Open Access

Is postmastectomy radiotherapy really needed in breast cancer patients with many positive axillary lymph nodes?


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Danish Breast Cancer Cooperative Group, Nielsen HM, Overgaard M, Grau C, Jensen AR, Overgaard J. Study of failure pattern among high-risk breast cancer patients with or without postmastectomy radiotherapy in addition to adjuvant systemic therapy: long-term results from the Danish Breast Cancer Cooperative Group DBCG 82 b and c randomized studies. J Clin Oncol 2006; 24: 2268-75. 10.1200/JCO.2005.02.8738Danish Breast Cancer Cooperative GroupNielsenHMOvergaardMGrauCJensenAROvergaardJ.Study of failure pattern among high-risk breast cancer patients with or without postmastectomy radiotherapy in addition to adjuvant systemic therapy: long-term results from the Danish Breast Cancer Cooperative Group DBCG 82 b and c randomized studiesJ Clin Oncol20062422687510.1200/JCO.2005.02.8738Open DOISearch in Google Scholar

Clarke M, Collins R, Darby S, Davies C, Elphinstone P, Evans V, et al. Effects of radiotherapy and of differences in the extent of surgery for early breast cancer on local recurrence and 15-year survival: an overview of the randomised trials. Lancet 2005; 366: 2087-106. 10.1016/S0140-6736(05)67887-7ClarkeMCollinsRDarbySDaviesCElphinstonePEvansVEffects of radiotherapy and of differences in the extent of surgery for early breast cancer on local recurrence and 15-year survival: an overview of the randomised trialsLancet2005366208710610.1016/S0140-6736(05)67887-7Open DOISearch in Google Scholar

Ragaz J, Olivotto IA, Spinelli JJ, Phillips N, Jackson SM, Wilson KS, et al. Locoregional radiation therapy in patients with high-risk breast cancer receiving adjuvant chemotherapy: 20-year results of the British Columbia randomized trial. J Natl Cancer Inst 2005; 97: 116-26. 10.1093/jnci/djh297RagazJOlivottoIASpinelliJJPhillipsNJacksonSMWilsonKSLocoregional radiation therapy in patients with high-risk breast cancer receiving adjuvant chemotherapy: 20-year results of the British Columbia randomized trialJ Natl Cancer Inst2005971162610.1093/jnci/djh297Open DOISearch in Google Scholar

EBCTCG (Early Breast Cancer Trialists’ Collaborative Group). Effect of radiotherapy after mastectomy and axillary surgery on 10-year recurrence and 20-year breast cancer mortality: meta-analysis of individual patient data for 8135 women in 22 randomised trials. Lancet 2014; 383: 2127-35. 10.1016/S0140-6736(14)60488-8EBCTCG (Early Breast Cancer Trialists’ Collaborative Group)Effect of radiotherapy after mastectomy and axillary surgery on 10-year recurrence and 20-year breast cancer mortality: meta-analysis of individual patient data for 8135 women in 22 randomised trialsLancet201438321273510.1016/S0140-6736(14)60488-8Open DOISearch in Google Scholar

Coates AS, Winer EP, Goldhirsch A, Gelber RD, Gnant M, Piccart-Gebhart M, et al. Tailoring therapies - improving the management of early breast cancer: St Gallen International Expert Consensus on the Primary Therapy of Early Breast Cancer 2015. Ann Oncol 2015; 26: 1533-46. 10.1093/annonc/mdv221CoatesASWinerEPGoldhirschAGelberRDGnantMPiccart-GebhartMTailoring therapies - improving the management of early breast cancer: St Gallen International Expert Consensus on the Primary Therapy of Early Breast Cancer 2015Ann Oncol20152615334610.1093/annonc/mdv221Open DOISearch in Google Scholar

