<abstract xmlns="http://www.w3.org/1999/xhtml"><p>The novel coronavirus disease-2019 (COVID-19), caused by the severe acute respiratory syndrome-coronavirus-2 (SARS-CoV-2), has become a public health emergency of international concern. The first confirmed COVID-19 case in Indonesia was announced on 2 March 2020, and later on, 11,192 confirmed cases were reported as of 3 May. The World Health Organization has stated that performing a real-time reverse transcription–polymerase chain reaction (RT-PCR) specific for SARS-CoV-2 on specimens from the upper and the lower respiratory tracts, especially nasopharyngeal and oropharyngeal swabs, is the standard diagnostic procedure for COVID-19. In Indonesia, we also use other diagnostic tests, such as rapid antibody tests specific for SARS-CoV-2. Herein, we report an atypical case of COVID-19 and describe the diagnostic process, the clinical course, with progression to severe pneumonia on Week 3 of illness and the case management. We also try to highlight the possibility of false-negative RT-PCR tests.</p></abstract>

The novel coronavirus disease-2019 (COVID-19), caused by the severe acute respiratory syndrome-coronavirus-2 (SARS-CoV-2), has become a public health emergency of international concern. The first confirmed COVID-19 case in Indonesia was announced on 2 March 2020, and later on, 11,192 confirmed cases were reported as of 3 May. The World Health Organization has stated that performing a real-time reverse transcription–polymerase chain reaction (RT-PCR) specific for SARS-CoV-2 on specimens from the upper and the lower respiratory tracts, especially nasopharyngeal and oropharyngeal swabs, is the standard diagnostic procedure for COVID-19. In Indonesia, we also use other diagnostic tests, such as rapid antibody tests specific for SARS-CoV-2. Herein, we report an atypical case of COVID-19 and describe the diagnostic process, the clinical course, with progression to severe pneumonia on Week 3 of illness and the case management. We also try to highlight the possibility of false-negative RT-PCR tests.

An atypical case: RT-PCR-negative, sero-positive covid-19 patient

Department of General Medicine, St. Carolus Hospital

Department of Pulmonology, St. Carolus Hospital

Department of Pulmonology and Respiratory Medicine

Department of Clinical Pathology, St. Carolus Hospital

Department of Radiology, St. Carolus Hospital

Department of Internal Medicine, St. Carolus Hospital

Department of Anesthesiology and Intensive Care, St. Carolus Hospital

Pneumologia

This work is licensed under the Creative Commons Attribution-NonCommercial-NoDerivatives 4.0 International License.

Un caz atipic: pacient COVID 19 seropozitiv, RT-PCR negativ

The novel coronavirus disease-2019 (COVID-19), caused by the severe acute respiratory syndrome-coronavirus-2 (SARS-CoV-2), has become a public health emergency...

An atypical case: RT-PCR-negative, sero-positive covid-19 patient

Article Category: Clinical Cases

Published Online: Dec 31, 2020

Page range: 107 - 114

DOI: https://doi.org/10.2478/pneum-2020-0013

Keywords
COVID-19, SARS-CoV-2, RT-PCR, atypical case, sero-positive

© 2020 William Suriady et al., published by Sciendo

This work is licensed under the Creative Commons Attribution-NonCommercial-NoDerivatives 4.0 International License.

An atypical case: RT-PCR-negative, sero-positive covid-19 patient

Article Category: Clinical Cases

Published Online: Dec 31, 2020

Page range: 107 - 114

DOI: https://doi.org/10.2478/pneum-2020-0013

KeywordsCOVID-19, SARS-CoV-2, RT-PCR, atypical case, sero-positive

© 2020 William Suriady et al., published by Sciendo

This work is licensed under the Creative Commons Attribution-NonCommercial-NoDerivatives 4.0 International License.

Keywords
COVID-19, SARS-CoV-2, RT-PCR, atypical case, sero-positive