[
1. Podobnik J, Kocijancic I, Kovac V, Sersa I. 3T MRI in evaluation of asbestosrelated thoracic diseases - preliminary results. Radiol Oncol 2010 ; 44: 92-6.10.2478/v10019-010-0027-7342368522933897
]Search in Google Scholar
[
2. Mineo TC, Ambrogi V. Malignant pleural mesothelioma: factors influencing the prognosis. Oncology (Williston Park) 2012; 26: 1164-75.
]Search in Google Scholar
[
3. Kovac V, Zwitter M, Zagar T. Improved survival after introduction of chemotherapy for malignant pleural mesothelioma in Slovenia: Population-based survey of 444 patients. Radiol Oncol 2012; 46: 136-44.10.2478/v10019-012-0032-0347293823077450
]Search in Google Scholar
[
4. Lee CW, Murray N, Anderson H, Rao SC, Bishop W. Outcomes with firstline platinum-based combination chemotherapy for malignant pleural mesothelioma: a review of practice in British Columbia. Lung Cancer 2009; 64: 308-13.10.1016/j.lungcan.2008.09.00819004520
]Search in Google Scholar
[
5. Raeisi E, Aghamiri SMR, Bandi A, Rahmatpour N, Firoozabadi SM, Kafi-Abad SA, Mir LM. The antitumor efficiency of combined electrochemotherapy and single dose irradiation on a breast cancer tumor model. Radiol Oncol 2012; 46: 226-32.10.2478/v10019-012-0035-x347294723077461
]Search in Google Scholar
[
6. Jeromen A, Oblak I, Anderluh F, Velenik V, Vidmar MS, Ratoša I. Results of postoperative radiochemotherapy of the patients with resectable gastroesophageal junction adenocarcinoma in Slovenia. Radiol Oncol 2012; 46: 337-45.10.2478/v10019-012-0049-4357289023412351
]Search in Google Scholar
[
7. Vogelzang NJ, Rusthoven JJ, Symanowski J, Denham C, Kaukel E, Ruffie P, et al. Phase III study of pemetrexed in combination with cisplatin versus cisplatin alone in patients with malignant pleural mesothelioma. J Clin Oncol 2003; 21: 2636-44.10.1200/JCO.2003.11.13612860938
]Search in Google Scholar
[
8. Berk S, Dogan OT, Kilickap S, Epozturk K, Akkurt I, Seyfikli Z. Clinical characteristics, treatment and survival outcomes in malignant mesothelioma: eighteen years’ experience in Turkey. Asian Pac J Cancer Prev 2012; 13: 5735-9.10.7314/APJCP.2012.13.11.5735
]Search in Google Scholar
[
9. Helland A, Solberg S, Brustugun OT. Incidence and survival of malignant pleural mesothelioma in norway: a population-based study of 1686 cases. J Thorac Oncol 2012; 7: 1858-61.10.1097/JTO.0b013e318275b34623154557
]Search in Google Scholar
[
10. Kovac V, Zwitter M, Rajer M, Marin A, Debeljak A, Smrdel U, et al. A phase II trial of low-dose gemcitabine in a prolonged infusion and cisplatin for malignant pleural mesothelioma. Anticancer Drugs 2012; 23: 230-8.10.1097/CAD.0b013e32834d7a1c22027538
]Search in Google Scholar
[
11. Kao SC, Phan VH, Clarke SJ. Predictive markers for haematological toxicity of pemetrexed. Curr Drug Targets 2010; 11: 48-57.10.2174/13894501079003107219839928
]Search in Google Scholar
[
12. Berger SH, Pittman DL, Wyatt MD. Uracil in DNA: consequences for carcinogenesis and chemotherapy. Biochem Pharmacol 2008; 76: 697-706.10.1016/j.bcp.2008.05.019256202718599024
]Search in Google Scholar
[
13. Franke RM, Sparreboom A. Drug transporters: recent advances and therapeutic applications. Clin Pharmacol Ther 2010; 87: 3-7.10.1038/clpt.2009.23920019691
]Search in Google Scholar
[
14. Chattopadhyay S, Moran RG, Goldman ID. Pemetrexed: biochemical and cellular pharmacology, mechanisms, and clinical applications. Mol Cancer Ther 2007; 6: 404-17.10.1158/1535-7163.MCT-06-034317308042
]Search in Google Scholar
[
15. Silverton L, Dean M, Moitra K. Variation and evolution of the ABC transporter genes ABCB1, ABCC1, ABCG2, ABCG5 and ABCG8: implication for pharmacogenetics and disease. Drug Metabol Drug Interact 2011; 26: 169-79.10.1515/DMDI.2011.027737270922098604
]Search in Google Scholar
[
16. Adjei AA, Salavaggione OE, Mandrekar SJ, Dy GK, Ziegler KL, Endo C, et al. Correlation between polymorphisms of the reduced folate carrier gene (SLC19A1) and survival after pemetrexed-based therapy in non-small cell lung cancer: a North Central Cancer Treatment Group-based exploratory study. J Thorac Oncol 2010; 5: 1346-53.10.1097/JTO.0b013e3181ec18c4573541920651609
]Search in Google Scholar
[
17. Tiseo M, Giovannetti E, Tibaldi C, Camerini A, Di Costanzo F, Barbieri F, et al. Pharmacogenetic study of patients with advanced non-small cell lung cancer (NSCLC) treated with second-line pemetrexed or pemetrexedcarboplatin. Lung Cancer 2012; 78: 92-9.10.1016/j.lungcan.2012.07.00922889494
]Search in Google Scholar
[
18. Zucali PA, Giovannetti E, Destro A, Mencoboni M, Ceresoli GL, Gianoncelli L, et al. Thymidylate synthase and excision repair cross-complementing group-1 as predictors of responsiveness in mesothelioma patients treated with pemetrexed/carboplatin. Clin Cancer Res 2011; 17: 2581-90.10.1158/1078-0432.CCR-10-287321262916
]Search in Google Scholar
[
19. Kovac V, Zwitter M. Cisplatin with Alimta or gemcitabine in long infusion for mesothelioma (AGILI). Available at: http://clinicaltrials.gov/ct2/showNCT01281800. Accessed Januar y 16, 2013.
