<abstract xmlns="http://www.w3.org/1999/xhtml"><p>Basal cell carcinoma is the most common form of cutaneous cancer. In majority of cases it is locally invasive with slow growth, ranging in size from a couple of milimeters to a couple of centimeters and located primarily on sun-exposed regions. Giant basal cell carcinoma, defined as a tumor that is larger than 5 cm in diameter, is a very rare type of cutaneous malignancy accounting for 0.5-1% of all basal cell carcinomas. We present a case of a 74-year-old man with a 17 x 14 cm giant basal cell carcinoma in the right supraclavicular region. Detailed history revealed that the lesion had started as a papule 15 years before presentation. Despite its growth, the lesion was neglected until admission. Histological examination of skin lesion confirmed superficial and focally infiltrative types of basal cell carcinoma. Electron radiotherapy was administered with 54 Gy total dose delivered in 20 daily fractions which resulted in healing of lesions and adequate response. Thus, definitive radiotherapy can be just as effective as excision when the criteria are met.</p></abstract>

Basal cell carcinoma is the most common form of cutaneous cancer. In majority of cases it is locally invasive with slow growth, ranging in size from a couple of milimeters to a couple of centimeters and located primarily on sun-exposed regions. Giant basal cell carcinoma, defined as a tumor that is larger than 5 cm in diameter, is a very rare type of cutaneous malignancy accounting for 0.5-1% of all basal cell carcinomas. We present a case of a 74-year-old man with a 17 x 14 cm giant basal cell carcinoma in the right supraclavicular region. Detailed history revealed that the lesion had started as a papule 15 years before presentation. Despite its growth, the lesion was neglected until admission. Histological examination of skin lesion confirmed superficial and focally infiltrative types of basal cell carcinoma. Electron radiotherapy was administered with 54 Gy total dose delivered in 20 daily fractions which resulted in healing of lesions and adequate response. Thus, definitive radiotherapy can be just as effective as excision when the criteria are met.

Giant Basal Cell Carcinoma – a Case Report

Clinic of Dermatovenereology, Clinical Center of Serbia

Department of Dermatovenereology, School of Medicine

Institute of Pathology, School of Medicine

Serbian Journal of Dermatology and Venereology

This work is licensed under the Creative Commons Attribution-NonCommercial-NoDerivatives 4.0 License.

{"article-title":"Giant Basal Cell Carcinoma \u2013 a Case Report"}

Basal cell carcinoma is the most common form of cutaneous cancer. In majority of cases it is locally invasive with slow growth, ranging in size from a couple...

Giant Basal Cell Carcinoma – a Case Report

Published Online: Feb 14, 2019

Page range: 83 - 89

Received: Nov 05, 2018

Accepted: Dec 03, 2018

DOI: https://doi.org/10.2478/sjdv-2018-0012

Keywords
Carcinoma, Basal Cell, Diagnosis, Neoplasm Metastasis, Skin, Radiotherapy, Biopsy, Treatment Outcome, Case Reports

© 2018 Igor Kapetanović et al., published by Sciendo

This work is licensed under the Creative Commons Attribution-NonCommercial-NoDerivatives 4.0 License.

Giant Basal Cell Carcinoma – a Case Report

Published Online: Feb 14, 2019

Page range: 83 - 89

Received: Nov 05, 2018

Accepted: Dec 03, 2018

DOI: https://doi.org/10.2478/sjdv-2018-0012

KeywordsCarcinoma, Basal Cell, Diagnosis, Neoplasm Metastasis, Skin, Radiotherapy, Biopsy, Treatment Outcome, Case Reports

© 2018 Igor Kapetanović et al., published by Sciendo

This work is licensed under the Creative Commons Attribution-NonCommercial-NoDerivatives 4.0 License.

Keywords
Carcinoma, Basal Cell, Diagnosis, Neoplasm Metastasis, Skin, Radiotherapy, Biopsy, Treatment Outcome, Case Reports