Ultrasonographic changes in the liver tumors as indicators of adequate tumor coverage with electric field for effective electrochemotherapy

1 Miklavcic D, Davalos RV. Electrochemotherapy (ECT) and irreversible electroporation (IRE) -advanced techniques for treating deep-seated tumors based on electroporation. Biomed Eng Online 2015; 14: I1. 10.1186/1475-925X-14-S3-I1MiklavcicDDavalosRVElectrochemotherapy (ECT) and irreversible electroporation (IRE) -advanced techniques for treating deep-seated tumors based on electroporationBiomed Eng Online201514I110.1186/1475-925X-14-S3-I1Open DOISearch in Google Scholar

2 Edhemovic I, Brecelj E, Gasljevic G, Marolt Music M, Gorjup V, Mali B, et al. Intraoperative electrochemotherapy of colorectal liver metastases. J Surg Oncol 2014; 110: 320-7. 10.1002/jso.23625EdhemovicIBreceljEGasljevicGMaroltMusic MGorjupVMaliBet alIntraoperative electrochemotherapy of colorectal liver metastasesJ Surg Oncol2014110320–710.1002/jso.23625Open DOISearch in Google Scholar

3 Rubinsky B. Irreversible electroporation in medicine. Technol Cancer Res Treat 2007; 6: 255-60. 10.1007/978-3-642-05420-4RubinskyBIrreversible electroporation in medicineTechnol Cancer Res Treat20076255–6010.1007/978-3-642-05420-4Open DOISearch in Google Scholar

4 Chapiro J, Geschwind J-F. Science to practice: systemic implications of ablative tumor therapies - reality uncovered and myths exposed? Radiology 2016; 280: 329-31. 10.1148/radiol.2016160505ChapiroJGeschwindJ-FScience to practice: systemic implications of ablative tumor therapies - reality uncovered and myths exposed? Radiology2016280329–3110.1148/radiol.2016160505Open DOISearch in Google Scholar

5 Coletti L, Battaglia V, De Simone P, Turturici L, Bartolozzi C, Filipponi F. Safety and feasibility of electrochemotherapy in patients with unresectable colorectal liver metastases: a pilot study. Int J Surg 2017; 44: 26-32. 10.1016/j.ijsu.2017.06.033ColettiLBattagliaVDeSimone PTurturiciLBartolozziCFilipponiFSafety and feasibility of electrochemotherapy in patients with unresectable colorectal liver metastases: a pilot studyInt J Surg20174426–3210.1016/j.ijsu.2017.06.033Open DOISearch in Google Scholar

6 Campana LG, Clover AJP, Valpione S, Quaglino P, Gehl J, Kunte C, et al. Recommendations for improving the quality of reporting clinical electro-chemotherapy studies based on qualitative systematic review. Radiol Oncol 2016; 50: 1-13. 10.1515/raon-2016-0006CampanaLGCloverAJPValpioneSQuaglinoPGehlJKunteCet alRecommendations for improving the quality of reporting clinical electro-chemotherapy studies based on qualitative systematic reviewRadiol Oncol2016501–1310.1515/raon-2016-0006Open DOISearch in Google Scholar

7 Yarmush ML, Golberg A, Serša G, Kotnik T, Miklavčič D. Electroporation-based technologies for medicine: principles, applications, and challenges. Annu Rev Biomed Eng 2014; 16: 295-320. 10.1146/annurev-bio-eng-071813-104622YarmushMLGolbergASeršaGKotnikTMiklavčičDElectroporation-based technologies for medicine: principles, applications, and challengesAnnu Rev Biomed Eng201416295–32010.1146/annurev-bio-eng-071813-104622Open DOISearch in Google Scholar

8 Chunlan J, Davalos RV, Bischof JC. A review of basic to clinical studies of irreversible electroporation therapy. Biomed Eng IEEE Trans 2015; 62: 4-20. 10.1109/TBME.2014.2367543ChunlanJDavalosRVBischofJCA review of basic to clinical studies of irreversible electroporation therapyBiomed Eng IEEE Trans2015624–2010.1109/TBME.2014.2367543Open DOISearch in Google Scholar

9 Miklavčič D, Mali B, Kos B, Heller R, Serša G. Electrochemotherapy: from the drawing board into medical practice. Biomed Eng Online 2014; 13: 29. 10.1186/1475-925X-13-29MiklavčičDMaliBKosBHellerRSeršaGElectrochemotherapy: from the drawing board into medical practiceBiomed Eng Online2014132910.1186/1475-925X-13-29Open DOISearch in Google Scholar

