<abstract xmlns="http://www.w3.org/1999/xhtml"><p> The binary and ternary complex formations of poly(methyl vinyl ether-co-maleic anhydride) (PMVEMA) with copper ions and with bovine serum albumin (BSA) in the presence of copper ions in phosphate buffer solution at pH = 7 were examined by the techniques of UV-visible, fluorescence, dynamic light scattering, atomic force microscopy measurements. In the formation of binary complexes of PMVEMA-Cu(II), the addition of copper ions to the solution of PMVEMA in phosphate buffer solution at pH = 7 forms homogeneous solutions when the molar ratio of Cu(II)/MVEMA is 0.5. Then the formations of ternary complexes of PMVEMA-Cu(II)-BSA were examined. Study analysis revealed that the toxicities of polymer-metal and polymer-metal-protein mixture solutions depend on the nature and ratio of components in mixtures.</p></abstract>

The binary and ternary complex formations of poly(methyl vinyl ether-co-maleic anhydride) (PMVEMA) with copper ions and with bovine serum albumin (BSA) in the presence of copper ions in phosphate buffer solution at pH = 7 were examined by the techniques of UV-visible, fluorescence, dynamic light scattering, atomic force microscopy measurements. In the formation of binary complexes of PMVEMA-Cu(II), the addition of copper ions to the solution of PMVEMA in phosphate buffer solution at pH = 7 forms homogeneous solutions when the molar ratio of Cu(II)/MVEMA is 0.5. Then the formations of ternary complexes of PMVEMA-Cu(II)-BSA were examined. Study analysis revealed that the toxicities of polymer-metal and polymer-metal-protein mixture solutions depend on the nature and ratio of components in mixtures.

The Formation of Polycomplexes of Poly(Methyl Vinyl Ether-Co-Maleic Anhydride) and Bovine Serum Albumin in the Presence of Copper Ions

Üsküdar University, Faculty of Engineering and Natural Sciences, Department of Bioengineering, 34662 Uskudar-Istanbul, Turkey

Yildiz Technical University, Faculty of Chemical and Metallurgical Engineering, Department of Bioengineering, 34220 Esenler-Istanbul Turkey

Istanbul University, Faculty of Engineering, Department of Chemistry, 34320 Avcılar-Istanbul Turkey

Polish Journal of Chemical Technology

This work is licensed under the Creative Commons Attribution-NonCommercial-NoDerivatives 3.0 License.

The binary and ternary complex formations of poly(methyl vinyl ether-co-maleic anhydride) (PMVEMA) with copper ions and with bovine serum albumin (BSA) in the...

The Formation of Polycomplexes of Poly(Methyl Vinyl Ether-Co-Maleic Anhydride) and Bovine Serum Albumin in the Presence of Copper Ions

Published Online: Oct 03, 2014

Page range: 97 - 105

DOI: https://doi.org/10.2478/pjct-2014-0058

Keywords
polyelectrolyte, bovine serum albumin, copper ions, metal complexes, biological processes, biomaterials

© by Mesut Karahan

This work is licensed under the Creative Commons Attribution-NonCommercial-NoDerivatives 3.0 License.

The Formation of Polycomplexes of Poly(Methyl Vinyl Ether-Co-Maleic Anhydride) and Bovine Serum Albumin in the Presence of Copper Ions

Published Online: Oct 03, 2014

Page range: 97 - 105

DOI: https://doi.org/10.2478/pjct-2014-0058

Keywordspolyelectrolyte, bovine serum albumin, copper ions, metal complexes, biological processes, biomaterials

© by Mesut Karahan

This work is licensed under the Creative Commons Attribution-NonCommercial-NoDerivatives 3.0 License.

Keywords
polyelectrolyte, bovine serum albumin, copper ions, metal complexes, biological processes, biomaterials