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Figure 1

Coverage probability (CovP) concept: an example case is shown to indicate CovP-internal target volume (ITV) and planning organ at risk volumes (PRVs).
Coverage probability (CovP) concept: an example case is shown to indicate CovP-internal target volume (ITV) and planning organ at risk volumes (PRVs).

Figure 2

Survival outcomes: Kaplan-Meier curves of biochemically no evidence of disease (bNED), overall survival (OS), distant metastasis-free survival (DMFS) and prostate-cancer specific survival (PCSS).
Survival outcomes: Kaplan-Meier curves of biochemically no evidence of disease (bNED), overall survival (OS), distant metastasis-free survival (DMFS) and prostate-cancer specific survival (PCSS).

Figure 3

Late genitourinary (GU) toxicity items Radiation Therapy Oncology Group (RTOG) bladder late, common terminology criteria (CTC) urinary frequency and CTC urinary obstruction scored over the follow up (FU) period (left).Y-axis: percentage of patients reporting the toxicity item. Top X-axis: number n of patients with data available. Lower X-axis: years after radiotherapy. Right column: maximum late toxicity summed up by grade
Late genitourinary (GU) toxicity items Radiation Therapy Oncology Group (RTOG) bladder late, common terminology criteria (CTC) urinary frequency and CTC urinary obstruction scored over the follow up (FU) period (left).Y-axis: percentage of patients reporting the toxicity item. Top X-axis: number n of patients with data available. Lower X-axis: years after radiotherapy. Right column: maximum late toxicity summed up by grade

Figure 4

Late gastrointestinal (GI) toxicity items Radiation Therapy Oncology Group (RTOG) rectum late, common terminology criteria (CTC) proctitis and CTC rectal hemorrhage scored over the follow up (FU) period (left).Y-axis: percentage of patients reporting the toxicity item. Top X-axis: Number n of patients with data available. Lower X-axis: years after radiotherapy. Right column: maximum late toxicity summed up by grade.
Late gastrointestinal (GI) toxicity items Radiation Therapy Oncology Group (RTOG) rectum late, common terminology criteria (CTC) proctitis and CTC rectal hemorrhage scored over the follow up (FU) period (left).Y-axis: percentage of patients reporting the toxicity item. Top X-axis: Number n of patients with data available. Lower X-axis: years after radiotherapy. Right column: maximum late toxicity summed up by grade.

Patient characteristics of the study cohort

ParameterMean (min.- max.)Mediann (%)
Age at treatment (years)70 (56–83)70
Duration of radiotherapy (weeks)7.9 (7.4–8.7)7.9
Gleason-Score (n, %)
             64 (14.3 %)
             7a (3+4)15 (53.6 %)
             7b (4+3)9 (32.1 %)
cTNM (n, %)
             cT1c8 (28.6 %)
             cT2a8 (28.6 %)
             cT2b3 (10.7 %)
             cT2c9 (32.1 %)
Neoadjuvant ADT (n, %)22 (78.6 %)
             Duration of ADT (months, range)8.9 (3.0–27.0)6.0
             Initial PSA peak in ng/ml (range)9.1 (1.9–19.8)8.3
PSA-peak by subgroup
             0 < x ≤ 53 (10.7 %)
             5 < x ≤ 1015 (53.6 %)
             10 < x ≤ 158 (28.6 %)
             15 < x ≤ 202 (7.1 %)
eISSN:
1581-3207
Language:
English
Publication timeframe:
4 times per year
Journal Subjects:
Medicine, Clinical Medicine, Internal Medicine, Haematology, Oncology, Radiology