<abstract xmlns="http://www.w3.org/1999/xhtml"> Background. Ultrasound is as a noninvasive method commonly used in the work-up of thyroid nodules. This study aimed to evaluate the usefulness of sonographic and elastosonographic parameters in the discrimination of malignancy. Patients and methods. 150 thyroid nodules were evaluated by gray-scale, Doppler and elastosonography. The cytological analysis revealed that 141 nodules were benign and 9 were malignant. Results. Orientation of the nodule was the only sonographic parameter associated with malignancy (p = 0.003). In the strain ratio analysis the best cut-off point was 1.935 to discriminate malignancy (p = 0.000), with 100% sensitivity, 76% specificity, 100% negative predictive value, 78.5% positive predictive value and 78% accuracy rate. There was a statistically significant correlation between the elasticity score and malignancy (p = 0.001). Most of the benign nodules had score 2 and 3, none of them displayed score 5. On the other hand, none of the malignant nodules had score 1 and 2, most of them displaying score 5. Conclusions. A change in the diagnostic algorithm of the thyroid nodules should be considered integrating the elastosonographic analysis</abstract>

Background. Ultrasound is as a noninvasive method commonly used in the work-up of thyroid nodules. This study aimed to evaluate the usefulness of sonographic and elastosonographic parameters in the discrimination of malignancy. Patients and methods. 150 thyroid nodules were evaluated by gray-scale, Doppler and elastosonography. The cytological analysis revealed that 141 nodules were benign and 9 were malignant. Results. Orientation of the nodule was the only sonographic parameter associated with malignancy (p = 0.003). In the strain ratio analysis the best cut-off point was 1.935 to discriminate malignancy (p = 0.000), with 100% sensitivity, 76% specificity, 100% negative predictive value, 78.5% positive predictive value and 78% accuracy rate. There was a statistically significant correlation between the elasticity score and malignancy (p = 0.001). Most of the benign nodules had score 2 and 3, none of them displayed score 5. On the other hand, none of the malignant nodules had score 1 and 2, most of them displaying score 5. Conclusions. A change in the diagnostic algorithm of the thyroid nodules should be considered integrating the elastosonographic analysis

The role of elastosonography, gray-scale and colour flow Doppler sonography in prediction of malignancy in thyroid nodules

Department of Radiology, Ankara Diskapı Training and Research Hospital, Ankara, Turkey

Department of General Surgery, Ankara Diskapi Training and Research Hospital, Ankara, Turkey

Department of Pathology, D. Abdurrahman Yurtaslan Ankara Oncology Training and Research Hospital, Ankara, Turkey

Ankara Research and Training Hospital, Department of Pathology, Ankara, Turkey

Radiology and Oncology

This work is licensed under the Creative Commons Attribution-NonCommercial-NoDerivatives 3.0 License.

Background. Ultrasound is as a noninvasive method commonly used in the work-up of thyroid nodules. This study aimed to evaluate the usefulness of sonographic...

The role of elastosonography, gray-scale and colour flow Doppler sonography in prediction of malignancy in thyroid nodules

Published Online: Nov 05, 2014

Page range: 348 - 353

Received: Nov 06, 2013

Accepted: Jan 27, 2014

DOI: https://doi.org/10.2478/raon-2014-0007

Keywords
ultrasound, Doppler, elastosonography, thyroid, malignancy

© by Idil Gunes Tatar

This work is licensed under the Creative Commons Attribution-NonCommercial-NoDerivatives 3.0 License.

The role of elastosonography, gray-scale and colour flow Doppler sonography in prediction of malignancy in thyroid nodules

Published Online: Nov 05, 2014

Page range: 348 - 353

Received: Nov 06, 2013

Accepted: Jan 27, 2014

DOI: https://doi.org/10.2478/raon-2014-0007

Keywordsultrasound, Doppler, elastosonography, thyroid, malignancy

© by Idil Gunes Tatar

This work is licensed under the Creative Commons Attribution-NonCommercial-NoDerivatives 3.0 License.

Keywords
ultrasound, Doppler, elastosonography, thyroid, malignancy