]Search in Google Scholar
[
20. Byrne MJ, Nowak AK. Modified RECIST criteria for assessment of response in malignant pleural mesothelioma. Ann Oncol 2004; 15: 257-60.10.1093/annonc/mdh05914760119
]Search in Google Scholar
[
21. National Cancer Institute Common Terminology Criteria for Adverse Events, version 4.0. Available at: http://ctep.cancer.gov/protocolDevelopment/electronic_applications/ctc.htm. Accessed February 15, 2012
]Search in Google Scholar
[
22. Erculj N, Kotnik BF, Debeljak M, Jazbec J, Dolzan V. The influence of folate pathway polymorphisms on high-dose methotrexate related toxicity and survival in children with non-Hodgkin malignant lymphoma. Radiol Oncol 2013; doi:10.2478/raon-2013-0076. 2013.10.26. [Epub ahea d of print]
]Search in Google Scholar
[
23. Erculj N, Kotnik BF, Debeljak M, Jazbec J, Dolzan V. Influence of folate pathway polymorphisms on high-dose methotrexate-related toxicity and survival in childhood acute lymphoblastic leukemia. Leuk Lymphoma 2012; 53: 1096-104.10.3109/10428194.2011.63988022074251
]Search in Google Scholar
[
24. Kastelic M, Koprivsek J, Plesnicar BK, Serretti A, Mandelli L, Locatelli I, et al. MDR1 gene polymorphisms and response to acute risperidone treatment. Prog Neuropsychopharmacol Biol Psychiatry 2010; 34: 387-92.10.1016/j.pnpbp.2010.01.00520060871
]Search in Google Scholar
[
25. Tregouet DA, Garelle V. A new JAVA interface implementation of THESIAS: testing haplotype effects in association studies. Bioinformatics 2007; 23: 1038-9.10.1093/bioinformatics/btm05817308338
]Search in Google Scholar
[
26. Erculj N, Kovac V, Hmeljak J, Franko A, Dodic-Fikfak M, Dolzan V. The influence of gemcitabine pathway polymorphisms on treatment outcome in patients with malignant mesothelioma. Pharmacogenet Genomics 2012; 22: 58-68.10.1097/FPC.0b013e32834e357222134350
]Search in Google Scholar
[
27. Righi L, Papotti MG, Ceppi P, Bille A, Bacillo E, Molinaro L, et al. Thymidylate synthase but not excision repair cross-complementation group 1 tumor expression predicts outcome in patients with malignant pleural mesothelioma treated with pemetrexed-based chemotherapy. J Clin Oncol 2010; 28: 1534-9.10.1200/JCO.2009.25.927520177021
]Search in Google Scholar
[
28. Christoph DC, Asuncion BR, Mascaux C, Tran C, Lu X, Wynes MW, et al. Folylpoly-glutamate synthetase expression is associated with tumor response and outcome from pemetrexed-based chemotherapy in malignant pleural mesothelioma. J Thorac Oncol 2012; 7: 1440-8.10.1097/JTO.0b013e318260deaa364594022895141
]Search in Google Scholar
[
29. Christoph DC, Asuncion BR, Hassan B, Tran C, Maltzman JD, O’Shannessy DJ, et al. Significance of folate receptor alpha and thymidylate synthase protein expression in patients with non-small-cell lung cancer treated with pemetrexed. J Thorac Oncol 2013; 8: 19-30.10.1097/JTO.0b013e31827628ff364593623242435
]Search in Google Scholar
[
30. Sun JM, Han J, Ahn JS, Park K, Ahn MJ. Significance of thymidylate synthase and thyroid transcription factor 1 expression in patients with nonsquamous non-small cell lung cancer treated with pemetrexed-based chemotherapy. J Thorac Oncol 2011; 6: 1392-9.10.1097/JTO.0b013e3182208ea821716147
]Search in Google Scholar
[
31. Smit EF, Burgers SA, Biesma B, Smit HJ, Eppinga P, Dingemans AM, et al. Randomized phase II and pharmacogenetic study of pemetrexed compared with pemetrexed plus carboplatin in pretreated patients with advanced non-small-cell lung cancer. J Clin Oncol 2009; 27: 2038-45.10.1200/JCO.2008.19.165019307503
]Search in Google Scholar
[
