Phenotypic and genotypic evaluation of adherence and biofilm development in Candida albicans respiratory tract isolates from hospitalized patients

1. Calderone RA, Fonzi WA. Virulence factors of Candida albicans. Trends Microbiol. 2001;9(7):327-35. DOI: 10.1016/S0966-842X(01)02094-710.1016/S0966-842X(01)02094-7Open DOISearch in Google Scholar

2. Cirpaciu D, Goanţă CM, Tusaliu M, Curutiu C, Budu V. Microbial etiology of acute otitis externa-a one year study. Rom Biotech Lett. 2017;22(1):12316.Search in Google Scholar

3. Fanello S, Bouchara J, Sauteron M, Delbos V, Parot E, Marot-Leblond A, et al. Predictive value of oral colonization by Candida yeasts for the onset of a nosocomial infection in elderly hospitalized patients. J Med Micro-biol. 2006;55(2):223-8. DOI: 10.1099/jmm.0.46155-010.1099/jmm.0.46155-016434716Search in Google Scholar

4. Wisplinghoff H, Bischoff T, Tallent SM, Seifert H, Wenzel RP, Edmond MB. Nosocomial bloodstream infections in US hospitals: analysis of 24,179 cases from a prospective nationwide surveillance study. Clin Infect Dis. 2004;39(3):309-17. DOI: 10.1086/42194610.1086/42194615306996Open DOISearch in Google Scholar

5. Grimoud AM, Marty N, Bocquet H, Andrieu S, Lodter JP, Chabanon G. Colonization of the oral cavity by Candida species: risk factors in long-term geriatric care. J Oral Sci. 2003;45(1):51-5. DOI: 10.2334/josnusd.45.5110.2334/josnusd.45.5112816366Open DOISearch in Google Scholar

6. Dongari-Bagtzoglou A, Dwivedi P, Ioannidou E, Shaqman M, Hull D, Burleson J. Oral Candida infection and colonization in solid organ transplant recipients. Oral Microbiol Immun. 2009;24(3):249-54. DOI: 10.1111/j.1399-302X.2009.00505.x10.1111/j.1399-302X.2009.00505.x269961019416456Open DOISearch in Google Scholar

7. Budtz‐Jörgensen E, Stenderup A, Grabowski M. An epidemiologic study of yeasts in elderly denture wearers. Community Dent Oral Epidemiol. 1975;3(3):115-9. DOI: 10.1111/j.1600-0528.1975.tb00291.x10.1111/j.1600-0528.1975.tb00291.x1056815Open DOISearch in Google Scholar

8. Shimizu C, Kuriyama T, Williams DW, Karasawa T, Inoue K, Nakagawa K, et al. Association of oral yeast carriage with specific host factors and altered mouth sensation. Oral Surg Oral Med Oral Patholo Oral Radiol Endod. 2008;105(4):445-51. DOI: 10.1016/j.tripleo.2007.11.03010.1016/j.tripleo.2007.11.03018329579Search in Google Scholar

9. Yano A, Abe A, Aizawa F, Yamada H, Minami K, Matsui M, et al. The effect of eating sea cucumber jelly on Candida load in the oral cavity of elderly individuals in a nursing home. Mar Drugs. 2013;11(12):4993-5007. DOI: 10.3390/md1112499310.3390/md11124993387789824335524Open DOISearch in Google Scholar

10. Cuéllar-Cruz M, López-Romero E, Villagómez-Castro JC, Ruiz-Baca E. Candida species: new insights into biofilm formation. Future Microbiol. 2012;7(6):755-71. DOI: 10.2217/fmb.12.4810.2217/fmb.12.4822702528Search in Google Scholar

11. Finkel JS, Mitchell AP. Genetic control of Candida albicans biofilm development. Nat Rev Microbiol. 2011;9(2):109. DOI: 10.1038/nrmicro247510.1038/nrmicro2475389158721189476Open DOISearch in Google Scholar