Darby SC, McGale P, Taylor CW, Peto R. Long-term mortality from heart disease and lung cancer after radiotherapy for early breast cancer: prospective cohort study of about 300,000 women in US SEER cancer registries. Lancet Oncol 2005; 6: 557-65. 10.1016/S1470-2045(05)70251-5DarbySCMcGalePTaylorCWPetoR.Long-term mortality from heart disease and lung cancer after radiotherapy for early breast cancer: prospective cohort study of about 300,000 women in US SEER cancer registriesLancet Oncol200565576510.1016/S1470-2045(05)70251-5Open DOISearch in Google Scholar

Darby SC, Ewertz M, McGale P, Bennet AM, Blom-Goldman U, Brønnum D, et al. Risk of ischemic heart disease in women after radiotherapy for breast cancer. N Engl J Med 2013; 368: 987-98. 10.1056/NEJMoa1209825DarbySCEwertzMMcGalePBennetAMBlom-GoldmanUBrønnumDRisk of ischemic heart disease in women after radiotherapy for breast cancerN Engl J Med20133689879810.1056/NEJMoa120982523484825Open DOISearch in Google Scholar

Marinko T, Borstnar S, Blagus R, Dolenc J, Bilban-Jakopin C. Early cardiotoxicity after adjuvant concomitant treatment with radiotherapy and trastuzumab in patients with breast cancer. Radiol Oncol 2018; 52: 204-212. 10.2478/raon-2018-0011MarinkoTBorstnarSBlagusRDolencJBilban-JakopinC.Early cardiotoxicity after adjuvant concomitant treatment with radiotherapy and trastuzumab in patients with breast cancerRadiol Oncol20185220421210.2478/raon-2018-0011604388730018525Open DOISearch in Google Scholar

Sardar P, Kundu A, Chatterjee S, Nohria A, Nairooz R, Bangalore S, et al. Long-term cardiovascular mortality after radiotherapy for breast cancer: a systematic review and meta-analysis. Clin Cardiol 2017; 40: 73-81. 10.1002/clc.22631SardarPKunduAChatterjeeSNohriaANairoozRBangaloreSLong-term cardiovascular mortality after radiotherapy for breast cancer: a systematic review and meta-analysisClin Cardiol201740738110.1002/clc.22631649053528244595Open DOISearch in Google Scholar

Union Against Cancer (UICC). TNM classification of malignant tumours. Sobin LH, Gospodarowicz MK, Wittekind C, editors. 7th edition. Chichester, UK: Wiley-Blackwell; 2009.Union Against Cancer (UICC)TNM classification of malignant tumoursSobinLHGospodarowiczMKWittekindC7thChichester, UKWiley-Blackwell2009Search in Google Scholar

Saez RA, McGuire WL, Clark GM. Prognostic factors in breast cancer. Semin Surg Oncol 1989; 5: 102-10.SaezRAMcGuireWLClarkGM.Prognostic factors in breast cancerSemin Surg Oncol198951021010.1002/ssu.29800502062657970Search in Google Scholar

Nemoto T, Natarajan N, Bedwani R, Vana J, Murphy GP Breast cancer in the medial half. Results of 1978 National Survey of the American College of Surgeons. Cancer 1983;51:1333-8. 10.1002/1097-0142(19830415)51:8<1333::AID-CNCR2820510802>3.0.CO;2-TNemotoTNatarajanNBedwaniRVanaJMurphyGPBreast cancer in the medial half. Results of 1978 National Survey of the American College of SurgeonsCancer1983511333810.1002/1097-0142(19830415)51:8<1333::AID-CNCR2820510802>3.0.CO;2-TOpen DOISearch in Google Scholar

Fisher B, Bauer M, Wickerham DL, Redmond CK, Fisher ER, Cruz AB, et al. Relation of number of positive axillary nodes to the prognosis of patients with primary breast cancer. An NSABP update. Cancer 1983; 52: 1551-7. 10.1002/1097-0142(19831101)52:9<1551::AID-CNCR2820520902>3.0.CO;2-3FisherBBauerMWickerhamDLRedmondCKFisherERCruzABRelation of number of positive axillary nodes to the prognosis of patients with primary breast cancer. An NSABP updateCancer1983521551710.1002/1097-0142(19831101)52:9<1551::AID-CNCR2820520902>3.0.CO;2-3Open DOISearch in Google Scholar