10 Edhemovic I. Electrochemotherapy: a new technological approach in treatment of metastases in the liver. Technol Cancer Res Treat 2011; 10: 475-85. 10.7785/tcrt.2012.500224EdhemovicIElectrochemotherapy: a new technological approach in treatment of metastases in the liverTechnol Cancer Res Treat201110475–8510.7785/tcrt.2012.500224Open DOISearch in Google Scholar

11 Edhemovic I, Brecelj E. Electrochemotherapy of liver tumors: colorectal liver metastasis. In: Vernier PT, Rubinsky B, Juergen F. Miklavcic D, Rols MP, Raso J, et al, editors. Handbook of electroporation Springer International Publishing; 2016. p. 1-12. 10.1007/978-3-319-26779-1_98-1EdhemovicIBreceljEElectrochemotherapy of liver tumors: colorectal liver metastasisVernier PT, Rubinsky B, Juergen F. Miklavcic D, Rols MP, Raso J, et al, editors. Handbook of electroporationSpringer International Publishing20161–1210.1007/978-3-319-26779-1_98-1Open DOISearch in Google Scholar

12 Djokic M, Cemazar M, Popovic P, Kos B, Dezman R, Bosnjak M, et al. Electrochemotherapy as treatment option for hepatocellular carcinoma, a prospective pilot study. EJSO 2018; 44: 651-7. 10.1016/j. ejso.2018.01.090DjokicMCemazarMPopovicPKosBDezmanRBosnjakMet alElectrochemotherapy as treatment option for hepatocellular carcinoma, a prospective pilot studyEJSO201844651–710.1016/j.ejso.2018.01.090Open DOISearch in Google Scholar

13 Neal II RE, Cheung W, Kavnoudias H, Thomson KR. Spectrum of imaging and characteristics for liver tumors treated with irreversible electroporation. J Biomed Sci Eng 2012; 05: 813-8. 10.4236/jbise.2012.512A102NealII RECheungWKavnoudiasHThomsonKRSpectrum of imaging and characteristics for liver tumors treated with irreversible electroporationJ Biomed Sci Eng201205813–810.4236/jbise.2012.512A102Open DOISearch in Google Scholar

14 Zhang Y, Guo Y, Ragin AB, Lewandowski RJ, Yang G-Y, Nijm GM, et al. MR Imaging to assess immediate response to irreversible electroporation for targeted ablation of liver tissues: Preclinical feasibility studies in a rodent model. Radiology 2010; 256: 424-32. 10.1148/radiol.10091955ZhangYGuoYRaginABLewandowskiRJYangG-YNijmGMet alMR Imaging to assess immediate response to irreversible electroporation for targeted ablation of liver tissues: Preclinical feasibility studies in a rodent modelRadiology2010256424–3210.1148/radiol.10091955Open DOISearch in Google Scholar

15 Kranjc M, Kranjc S, Bajd F, Serša G, Serša I, Miklavčič D. Predicting irreversible electroporation-induced tissue damage by means of magnetic resonance electrical impedance tomography. Sci Rep 2017; 7: 10323. 10.1038/ s41598-017-10846-5KranjcMKranjcSBajdFSeršaGSeršaIMiklavčičDPredicting irreversible electroporation-induced tissue damage by means of magnetic resonance electrical impedance tomographySci Rep201771032310.1038/s41598-017-10846-5Open DOISearch in Google Scholar

16 Kranjc M, Markelc B, Bajd F, Čemažar M, Serša I, Blagus T, et al. In situ monitoring of electric field distribution in mouse tumor during electroporation. Radiology 2015; 274: 115-23. 10.1148/radiol.14140311KranjcMMarkelcBBajdFČemažarMSeršaIBlagusTet alIn situ monitoring of electric field distribution in mouse tumor during electroporationRadiology2015274115–2310.1148/radiol.14140311Open DOISearch in Google Scholar

17 Miklavcic D, Corovic S, Pucihar G, Pavselj N. Importance of tumour coverage by sufficiently high local electric field for effective electrochemotherapy. EJC Supplements 2006; 4: 45-51. 10.1016/j.ejcsup.2006.08.006MiklavcicDCorovicSPuciharGPavseljNImportance of tumour coverage by sufficiently high local electric field for effective electrochemotherapyEJC Supplements2006445–5110.1016/j.ejcsup.2006.08.006Open DOISearch in Google Scholar