12. Harriott MM, Noverr MC. Importance of Candida – bacterial polymicrobial biofilms in disease. Trends Microbiol. 2011;19(11):557-63. DOI: 10.1016/j.tim.2011.07.00410.1016/j.tim.2011.07.004320527721855346Open DOISearch in Google Scholar

13. Mayer F, Wilson D, Hube B. Candida albicans pathogenicity mechanisms. Virulence 4: 119–128. 2013. DOI: 10.4161/viru.2291310.4161/viru.22913365461023302789Open DOISearch in Google Scholar

14. Georgescu M, Vrinceanu D, Radulescu L, Tusaliu M, Martu C, Curutiu C, et al. Microbial biofilms and implantable hearing aids. Rom Biotech Lette. 2017;22(4):12681-6.Search in Google Scholar

15. Ramage G, Rajendran R, Sherry L, Williams C. Fungal biofilm resistance. Int J Microbiol. 2012;2012.10.1155/2012/528521329932722518145Search in Google Scholar

16. Mathé L, Van Dijck P. Recent insights into Candida albicans biofilm resistance mechanisms. Curr Genet. 2013;59(4):251-64. DOI: 10.1007/s00294-013-0400-310.1007/s00294-013-0400-3382424123974350Open DOISearch in Google Scholar

17. Baillie GS, Douglas LI. Role of dimorphism in the development of Candida albicans biofilms. J Med Microbiol. 1999;48(7):671-9. DOI: 10.1099/00222615-48-7-67110.1099/00222615-48-7-67110403418Open DOISearch in Google Scholar

18. Ramage G, VandeWalle K, López-Ribot JL, Wickes BL. The filamentation pathway controlled by the Efg1 regulator protein is required for normal biofilm formation and development in Candida albicans. FEMS Microbiol lett. 2002;214(1):95-100. DOI: 10.1111/j.1574-6968.2002.tb11330.x10.1111/j.1574-6968.2002.tb11330.x12204378Open DOISearch in Google Scholar

19. Richard ML, Nobile CJ, Bruno VM, Mitchell AP. Candida albicans biofilm-defective mutants. Eukaryot Cell. 2005;4(8):1493-502. DOI: 10.1128/EC.4.8.1493-1502.200510.1128/EC.4.8.1493-1502.2005121453316087754Open DOISearch in Google Scholar

20. Bonhomme J, d’Enfert C. Candida albicans biofilms: building a heterogeneous, drug-tolerant environment. Curr Opin Microbiol. 2013;16(4):398-403. DOI: 10.1016/j.mib.2013.03.00710.1016/j.mib.2013.03.00723566895Open DOISearch in Google Scholar

21. Nobile CJ, Mitchell AP. Regulation of cell-surface genes and biofilm formation by the C. albicans transcription factor Bcr1p. Curr Biol. 2005;15(12):1150-5. DOI: 10.1016/j.cub.2005.05.04710.1016/j.cub.2005.05.04715964282Open DOISearch in Google Scholar

22. Nobile CJ, Andes DR, Nett JE, Smith Jr FJ, Yue F, Phan Q-T, et al. Critical role of Bcr1-dependent adhesins in C. albicans biofilm formation in vitro and in vivo. PLoS Pathog. 2006;2(7):e63. DOI: 10.1371/journal.ppat.002006310.1371/journal.ppat.0020063148717316839200Open DOISearch in Google Scholar

23. Nobile CJ, Nett JE, Andes DR, Mitchell AP. Function of Candida albicans adhesin Hwp1 in biofilm formation. Eukaryot Cell. 2006;5(10):1604-10. DOI: 10.1128/EC.00194-0610.1128/EC.00194-06159533717030992Search in Google Scholar

24. Ghannoum M, Elteen KA. Correlative relationship between proteinase production, adherence and pathogenicity of various strains of Candida albi-cans. J Med Vet Mycol. 1986;24(5):407-13. DOI: 10.1080/0268121868000062110.1080/026812186800006213537262Open DOISearch in Google Scholar

25. Abu-Elteen KH, Elkarmi AZ, Hamad M. Characterization of phenotype-based pathogenic determinants of various Candida albicans strains in Jordan. Jap J Infect Dis. 2001;54(6):229-36.Search in Google Scholar

