<abstract xmlns="http://www.w3.org/1999/xhtml"><p>Leprosy is a disease that is caused by <italic>Mycobacterium leprae</italic> which results in lots of disabilities in the patients. Leprosy is treated by multi-drug therapy regimen; however, this therapy might cause leprosy reactions in the patients. There are several types of lepromatous reaction: type 1 reaction, type 2 reaction and neuritis. Type 1 reaction mainly occurs in BB, BL and BT forms of leprosy and is characterized by exacerbation of preexisting lesions. The therapy of this reaction according to the WHO guideline is corticosteroid therapy. This article will explain several key points related to the corticosteroid therapy in leprosy reversal reactions, including the side effects and alternative therapies available.</p></abstract>

Leprosy is a disease that is caused by Mycobacterium leprae which results in lots of disabilities in the patients. Leprosy is treated by multi-drug therapy regimen; however, this therapy might cause leprosy reactions in the patients. There are several types of lepromatous reaction: type 1 reaction, type 2 reaction and neuritis. Type 1 reaction mainly occurs in BB, BL and BT forms of leprosy and is characterized by exacerbation of preexisting lesions. The therapy of this reaction according to the WHO guideline is corticosteroid therapy. This article will explain several key points related to the corticosteroid therapy in leprosy reversal reactions, including the side effects and alternative therapies available.

Glucocorticoids in Leprosy Reversal reaction

Department of Dermatology and Venereology

Serbian Journal of Dermatology and Venereology

This work is licensed under the Creative Commons Attribution-NonCommercial-NoDerivatives 4.0 License.

{"article-title":"Glucocorticoids in Leprosy Reversal reaction"}

Leprosy is a disease that is caused by Mycobacterium leprae which results in lots of disabilities in the patients. Leprosy is treated by multi-drug therapy...

Glucocorticoids in Leprosy Reversal reaction

Published Online: Feb 20, 2020

Page range: 77 - 83

Received: Feb 26, 2019

Accepted: Mar 10, 2019

DOI: https://doi.org/10.2478/sjdv-2019-0011

Keywords
Leprosy, Gene Expression Profiling, Glucocorticoids, Comorbidity, Diagnosis, Prednisolone, Indonesia

© 2019 Renni Yuniati et al., published by Sciendo

This work is licensed under the Creative Commons Attribution-NonCommercial-NoDerivatives 4.0 License.

Glucocorticoids in Leprosy Reversal reaction

Published Online: Feb 20, 2020

Page range: 77 - 83

Received: Feb 26, 2019

Accepted: Mar 10, 2019

DOI: https://doi.org/10.2478/sjdv-2019-0011

KeywordsLeprosy, Gene Expression Profiling, Glucocorticoids, Comorbidity, Diagnosis, Prednisolone, Indonesia

© 2019 Renni Yuniati et al., published by Sciendo

This work is licensed under the Creative Commons Attribution-NonCommercial-NoDerivatives 4.0 License.

Keywords
Leprosy, Gene Expression Profiling, Glucocorticoids, Comorbidity, Diagnosis, Prednisolone, Indonesia