ, Adamopuulus S, Anker SD, et al. ESC Guidelines for the diagnosis and treatment of acute and chronic heart failure 2012: The Task Force for the Diagnosis and Treatment of Acute and Chronic Heart Failure 2012 of the European Society of Cardiology Deloped in collaboration with the Heart Failure Association (HFA) of the ESC. Eur Heart J 2012; 33: 1787–847.10.1093/eurheartj/ehs104Search in Google Scholar

4. Yancy CW, Jessup M, Bozkurt B, et al. ACCF/AHA Guideline for the management of heart failure: a report of the American College of Cardiology Foundation/American Heart Association task force on practice guidelines. Circulation 2013; 128: 240-327.10.1161/CIR.0b013e31829e8776Search in Google Scholar

5. Aronov DM. Importance of coenzyme Q10 in cardiology. Russian Medical Journal, 2007; 15: 1484-1488.Search in Google Scholar

6. Fotino AD, Thompson-Paul AM, Bazzano LA. Effect of coenzyme Q10 supplementation on heart failure: a meta-analysis. Am J Clin Nutr 2013; 97: 268–275.10.3945/ajcn.112.040741Search in Google Scholar

7. Mortensen SA. Coenzyme Q10: will this natural substance become a guideline-directed adjunctive therapy in heart failure? JACC Heart Fail 2015; 3:270-271.10.1016/j.jchf.2014.12.006Search in Google Scholar

8. Miles MV, Horn PS, Tang PH, et al. Age-related changes in plasma coenzyme Q10 concentrations and redox state in apparently healthy children and adults. AJ Clin Chim Acta 2004; 347: 139-144.10.1016/j.cccn.2004.04.003Search in Google Scholar

9. Medvedev OS, Kalenikova EI, Gorodetzkaya EA, et al. Coenzyme Q10 in cardiology practice – theoretical bases and clinical studies results. Russian Medical Journal, 2009; 17: 1177-1181.Search in Google Scholar

10. R. Ferrari, L. Agnoletti, L. Comini, G. et al. Oxidative stress during myocardial ischemia and heart failure, Eur Heart J 1998; 19:2–11.Search in Google Scholar

11. Sarah L. Molyneux, Christopher M, et al. Coenzyme Q10 An Independent Predictor of Mortality in Chronic Heart Failure Christchurch, New Zealand. J Am Coll Caqrdiol 2008; 52: 1435-1441.Search in Google Scholar

12. Madamanchi NR, Runge MS. Mitochondrial dysfunction in atherosclerosis. Circ Res. 2007; 100: 460–473.10.1161/01.RES.0000258450.44413.96Open DOISearch in Google Scholar

13. Ponikowski P, Voors AA, Anker SD et al. 2016 ESC Guidelines for the diagnosis and treatment of acute and chronic heart failure: The Task Force for the diagnosis and treatment of acute and chronic heart failure of the European Society of Cardiology. Developed with the special contribution of the Heart Failure Association (HFA) of the ESC. Eur Heart J 2016, 20.10.1093/eurheartj/ehw128Search in Google Scholar

14. Berezin AE. Biological markers in chronic heart failure: hopes, reality, perspectives. Serceva nedostatnist 2013; 1:5-15.Search in Google Scholar

15. Tsutamoto T. Plasma brain natriuretic peptide level as a biochemical marker of morbidity and mortality in patients with asymptomatic or minimally symptomatic left ventricular dysfunction. Comparison with plasma angiotensin II and endothelin-1. Eur Heart J 199; 20: 1799-1807.10.1053/euhj.1999.1746Search in Google Scholar

16. Soja AM, Mortensen SA. Treatment of congestive heart failure with coenzyme Q 10 illuminated by meta-analyses of clinical trials. Mol Aspects Med 1997; 18: 159–168.10.1016/S0098-2997(97)00042-3Search in Google Scholar

17. Sander S, Coleman CI, Patel AA, et al. The impact of coenzyme Q10 on systolic function in patients with chronic heart failure. J Card Fail 2006; 12: 464–472.10.1016/j.cardfail.2006.03.00716911914Search in Google Scholar

18. Judy WV, Hall JH, Toth PD, et al. Double blind-double crossover study of coenzyme Q10 in heart failure, in: Biomedical and Clinical Aspects of Coenzyme Q, Vol. 5. K. Folkers and Y. Yamamura, eds, Elsevier, Amsterdam 1986, pp. 315–323.Search in Google Scholar

19. Munkholm H, Hansen HHT, Rasmussen K. Coenzyme Q10 treatment in serious heart failure. Ann Intern Med 1999; 9: 285–289.10.1002/biof.5520090225Search in Google Scholar

