<abstract xmlns="http://www.w3.org/1999/xhtml">We present a case of probably unreported aortic stenosis evolution in a patient with primary antiphospholipid syndrome (APS). A female patient, 54 years old, with a history of recurrent deep venous thrombosis, an episode of pulmonary embolism and was positive for APS antibodies. She was kept on warfarin and aspirin. The patient was admitted with acute pulmonary edema and severe aortic stenosis. While preparing for aortic valve surgery, the patient developed acute stroke, and a week later developed concurrent acute ischemia of both lower limbs. Emergency surgery salvaged the lower limbs and follow up transthoracic echocardiography showed marked regression of the thickening of the aortic valve leaflets, only mild aortic stenosis and moderate aortic regurgitation. Aortic valve surgery was cancelled, and the patient was kept on warfarin and aspirin.<bold>Conclusion</bold>Development of severe aortic stenosis is uncommon in primary APS, and this scenario of spontaneous improvement from a severe to a mild aortic stenosis, is probably unreported before.</abstract>

We present a case of probably unreported aortic stenosis evolution in a patient with primary antiphospholipid syndrome (APS). A female patient, 54 years old, with a history of recurrent deep venous thrombosis, an episode of pulmonary embolism and was positive for APS antibodies. She was kept on warfarin and aspirin. The patient was admitted with acute pulmonary edema and severe aortic stenosis. While preparing for aortic valve surgery, the patient developed acute stroke, and a week later developed concurrent acute ischemia of both lower limbs. Emergency surgery salvaged the lower limbs and follow up transthoracic echocardiography showed marked regression of the thickening of the aortic valve leaflets, only mild aortic stenosis and moderate aortic regurgitation. Aortic valve surgery was cancelled, and the patient was kept on warfarin and aspirin.ConclusionDevelopment of severe aortic stenosis is uncommon in primary APS, and this scenario of spontaneous improvement from a severe to a mild aortic stenosis, is probably unreported before.

Spontaneous regression of severe aortic stenosis after massive embolization in a patient with antiphospholipid syndrome

Seminars in Cardiovascular Medicine

This work is licensed under the Creative Commons Attribution-NonCommercial-NoDerivatives 3.0 License.

We present a case of probably unreported aortic stenosis evolution in a patient with primary antiphospholipid syndrome (APS). A female patient, 54 years old,...

Spontaneous regression of severe aortic stenosis after massive embolization in a patient with antiphospholipid syndrome

Published Online: Apr 01, 2019

Page range: 4 - 8

Received: Nov 23, 2018

Accepted: Feb 18, 2019

DOI: https://doi.org/10.2478/semcard-2019-0002

Keywords
antiphospholipid syndrome, aortic stenosis, embolization

© 2019 Ali Youssef et al., published by Sciendo

This work is licensed under the Creative Commons Attribution-NonCommercial-NoDerivatives 3.0 License.

Spontaneous regression of severe aortic stenosis after massive embolization in a patient with antiphospholipid syndrome

Published Online: Apr 01, 2019

Page range: 4 - 8

Received: Nov 23, 2018

Accepted: Feb 18, 2019

DOI: https://doi.org/10.2478/semcard-2019-0002

Keywordsantiphospholipid syndrome, aortic stenosis, embolization

© 2019 Ali Youssef et al., published by Sciendo

This work is licensed under the Creative Commons Attribution-NonCommercial-NoDerivatives 3.0 License.

Keywords
antiphospholipid syndrome, aortic stenosis, embolization