18 Miklavcic D, Snoj M, Zupanic A, Kos B, Cemazar M, Kropivnik M, et al. Towards treatment planning and treatment of deep-seated solid tumors by electrochemotherapy. Biomed Eng Online 2010; 9: 10. 10.1186/1475-925X-9-10MiklavcicDSnojMZupanicAKosBCemazarMKropivnikMet alTowards treatment planning and treatment of deep-seated solid tumors by electrochemotherapyBiomed Eng Online201091010.1186/1475-925X-9-10Open DOISearch in Google Scholar

19 Marčan M, Kos B, Miklavčič D. Effect of blood vessel segmentation on the outcome of electroporation-based treatments of liver tumors. PLoS One 2015; 10: e0125591. 10.1371/journal.pone.0125591MarčanMKosBMiklavčičDEffect of blood vessel segmentation on the outcome of electroporation-based treatments of liver tumorsPLoS One201510e012559110.1371/journal.pone.0125591Open DOISearch in Google Scholar

20 Marčan M, Pavliha D, Kos B, Forjanič T, Miklavčič D. Web-based tool for visualization of electric field distribution in deep-seated body structures and planning of electroporation-based treatments. Biomed Eng Online 2015; 14 Suppl 3: S4. 10.1186/1475-925X-14-S3-S4MarčanMPavlihaDKosBForjaničTMiklavčičDWeb-based tool for visualization of electric field distribution in deep-seated body structures and planning of electroporation-based treatmentsBiomed Eng Online2015143S410.1186/1475-925X-14-S3-S4Open DOISearch in Google Scholar

21 Zupanic A, Kos B, Miklavcic D. Treatment planning of electroporation-based medical interventions: electrochemotherapy, gene electrotransfer and irreversible electroporation. Phys Med Biol 2012; 57: 5425-40. 10.1088/0031-9155/57/17/5425ZupanicAKosBMiklavcicDTreatment planning of electroporation-based medical interventions: electrochemotherapy, gene electrotransfer and irreversible electroporationPhys Med Biol2012575425–4010.1088/0031-9155/57/17/5425Open DOISearch in Google Scholar

22 Cliniporator BC. Medical electroporation of tumors. In: Vernier PT, Rubinsky B, Juergen F. Miklavcic D, Rols MP, Raso J, et al, editors. Handbook of electroporation Springer International Publishing; 2017. p. 1-36. 10.1007/978-3-319-26779-1_214-1CliniporatorBCMedical electroporation of tumorsVernier PT, Rubinsky B, Juergen F. Miklavcic D, Rols MP, Raso J, et al, editors. Handbook of electroporationSpringer International Publishing20171–3610.1007/978-3-319-26779-1_214-1Open DOISearch in Google Scholar

23 Gehl J, Sersa G, Matthiessen LW, Muir T, Soden D, Occhini A, et al. Updated standard operating procedures for electrochemotherapy of cutaneous tumours and skin metastases. Acta Oncol 2018; 57: 874-82. 10.1080/0284186X.2018.1454602GehlJSersaGMatthiessenLWMuirTSodenDOcchiniAet alUpdated standard operating procedures for electrochemotherapy of cutaneous tumours and skin metastasesActa Oncol201857874–8210.1080/0284186X.2018.1454602Open DOISearch in Google Scholar

24 Edhemovic I, Gadzijev EM, Brecelj E, Miklavcic D, Kos B, Zupanic A, et al. Electrochemotherapy: a new technological approach in treatment of metastases in the liver. Technol Cancer Res Treat 2011; 10: 475-85. 10.1109/ TNB.2011.2128340EdhemovicIGadzijevEMBreceljEMiklavcicDKosBZupanicAet alElectrochemotherapy: a new technological approach in treatment of metastases in the liverTechnol Cancer Res Treat201110475–8510.1109/TNB.2011.2128340Open DOISearch in Google Scholar

25 Mali B, Gorjup V, Edhemovic I, Brecelj E, Cemazar M, Sersa G, et al. Electrochemotherapy of colorectal liver metastases - an observational study of its effects on the electrocardiogram. Biomed Eng Online 2015; 14 Suppl 3: S5. 10.1186/1475-925X-14-S3-S5MaliBGorjupVEdhemovicIBreceljECemazarMSersaGet alElectrochemotherapy of colorectal liver metastases - an observational study of its effects on the electrocardiogramBiomed Eng Online2015143S510.1186/1475-925X-14-S3-S5Open DOISearch in Google Scholar

