[1. Singer M, Deutschman C, Seymour C, et al. The third international consensus definitions for sepsis and septic shock (sepsis-3). JAMA 2016; 315: 801-10.10.1001/jama.2016.0287496857426903338]Search in Google Scholar
[2. Linde-Zwirble WT, Angus DC. Severe sepsis epidemiology: Sampling, selection, and society. Crit Care 2004; 8: 222-6.10.1186/cc291752285915312201]Search in Google Scholar
[3. Angus DC, Linde-Zwirble WT, Lidicker J, et al. Epidemiology of severe sepsis in the United States: analysis of incidence, outcome, and associated costs of care. Critical care medicine 2001; 29(7): 1303-1310.10.1097/00003246-200107000-0000211445675]Search in Google Scholar
[4. Henriksen DP, Laursen CB, Jensen TG, et al Incidence Rate of Community-Acquired Sepsis Among Hospitalized Acute Medical Patients – A Population-Based Survey. Crit Care Med 2015; 43: 13-21.10.1097/CCM.000000000000061125251760]Search in Google Scholar
[5. Mayr FB, Yende S, Angus DC. Epidemiology of severe sepsis. Virulence 2014; 5(1): 4–11.10.4161/viru.27372391638224335434]Search in Google Scholar
[6. Moerer O, Plock E, Mgbor U, et al. A German national prevalence study on the cost of intensive care: an evaluation from 51 intensive care units. Crit Care 2007; 11(3): R69.10.1186/cc5952220643517594475]Open DOISearch in Google Scholar
[7. Martin GS. Sepsis, severe sepsis and septic shock: changes in incidence, pathogens and outcomes. Expert Rev Anti-Infect Ther 2012; 10(6): 701-6.10.1586/eri.12.50348842322734959]Search in Google Scholar
[8. Ferrer R, Artigas A, Levy MM, et al. Improvement in process of care and outcome after a multicenter severe sepsis educational program in Spain. JAMA 2008; 299(19): 2294-303.10.1001/jama.299.19.229418492971]Search in Google Scholar
[9. Vincent JL, Rello J, Marshall J, et al. International study of the prevalence and outcomes in infection in intensive care units. JAMA 2009; 302: 2323-9.10.1001/jama.2009.175419952319]Search in Google Scholar
[10. Ranieri VM, Rubenfeld GD, Thompson BT, et al. ARDS Definition Task Force. Acute respiratory distress syndrome: the Berlin definition. JAMA 2012; 307: 2526–2533.10.1001/jama.2012.5669]Search in Google Scholar
[11. Vincent JL, Moreno R, Takala J, et al. The SOFA (Sepsis-related Organ Failure Assessment) score to describe organ dysfunction/failure. On behalf of the Working Group on Sepsis-Related Problems of the European Society of Intensive Care Medicine. Intensive Care Med 1996; 22(7): 707–10.10.1007/BF017097518844239]Search in Google Scholar
[12. Le Gall JR, Lemeshow S, Saulnier F. A new Simplified Acute Physiology Score (SAPS II) based on a European/North American multicenter study. JAMA 1993; 270: 2957–2963.10.1001/jama.1993.03510240069035]Search in Google Scholar
[13. Shankar-Hari M, Harrison DA, Rubenfeld GD, Rowan K. Epidemiology of sepsis and septic shock in critical care units: comparison between sepsis-2 and sepsis-3 populations using a national critical care database. Br J Anaesth 2017; 119(4): 626–636.10.1093/bja/aex23429121281]Search in Google Scholar
[14. Ogura H, Gando S, Saitoh D, et al. Epidemiology of severe sepsis in Japanese intensive care units: a prospective multicenter study. J Infect Chemother 2014; 20: 157–162.10.1016/j.jiac.2013.07.00624530102]Open DOISearch in Google Scholar
[15. Brun-Buisson C, Meshaka P, Pinton P, et al. EPISEPSIS: a reappraisal of the epidemiology and outcome of severe sepsis in French intensive care units. Intensive Care Med 2004; 30: 580–588.10.1007/s00134-003-2136-x]Search in Google Scholar
[16. Padkin A, Goldfrad C, Brady AR, et al. Epidemiology of severe sepsis occurring in the first 24 hrs in intensive care units in England, Wales, and Northern Ireland. Crit Care Med 2003; 31: 2332–2338.10.1097/01.CCM.0000085141.75513.2B14501964]Open DOISearch in Google Scholar
[17. J. Zhou, C. Qian, M. Zhao, et al. Epidemiology and outcome of severe sepsis and septic shock in intensive care units in mainland China. PLoS One 2014; 9(9); p. e107181.10.1371/journal.pone.0107181416733325226033]Search in Google Scholar
[18. Warmerdam M, Stolwijk F, Boogert A, et al. Initial disease severity and quality of care of emergency department sepsis patients who are older or younger than 70 years of age. PLoS One 2017; 12(9): e0185214.10.1371/journal.pone.0185214561264928945774]Search in Google Scholar
[19. Danai PA, Sinha S, Moss M, et al. Seasonal variation in the epidemiology of sepsis. Critical care medicine 2007; 35(2): 410–415.10.1097/01.CCM.0000253405.17038.4317167351]Open DOISearch in Google Scholar
[20. Mikkelsen ME, Shah CV, Meyer NJ, et al. The epidemiology of acute respiratory distress syndrome in patients presenting to the emergency department with severe sepsis. Shock Augusta Ga 2013; 40(5): 375–381.10.1097/SHK.0b013e3182a64682380049723903852]Open DOISearch in Google Scholar