26. Rosa EAR, Rached RN, Ignácio SA, Rosa RT, da Silva WJ, Yau JYY, et al. Phenotypic evaluation of the effect of anaerobiosis on some virulence attributes of Candida albicans. J Med Microbiol. 2008;57(10):1277-81. DOI: 10.1099/jmm.0.2008/001107-010.1099/jmm.0.2008/001107-018809558Search in Google Scholar

27. Pichová I, Pavlíčková L, Dostál J, Dolejší E, Hrušková‐ Heidingsfeldová O, Weber J, et al. Secreted aspartic proteases of Candida albicans, Candida tropicalis, Candida parapsilosis and Candida lusitaniae: inhibition with peptidomimetic inhibitors. Eur J Biochem. 2001;268(9):2669-77. DOI: 10.1046/j.1432-1327.2001.02152.x10.1046/j.1432-1327.2001.02152.x11322888Open DOISearch in Google Scholar

28. Borg M, Rüchel R. Expression of extracellular acid proteinase by proteolytic Candida spp. during experimental infection of oral mucosa. Infect Immun. 1988;56(3):626-31.10.1128/iai.56.3.626-631.19882593373277916Search in Google Scholar

29. El‐Maghrabi E, Dixon D, Burnett J. Characterization of Candida albicans epidermolytic proteases and their role in yeast‐cell adherence to keratinocytes. Clin Exp Dermatol. 1990;15(3):183-91. DOI: 10.1111/j.1365-2230.1990.tb02069.x10.1111/j.1365-2230.1990.tb02069.x2194713Open DOISearch in Google Scholar

30. Ollert M, Söhnchen R, Korting H, Ollert U, Bräutigam S, Bräutigam W. Mechanisms of adherence of Candida albicans to cultured human epidermal keratinocytes. Infect Immun. 1993;61(11):4560-8.10.1128/iai.61.11.4560-4568.19932812058406852Search in Google Scholar

31. Li F, Palecek SP. EAP1, a Candida albicans gene involved in binding human epithelial cells. Eukaryot Cell. 2003;2(6):1266-73. DOI: 10.1128/EC.2.6.1266-1273.200310.1128/EC.2.6.1266-1273.200332664614665461Open DOISearch in Google Scholar

32. Hazen K, Glee P. Cell surface hydrophobicity and medically important fungi. Curr Top Med Mycol. 1995;6:1.Search in Google Scholar

33. Hazen KC, Wu JG, Masuoka J. Comparison of the hydrophobic properties of Candida albicans and Candida dubliniensis. Infect Immun. 2001;69(2):779-86. DOI: 10.1128/IAI.69.2.779-786.200110.1128/IAI.69.2.779-786.20019795211159968Open DOISearch in Google Scholar

34. Telcian A, Mohammed DH, Chifiriuc M, Bleotu C, Holban A, Curutiu C, et al. Assessment of the anti-bio-film activity and biocompatibility of novel PE and PVC polymers. Rom Biotech Lett. 2017;22(5):12997.Search in Google Scholar

35. Stan T, Teodor ED, Gatea F, Chifiriuc C, Lazăr V. Antioxidant and antifungal activity of Romanian propolis. Rom Biotech Lett. 2017;22(6):12116-13124.Search in Google Scholar

36. Melo AS, Bizerra FC, Freymüller E, Arthington-Skaggs BA, Colombo AL. Biofilm production and evaluation of antifungal susceptibility amongst clinical Candida spp. isolates, including strains of the Candida parapsilosis complex. Med Mycol. 2011;49(3):253-62. DOI: 10.3109/13693786.2010.53003210.3109/13693786.2010.53003221039308Open DOISearch in Google Scholar

37. Hassan A, Usman J, Kaleem F, Omair M, Khalid A, Iqbal M. Evaluation of different detection methods of biofilm formation in the clinical isolates. Braz J Infect Dis. 2011;15(4):305-11. DOI: 10.1016/S1413-8670(11)70197-010.1016/S1413-8670(11)70197-0Open DOISearch in Google Scholar