26 De Buck S, Maes F, Ector J, Bogaert J, Dymarkowski S, Heidbüchel H, et al An augmented reality system for patient-specific guidance of cardiac catheter ablation procedures. IEEE Trans Med Imaging 2005; 24: 1512-4. 10.1109/TMI.2005.857661DeBuck SMaesFEctorJBogaertJDymarkowskiSHeidbüchelHet alAn augmented reality system for patient–specific guidance of cardiac catheter ablation proceduresIEEE Trans Med Imaging2005241512–410.1109/TMI.2005.857661Open DOISearch in Google Scholar

27 King AP, Rhode KS, Ma Y, Yao C, Jansen C, Razavi R, et al Registering pre-procedure volumetric images with intraprocedure 3-D ultrasound using an ultrasound imaging model. IEEE Trans Med Imaging 2010; 29: 924-37. 10.1109/TMI.2010.2040189KingAPRhodeKSMaYYaoCJansenCRazaviRet alRegistering pre-procedure volumetric images with intraprocedure 3-D ultrasound using an ultrasound imaging modelIEEE Trans Med Imaging201029924–3710.1109/TMI.2010.2040189Open DOISearch in Google Scholar

28 Zijdenbos AP, Dawant BM, Margolin RA, Palmer AC. Morphometric analysis of white matter lesions in MR images: method and validation. IEEE Trans Med Imaging 1994; 13: 716-24. 10.1109/42.363096ZijdenbosAPDawantBMMargolinRAPalmerACMorphometric analysis of white matter lesions in MR images: method and validationIEEE Trans Med Imaging199413716–2410.1109/42.363096Open DOISearch in Google Scholar

29 Saulis G, Lapė R, Pranevičiūtė R, Mickevičius D. Changes of the solution pH due to exposure by high-voltage electric pulses. Bioelectrochemistry 2005; 67: 101-8. 10.1016/j.bioelechem.2005.03.001SaulisGLapėRPranevičiūtėRMickevičiusDChanges of the solution pH due to exposure by high-voltage electric pulsesBioelectrochemistry200567101–810.1016/j.bioelechem.2005.03.001Open DOISearch in Google Scholar

30 Maglietti F, Michinski S, Olaiz N, Castro M, Suárez C, Marshall G. The role of Ph fronts in tissue electroporation based treatments. PLoS One 2013; 8: e80167. 10.1371/journal.pone.0080167MagliettiFMichinskiSOlaizNCastroMSuárezCMarshallGThe role of Ph fronts in tissue electroporation based treatmentsPLoS One20138e8016710.1371/journal.pone.0080167Open DOISearch in Google Scholar

31 Stehling MK, Guenther E, Mikus P, Klein N, Rubinsky L, Rubinsky B. Synergistic combination of electrolysis and electroporation for tissue ablation. PLoS One 2016; 11: e0148317. 10.1371/journal.pone.0148317StehlingMKGuentherEMikusPKleinNRubinskyLRubinskyBSynergistic combination of electrolysis and electroporation for tissue ablationPLoS One201611e014831710.1371/journal.pone.0148317Open DOISearch in Google Scholar

32 Rubinsky L, Guenther E, Mikus P, Stehling M, Rubinsky B. Electrolytic effects during tissue ablation by electroporation. Technol Cancer Res Treat 2016; 15: NP95-NP103. 10.1177/1533034615601549RubinskyLGuentherEMikusPStehlingMRubinskyBElectrolytic effects during tissue ablation by electroporationTechnol Cancer Res Treat201615NP95–NP10310.1177/1533034615601549Open DOISearch in Google Scholar

33 Orlowski S, Mir LM. Cell electropermeabilization: a new tool for biochemical and pharmacological studies. Biochim Biophys Acta 1993; 1154: 51-63.OrlowskiSMirLMCell electropermeabilization: a new tool for biochemical and pharmacological studiesBiochim Biophys Acta1993115451–6310.1016/0304-4157(93)90016-HSearch in Google Scholar

34 Jarm T, Cemazar M, Miklavcic D, Sersa G. Antivascular effects of electrochemotherapy: implications in treatment of bleeding metastases. Expert Rev Anticancer Ther 2010; 10: 729-46. 10.1586/era.10.43JarmTCemazarMMiklavcicDSersaGAntivascular effects of electrochemotherapy: implications in treatment of bleeding metastasesExpert Rev Anticancer Ther201010729–4610.1586/era.10.43Open DOISearch in Google Scholar