[21. Kim W-Y, Hong S-B. Sepsis and Acute Respiratory Distress Syndrome: Recent Update. Tuberc Respir Dis (Seoul) 2016; 79(2): 53–7.10.4046/trd.2016.79.2.53482318427066082]Search in Google Scholar
[22. ARDSnet Investigators. Ventilation with lower tidal volumes as compared with traditional tidal volumes for acute lung injury and the acute respiratory distress syndrome. N Engl J Med 2000; 342: 1301–8.10.1056/NEJM20000504342180110793162]Search in Google Scholar
[23. Todi S, Chatterjee S, Bhattacharyya M. Epidemiology of severe sepsis in India. Crit Care 2007; 11(Suppl 2): 65.10.1186/cc5225]Search in Google Scholar
[24. Dabhi AS, Khedekar SS, Mehalingam V. A Prospective Study of Comparison of APACHE-IV & SAPS-II Scoring Systems and Calculation of Standardised Mortality Rate in Severe Sepsis and Septic Shock Patients. Journal of Clinical and Diagnostic Research : JCDR 2014;8(10):MC09-MC13.10.7860/JCDR/2014/9925.5052425320225478384]Search in Google Scholar
[25. Lee JH, Kim J, Kim K, et al. Albumin and C-reactive protein have prognostic significance in patients with community-acquired pneumonia. J Crit Care 2011; 26: 287-94.10.1016/j.jcrc.2010.10.00721129911]Open DOISearch in Google Scholar
[26. Artero A, Zaragoza R, Camarena JJ, et al. Prognostic factors of mortality in patients with community-acquired bloodstream infection with severe sepsis and septic shock. J Crit Care 2010; 25: 276-81.10.1016/j.jcrc.2009.12.00420149587]Open DOISearch in Google Scholar
[27. Seo MH, Choa M, You JS, et al. Hypoalbuminemia, Low Base Excess Values, and Tachypnea Predict 28-Day Mortality in Severe Sepsis and Septic Shock Patients in the Emergency Department. Yonsei Medical Journal 2016; 57(6): 1361-1369.10.3349/ymj.2016.57.6.1361501126727593863]Open DOISearch in Google Scholar
[28. Kojic D, Siegler BH, Uhle F, et al. Are there new approaches for diagnosis, therapy guidance and outcome prediction of sepsis? World J Exp Med 2015; 5(2): 50–63.10.5493/wjem.v5.i2.50]Search in Google Scholar
[29. Ogura H, Gando S, Saitoh D, et al. Epidemiology of severe sepsis in Japanese intensive care units: a prospective multicenter study. J Infect Chemother 2014; 20: 157–162.10.1016/j.jiac.2013.07.00624530102]Open DOISearch in Google Scholar
[30. Kempker JA, Martin GS. The changing epidemiology and definitions of sepsis. Clin Chest Med 2016; 37: 165–79.10.1016/j.ccm.2016.01.002488430627229635]Search in Google Scholar
[31. Bouza C, Lopez-Cuadrado T, Saz-Parkinson Z, et al. Epidemiology and recent trends of severe sepsis in Spain: a nationwide population-based analysis (2006–2011) BMC Infect Dis 2014; 14: 3863.10.1186/s12879-014-0717-7]Search in Google Scholar
[32. Baharoon S, Telmesani A, Tamim H, et al. Community-versus nosocomial-acquired severe sepsis and septic shock in patients admitted to a tertiary intensive care in Saudi Arabia, etiology and outcome. J Infect Public Health 2015; 8(5): 418-24.10.1016/j.jiph.2014.12.00325952595]Search in Google Scholar
[33. Seymour CW, Gesten F, Prescott HC, et al. Time to treatment and mortality during mandated emergency care for sepsis. N Engl J Med 2017; 376(23): 2235–2244.10.1056/NEJMoa1703058553825828528569]Search in Google Scholar
[34. Angus DC, van der Poll T: Severe sepsis and septic shock. N Engl J Med 2013; 369: 2063.10.1056/NEJMc1312359]Search in Google Scholar
[35. De Prost N, Razazi K, Brun-Buisson C. Unrevealing culture-negative severe sepsis. Critical Care. 2013; 17(5): 1001.10.1186/cc13022405635924074289]Open DOISearch in Google Scholar
[36. Grozdanovski K, Milenkovic Z, Demiri I, et al. Prediction of outcome from community-acquired severe sepsis and septic shock in tertiary-care university hospital in a developing country. Critical care research and practice 2012; 2012: 182324.10.1155/2012/182324348366523119151]Search in Google Scholar
[37. Fleischmann C, Thomas-Rueddel DO, et al. Hospital Incidence and Mortality Rates of Sepsis. Dtsch Arztebl Int 2016; 113(10): 159–66.]Search in Google Scholar
[38. Rhodes A, Evans LE, Alhazzani W, et al. Surviving Sepsis campaign: international guidelines for Management of Sepsis and Septic Shock: 2016. Intensive Care Med 2017; 43: 304–377.10.1007/s00134-017-4683-628101605]Search in Google Scholar
[39. Pro CI, Yealy DM, Kellum JA, et al. A randomized trial of protocol-based care for early septic shock. N Engl J Med 2014; 370(18): 1683–93.10.1056/NEJMoa1401602410170024635773]Search in Google Scholar
[40. The ARISE Investigators. the ANZICS Clinical Trial Group. Peake SL, Delaney A, Bailey M, et al. Goal-directed resuscitation for patients with early septic shock. N Engl J Med 2014; 371(16): 1496–1506.10.1056/NEJMoa140438025272316]Search in Google Scholar