<abstract xml:lang="en" xmlns="http://www.w3.org/1999/xhtml"><p>The aim of the present experiment was to assess the clinical, haematological, biochemical and immunological responses of pigs experimentally infected with Trichinella spiralis. One group of 6 pigs was infected with 1500 larvae/kg body weight and one group of 7, was maintained as control. The highest larval density was in the diaphragm (504.3 ± 8.2). During the experimental T. spiralis infection in pigs, increased values of total granulocyte number, eosinophils, blood glucose, K+ concentration, CK, ALT, AST and ALP were registered in different stages of infection. A slight increase of the phagocytic activity was registered 14 days p.i., in the infected group. Significantly increased values in lymphocyte activity, in infected group, was observed 30 and 60 days p.i. comparative with control. The specific IgG antibodies were detectable by ELISA at 14 days p.i. The results obtained in this study provide a better understanding about complete interactions occurring during Trichinella infection in pigs.</p></abstract>

The aim of the present experiment was to assess the clinical, haematological, biochemical and immunological responses of pigs experimentally infected with Trichinella spiralis. One group of 6 pigs was infected with 1500 larvae/kg body weight and one group of 7, was maintained as control. The highest larval density was in the diaphragm (504.3 ± 8.2). During the experimental T. spiralis infection in pigs, increased values of total granulocyte number, eosinophils, blood glucose, K+ concentration, CK, ALT, AST and ALP were registered in different stages of infection. A slight increase of the phagocytic activity was registered 14 days p.i., in the infected group. Significantly increased values in lymphocyte activity, in infected group, was observed 30 and 60 days p.i. comparative with control. The specific IgG antibodies were detectable by ELISA at 14 days p.i. The results obtained in this study provide a better understanding about complete interactions occurring during Trichinella infection in pigs.

Characterization of host-parasite interactions during the experimental Trichinella spiralis infection in pigs

Department of Parasitology and Parasitic Diseases, University of Agricultural Sciences and Veterinary Medicine Cluj-Napoca, Calea Mănăştur 3 - 5, Cluj-Napoca, 400372, Romania

Helminthologia

This work is licensed under the Creative Commons Attribution-NonCommercial-NoDerivatives 3.0 License.

The aim of the present experiment was to assess the clinical, haematological, biochemical and immunological responses of pigs experimentally infected with...

Characterization of host-parasite interactions during the experimental Trichinella spiralis infection in pigs

Published Online: Aug 03, 2012

Page range: 139 - 146

DOI: https://doi.org/10.2478/s11687-012-0029-7

Keywords
Trichinella spiralis, RCI, phagocytosis, blastic transformation, ELISA

© 2012 Institute of Parasitology, SAS, Košice, Slovakia

This work is licensed under the Creative Commons Attribution-NonCommercial-NoDerivatives 3.0 License.

Characterization of host-parasite interactions during the experimental Trichinella spiralis infection in pigs

Published Online: Aug 03, 2012

Page range: 139 - 146

DOI: https://doi.org/10.2478/s11687-012-0029-7

KeywordsTrichinella spiralis, RCI, phagocytosis, blastic transformation, ELISA

© 2012 Institute of Parasitology, SAS, Košice, Slovakia

This work is licensed under the Creative Commons Attribution-NonCommercial-NoDerivatives 3.0 License.

Keywords
Trichinella spiralis, RCI, phagocytosis, blastic transformation, ELISA