35 Groselj A, Kos B, Cemazar M, Urbancic J, Kragelj G, Bosnjak M, et al. Coupling treatment planning with navigation system: a new technological approach in treatment of head and neck tumors by electrochemotherapy. Biomed Eng Online 2015; 14 Suppl 3: S2. 10.1186/1475-925X-14-S3-S2GroseljAKosBCemazarMUrbancicJKrageljGBosnjakMet alCoupling treatment planning with navigation system: a new technological approach in treatment of head and neck tumors by electrochemotherapyBiomed Eng Online2015143S210.1186/1475-925X-14-S3-S2Open DOISearch in Google Scholar

36 Narayanan G, Hosein PJ, Beulaygue IC, Froud T, Scheffer HJ, Venkat SR, et al. Percutaneous image-guided irreversible electroporation for the treatment of unresectable, locally advanced pancreatic adenocarcinoma. J Vasc Interv Radiol 2017; 28: 342-48. 10.1016/j.jvir.2016.10.023NarayananGHoseinPJBeulaygueICFroudTSchefferHJVenkatSRet alPercutaneous image-guided irreversible electroporation for the treatment of unresectable, locally advanced pancreatic adenocarcinomaJ Vasc Interv Radiol201728342–4810.1016/j.jvir.2016.10.023Open DOISearch in Google Scholar

37 Beyer LP, Pregler B, Michalik K, Niessen C, Dollinger M, Müller M, et al. Evaluation of a robotic system for irreversible electroporation (IRE) of malignant liver tumors: initial results. Int J Comput Assist Radiol Surg 2017; 12: 803-9. 10.1007/s11548-016-1485-1BeyerLPPreglerBMichalikKNiessenCDollingerMMüllerMet alEvaluation of a robotic system for irreversible electroporation (IRE) of malignant liver tumors: initial resultsInt J Comput Assist Radiol Surg201712803–910.1007/s11548-016-1485-1Open DOISearch in Google Scholar

38 Markelc B, Sersa G, Cemazar M. Differential mechanisms associated with vascular disrupting action of electrochemotherapy: Intravital microscopy on the level of single normal and tumor blood vessels. PLoS One 2013; 8: e59557. 10.1371/journal.pone.0059557MarkelcBSersaGCemazarMDifferential mechanisms associated with vascular disrupting action of electrochemotherapy: Intravital microscopy on the level of single normal and tumor blood vesselsPLoS One20138e5955710.1371/journal.pone.0059557Open DOISearch in Google Scholar

39 Granata V, Fusco R, Setola SV, Piccirillo M, Leongito M, Palaia R, et al Early radiological assessment of locally advanced pancreatic cancer treated with electrochemotherapy. World J Gastroenterol 2017; 23: 4767-78 10.3748/wjg.v23.i26.4767GranataVFuscoRSetolaSVPiccirilloMLeongitoMPalaiaRet alEarly radiological assessment of locally advanced pancreatic cancer treated with electrochemotherapyWorld J Gastroenterol2017234767–7810.3748/wjg.v23.i26.4767Open DOISearch in Google Scholar

40 Appelbaum L, Ben-David E, Sosna J, Nissenbaum Y, Goldberg SN. US Findings after irreversible electroporation ablation: Radiologic-pathologic correlation. Radiology 2012; 262: 117-25. 10.1148/radiol.11110475AppelbaumLBen-DavidESosnaJNissenbaumYGoldbergSNUS Findings after irreversible electroporation ablation: Radiologic-pathologic correlationRadiology2012262117–2510.1148/radiol.11110475Open DOISearch in Google Scholar

41 Orlowski S, Belehradek J, Paoletti C, Mir LM. Transient electropermeabilization of cells in culture. Increase of the cytotoxicity of anticancer drugs. Biochem Pharmacol 1988; 37: 4727-33. 10.1016/0006-2952(88)903449OrlowskiSBelehradekJPaolettiCMirLMTransient electropermeabilization of cells in culture. Increase of the cytotoxicity of anticancer drugsBiochem Pharmacol1988374727–3310.1016/0006-2952(88)903449Open DOISearch in Google Scholar

42 Gasljevic G, Edhemovic I, Cemazar M, Brecelj E, Gadzijev EM, Music MM, et al. Histopathological findings in colorectal liver metastases after electrochemotherapy. PLoS One 2017; 12: e0180709. 10.1371/journal. pone.0180709GasljevicGEdhemovicICemazarMBreceljEGadzijevEMMusicMMet alHistopathological findings in colorectal liver metastases after electrochemotherapyPLoS One201712e018070910.1371/journal.pone.0180709Open DOISearch in Google Scholar