38. Konkel ME, Joens LA. Adhesion to and invasion of HEp-2 cells by Campylobacter spp. Infect Immun. 1989;57(10):2984-90.10.1128/iai.57.10.2984-2990.19892607592550368Search in Google Scholar

39. Zhang Y, Zhang S, Liu X, Wen H, Wang M. A simple method of genomic DNA extraction suitable for analysis of bulk fungal strains. Lett Appl Microbiol. 2010;51(1):114-8. DOI: 10.1111/j.1472-765X.2010.02867.x10.1111/j.1472-765X.2010.02867.x20536704Search in Google Scholar

40. Bruder-Nascimento A, Camargo CH, Mondelli AL, Sugizaki MF, Sadatsune T, Bagagli E. Candida species biofilm and Candida albicans ALS3 polymorphisms in clinical isolates. Braz J Microbiol. 2014;45(4):1371-7. DOI: 10.1590/S1517-8382201400040003010.1590/S1517-83822014000400030Open DOISearch in Google Scholar

41. Soll DR. The ins and outs of DNA fingerprinting the infectious fungi. Clin Microbiol Rev. 2000;13(2):332-70. DOI: 10.1128/CMR.13.2.33210.1128/CMR.13.2.33210015610756003Open DOISearch in Google Scholar

42. Samaranayake Y, Dassanayake R, Cheung B, Jayati-lake J, Yeung K, Yau J, et al. Differential phospholipase gene expression by Candida albicans in artificial media and cultured human oral epithelium. APMIS. 2006;114(12):857-66. DOI: 10.1111/j.1600-0463.2006.apm_479.x10.1111/j.1600-0463.2006.apm_479.x17207086Open DOISearch in Google Scholar

43. Cho T, Hamatake H, Kaminishi H, Hagihara Y, Watanabe K. The relationship between cyclic adenosine 3′, 5′-monophosphate and morphology in exponential phase Candida albicans. J Med Vet Mycol. 1992;30(1):35-42. DOI: 10.1080/0268121928000005110.1080/02681219280000051Open DOISearch in Google Scholar

44. Ogasawara A, Odahara K, Toume M, Watanabe T, Mikami T, Matsumoto T. Change in the respiration system of Candida albicans in the lag and log growth phase. Biol Pharm Bull. 2006;29(3):448-50. DOI: 10.1248/bpb.29.44810.1248/bpb.29.44816508143Open DOISearch in Google Scholar

45. Abad‐Zapatero C, Goldman R, Muchmore SW, Hutchins C, Stewart K, Navaza J, et al. Structure of a secreted aspartic protease from C. albicans complexed with a potent inhibitor: implications for the design of antifungal agents. Protein Sci. 1996;5(4):640-52. DOI: 10.1002/pro.556005040810.1002/pro.556005040821433888845753Open DOISearch in Google Scholar

46. O’Connor L, Lahiff S, Casey F, Glennon M, Cormican M, Maher M. Quantification of ALS1 gene expression in Candida albicans biofilms by RT-PCR using hybridisation probes on the LightCycler™. Mol Cell Probes. 2005;19(3):153-62. DOI: 10.1016/j.mcp.2004.10.00710.1016/j.mcp.2004.10.00715797814Open DOISearch in Google Scholar

47. Cheng G, Wozniak K, Wallig MA, Fidel PL, Trupin SR, Hoyer LL. Comparison between Candida albi-cans agglutinin-like sequence gene expression patterns in human clinical specimens and models of vaginal candidiasis. Infect Immun. 2005;73(3):1656-63. DOI: 10.1128/IAI.73.3.1656-1663.200510.1128/IAI.73.3.1656-1663.2005106495515731066Open DOISearch in Google Scholar

48. Wang Y. Fungal adenylyl cyclase acts as a signal sensor and integrator and plays a central role in interaction with bacteria. PLoS Pathog. 2013;9(10):e1003612. DOI: 10.1371/journal.ppat.100361210.1371/journal.ppat.1003612379502624130478Search in Google Scholar