Early Breast Cancer Trialists’ Collaborative Group (EBCTCG). Effects of chemotherapy and hormonal therapy for early breast cancer on recurrence and 15-year survival: an overview of the randomised trials. Lancet 2005; 365: 1687-717. 10.1016/S0140-6736(05)66544-0Early Breast Cancer Trialists’ Collaborative Group (EBCTCG). Effects of chemotherapy and hormonal therapy for early breast cancer on recurrence and 15-year survival: an overview of the randomised trialsLancet2005365168771710.1016/S0140-6736(05)66544-0Open DOISearch in Google Scholar

Punglia RS, Morrow M, Winer EP, Harris JR. Local therapy and survival in breast cancer. N Engl J Med 2007; 356: 2399-405. 10.1056/NEJMra065241PungliaRSMorrowMWinerEPHarrisJR.Local therapy and survival in breast cancerN Engl J Med2007356239940510.1056/NEJMra065241Open DOISearch in Google Scholar

Halsted WS. I. The results of radical operations for the cure of carcinoma of the breast. Ann Surg 1907; 46: 1-19. 10.1097/SLA.0b013e31824b7e35HalstedWS. I.The results of radical operations for the cure of carcinoma of the breastAnn Surg19074611910.1097/SLA.0b013e31824b7e35Open DOISearch in Google Scholar

Fisher B, Gebhardt MC. The evolution of breast cancer surgery: past, present, and future. Semin Oncol 1978; 5: 385-94.FisherBGebhardtMC.The evolution of breast cancer surgery: past, present, and futureSemin Oncol1978538594Search in Google Scholar

Cianfrocca M, Goldstein LJ. Prognostic and predictive factors in early-stage breast cancer. Oncologist 2004; 9: 606-16. 10.1634/theoncologist.9-6-606CianfroccaMGoldsteinLJ.Prognostic and predictive factors in early-stage breast cancerOncologist200496061610.1634/theoncologist.9-6-606Open DOISearch in Google Scholar

Poortmans P. Postmastectomy radiation in breast cancer with one to three involved lymph nodes: ending the debate. Lancet 2014; 383: 2104-6. 10.1016/S0140-6736(14)60192-6PoortmansP.Postmastectomy radiation in breast cancer with one to three involved lymph nodes: ending the debateLancet20143832104610.1016/S0140-6736(14)60192-6Open DOISearch in Google Scholar

Haque R, Ahmed SA, Inzhakova G, Shi J, Avila C, Polikoff J, et al. Impact of breast cancer subtypes and treatment on survival: an analysis spanning two decades. Cancer Epidemiol Biomarkers Prev 2012; 21: 1848-55. 10.1158/1055-9965.EPI-12-0474HaqueRAhmedSAInzhakovaGShiJAvilaCPolikoffJImpact of breast cancer subtypes and treatment on survival: an analysis spanning two decadesCancer Epidemiol Biomarkers Prev20122118485510.1158/1055-9965.EPI-12-0474Open DOISearch in Google Scholar

Cameron D, Piccart-Gebhart MJ, Gelber RD, Procter M, Goldhirsch A, de Azambuja E, et al. 11 years’ follow-up of trastuzumab after adjuvant chemotherapy in HER2-positive early breast cancer: final analysis of the HERceptin Adjuvant (HERA) trial. Lancet 2017; 389: 1195-205. 10.1016/S0140-6736(16)32616-2CameronDPiccart-GebhartMJGelberRDProcterMGoldhirschAde AzambujaE11 years’ follow-up of trastuzumab after adjuvant chemotherapy in HER2-positive early breast cancer: final analysis of the HERceptin Adjuvant (HERA) trialLancet2017389119520510.1016/S0140-6736(16)32616-2Open DOISearch in Google Scholar

eISSN:
1581-3207
Language:
English
Publication timeframe:
4 times per year
Journal Subjects:
Medicine, Clinical Medicine, Radiology, Internal Medicine, Haematology, Oncology