<abstract xmlns="http://www.w3.org/1999/xhtml"><p>A review on the radiobiological modeling of radiation-induced hypothyroidism after radiation therapy of head-and-neck cancers, breast cancer, and Hodgkin’s lymphoma is presented. The current review is based on data relating to dose-volume constrains and normal tissue complication probability (NTCP) as a function of either radiobiological or (pre)treatment-clinical parameters. Also, these data were explored in order to provide more helpful criteria for radiobiological optimization of treatment plans involving thyroid gland as a critical normal organ.</p></abstract>

A review on the radiobiological modeling of radiation-induced hypothyroidism after radiation therapy of head-and-neck cancers, breast cancer, and Hodgkin’s lymphoma is presented. The current review is based on data relating to dose-volume constrains and normal tissue complication probability (NTCP) as a function of either radiobiological or (pre)treatment-clinical parameters. Also, these data were explored in order to provide more helpful criteria for radiobiological optimization of treatment plans involving thyroid gland as a critical normal organ.

A review on the dosimetrical and radiobiological prediction of radiation-induced hypothyroidism in radiation therapy of head-and-neck cancer, breast cancer, and Hodgkin’s lymphoma survivors

Medical Physics Department, Medical School

Radiation Oncology Department, Imam Reza Hospital, Medical School

Oncology Institute, Department of Medical Physics

Molecular Medicine Research Center, Institute of Biomedicine

Polish Journal of Medical Physics and Engineering

This work is licensed under the Creative Commons Attribution-NonCommercial-NoDerivatives 4.0 License.

A review on the radiobiological modeling of radiation-induced hypothyroidism after radiation therapy of head-and-neck cancers, breast cancer, and Hodgkin’s...

A review on the dosimetrical and radiobiological prediction of radiation-induced hypothyroidism in radiation therapy of head-and-neck cancer, breast cancer, and Hodgkin’s lymphoma survivors

Published Online: Dec 24, 2018

Page range: 137 - 148

Received: May 12, 2018

Accepted: Sep 05, 2018

DOI: https://doi.org/10.2478/pjmpe-2018-0020

Keywords
radiation therapy, hypothyroidism, head-and-neck cancer, breast cancer, Hodgkin’s lymphoma, NTCP modelling, QUANTEC

© 2018 Aysan Mohammad Namdar et al., published by Sciendo

This work is licensed under the Creative Commons Attribution-NonCommercial-NoDerivatives 4.0 License.

A review on the dosimetrical and radiobiological prediction of radiation-induced hypothyroidism in radiation therapy of head-and-neck cancer, breast cancer, and Hodgkin’s lymphoma survivors

Published Online: Dec 24, 2018

Page range: 137 - 148

Received: May 12, 2018

Accepted: Sep 05, 2018

DOI: https://doi.org/10.2478/pjmpe-2018-0020

Keywordsradiation therapy, hypothyroidism, head-and-neck cancer, breast cancer, Hodgkin’s lymphoma, NTCP modelling, QUANTEC

© 2018 Aysan Mohammad Namdar et al., published by Sciendo

This work is licensed under the Creative Commons Attribution-NonCommercial-NoDerivatives 4.0 License.

Keywords
radiation therapy, hypothyroidism, head-and-neck cancer, breast cancer, Hodgkin’s lymphoma, NTCP modelling, QUANTEC