20. Wolsk E, Claggett B, Pfeffer MA, et al. Role of B-Type Natriuretic Peptide and N-Terminal Prohormone BNP as Predictors of Cardiovascular Morbidity and Mortality in Patients With a Recent Coronary Event and Type 2 Diabetes Mellitus. J Am Heart Assoc. 2017; 6: 43-47.10.1161/JAHA.116.004743566914628554908Search in Google Scholar

21. Edlund PO. Determination of coenzyme Q10, α-tocopherol and cholesterol in biological samples by coupled-column liquid chromatography with coulometric and ultraviolet detection. J Chromatogr 1988; 425: 87–97.10.1016/0378-4347(88)80009-4Search in Google Scholar

22. Rosenfeldt FL, Haas SJ, Krum H, et al. Coenzyme Q10 in the treatment of hypertension: a meta-analysis of the clinical trials. J Hum Hypertens 2007; 21:297-306.10.1038/sj.jhh.1002138Search in Google Scholar

23. Gorokhova SG, Sizova ZM. Pharmacotherapy of chronic heart failure in ambulatory practice. Physician’s workbook. Medpraktika-M 2008; pp.85.Search in Google Scholar

24. Mortensen SA, Rosenfeldt F, Kumar A, et al. The effect of coenzyme Q10 on morbidity and mortality in chronic heart failure: results from Q-SYMBIO: a randomized double-blind trial. JACC Heart Fail. 2014; 2:641–649.10.1016/j.jchf.2014.06.008Search in Google Scholar

25. Keogh A, Fenton S, Leslie C, et al. Randomized doubleblind, placebo-controlled trial of coenzyme Q10 therapy in class II and III systolic heart failure. Heart Lung Circ. 2003; 12:135–141.10.1046/j.1443-9506.2003.00189.xSearch in Google Scholar

26. DiNicolantonio JJ, Bhutani J, McCarty MF, et al. Coenzyme Q10 for the treatment of heart failure: a review of the literature. Open Heart 2015; 2: 32-36.10.1136/openhrt-2015-000326Search in Google Scholar

27. Alehagen U, Johansson P, Bjornstedt M, et al. Cardiovascular mortality and N-terminal-proBNP reduced after combined selenium and coenzyme Q10 supplementation: a 5-year prospective randomized doubleblind placebo-controlled trial among elderly Swedish citizens. Int J Cardiol. 2013; 167:1860-1866.10.1016/j.ijcard.2012.04.156Search in Google Scholar

28. Sizova ZM, Farafoniva TN, Medvedev OS, et al. Possibilities of different doses coenzyme Q10 administration in patients with chronic heart failure. Heart failure 2010; 11: 218-222.Search in Google Scholar

29. Tokareva OG, Kharitonova EV, Mareev VY, et al. Vliyanie koenzima Q10 v sostave standartnoj terapii bolnyx xronicheskoj serdechnoj nedostatochnostyu na plazmennye urovni mozgovogo natrijureticheskogo peptida. Zhurnal Serdechnaya Nedostatochnost 2014; 850: 232–237.Search in Google Scholar

30. Jankowski J, Korzeniowska K, Cieslewicz A, et al. Coenzyme Q10 - A new player in the treatment of heart failure? Pharmacol Rep 2016; 68: 1015-1019.10.1016/j.pharep.2016.05.012Search in Google Scholar

31. Lampertico M, Comis S. Italian multicenter study on the efficacy and safety of coenzyme Q10 as adjuvant therapy in heart failure. Clin Investig. 1993; 71: 129-133.10.1007/BF00226853Search in Google Scholar

32. Fotino AD, Thompson-Paul AM, Bazzano LA. Effect of coenzyme Q10 supplementation on heart failure: a meta-analysis. Am J Clin Nutr 2013; 97: 268-75.10.3945/ajcn.112.040741Search in Google Scholar

33. Morisco C, Trimarco B, Condorelli M. Effect of coenzyme Q10 therapy in patients with congestive heart failure: a long-term multicenter randomized study. Clin Investig. 1993; 71: 134–136.10.1007/BF00226854Search in Google Scholar

34. Crane FL, Hatefi Y, Lester RL, et al. Isolation of a quinone from beef heart mitochondria. Biochim Biophys Acta 1957; 25: 220–1.10.1016/0006-3002(57)90457-2Open DOISearch in Google Scholar

35. Mellors A, Tappel AL. The inhibition of mitochondrial peroxidation by ubiquinone and ubiquinol. J Biol Chem 1966; 241: 4353–4356.10.1016/S0021-9258(18)99728-0Search in Google Scholar