32. Hu Q, Li X, Su C, Chen X, Gao G, Zhang J, et al. Correlation between thymidylate synthase gene polymorphisms and efficacy of pemetrexed in advanced non-small cell lung cancer. Exp Ther Med 2012; 4: 1010-6.10.3892/etm.2012.730349412523226765
]Search in Google Scholar
[
33. Christensen KE, Rohlicek CV, Andelfinger GU, Michaud J, Bigras JL, Richter A, et al. The MTHFD1 p.Arg653Gln variant alters enzyme function and increases risk for congenital heart defects. Hum Mutat 2009; 30: 212-20.10.1002/humu.2083018767138
]Search in Google Scholar
[
34. Krajinovic M, Lemieux-Blanchard E, Chiasson S, Primeau M, Costea I, Moghrabi A. Role of polymorphisms in MTHFR and MTHFD1 genes in the outcome of childhood acute lymphoblastic leukemia. Pharmacogenomics J 2004; 4: 66-72.10.1038/sj.tpj.650022414647408
]Search in Google Scholar
[
35. Ranganathan P, Culverhouse R, Marsh S, Mody A, Scott-Horton TJ, Brasington R, et al. Methotrexate (MTX) pathway gene polymorphisms and their effects on MTX toxicity in Caucasian and African American patients with rheumatoid arthritis. J Rheumatol 2008; 35: 572-9.
]Search in Google Scholar
[
36. Sai K, Saito Y, Itoda M, Fukushima-Uesaka H, Nishimaki-Mogami T, Ozawa S, et al. Genetic variations and haplotypes of ABCC2 encoding MRP2 in a Japanese population. Drug Metab Pharmacokinet 2008; 23: 139-47.10.2133/dmpk.23.13918445995
]Search in Google Scholar
[
37. Sun N, Sun X, Chen B, Cheng H, Feng J, Cheng L, et al. MRP2 and GSTP1 polymorphisms and chemotherapy response in advanced non-small cell lung cancer. Cancer Chemother Pharmacol 2010; 65: 437-46.10.1007/s00280-009-1046-1279742119568750
]Search in Google Scholar
[
38. Campa D, Muller P, Edler L, Knoefel L, Barale R, Heussel CP, et al. A comprehensive study of polymorphisms in ABCB1, ABCC2 and ABCG2 and lung cancer chemotherapy response and prognosis. Int J Cancer 2012; 131: 2920-8.10.1002/ijc.2756722473764
]Search in Google Scholar
[
39. Niemi M, Pasanen MK, Neuvonen PJ. Organic anion transporting polypeptide 1B1: a genetically polymorphic transporter of major importance for hepatic drug uptake. Pharmacol Rev 2011; 63: 157-81.10.1124/pr.110.00285721245207
]Search in Google Scholar
[
40. Trevino LR, Shimasaki N, Yang W, Panetta JC, Cheng C, Pei D, et al. Germline genetic variation in an organic anion transporter polypeptide associated with methotrexate pharmacokinetics and clinical effects. J Clin Oncol 2009; 27: 5972-8.10.1200/JCO.2008.20.4156279304019901119
]Search in Google Scholar
[
41. Ramsey LB, Bruun GH, Yang W, Trevino LR, Vattathil S, Scheet P, et al. Rare versus common variants in pharmacogenetics: SLCO1B1 variation and methotrexate disposition. Genome Res 2012; 22: 1-8.10.1101/gr.129668.111324619622147369
]Search in Google Scholar
[
42. Vidan-Jeras B, Jurca B, Dolzan V, Jeras M, Breskvar K, Bohinjec M. Slovenian Caucasian normal. In: Gjertson D, Terasaki P, editors. HLA 1998. Kansas: American society for histocompatibility and immunogenetics, Lenexa; 1998 . p. 180-1.
]Search in Google Scholar
[
43. Erculj N, Kovac V, Hmeljak J, Dolzan V. The influence of platinum pathway polymorphisms on the outcome in patients with malignant mesothelioma. Ann Oncol 2012; 23: 961-7.10.1093/annonc/mdr32421765044
]Search in Google Scholar
[
44. Erculj N, Kovac V, Hmeljak J, Franko A, Dodic-Fikfak M, Dolzan V. DNA repair polymorphisms and treatment outcomes of patients with malignant mesothelioma treated with gemcitabine-platinum combination chemotherapy. J Thorac Oncol 2012; 7: 1609-17 10.1097/JTO.0b013e3182653d3122982660
]Search in Google Scholar