[1. Chopra, I., Roberts, M. (2001). Tetracycline antibiotics: Mode of action, applications, molecular biology, and epidemiology of bacterial resistance. Microbiol Mol Biol Rev. 65 (2): 232-260. https://doi.org/10.1128/MMBR.65.2.232-260.2001 PMid:11381101 PMCid:PMC9902610.1128/MMBR.65.2.232-260.2001PMid:11381101PMCid:PMC99026]Open DOISearch in Google Scholar
[2. Valentín, S., Morales, A., Sánchez, J.L., Rivera, A. (2009). Safety and efficacy of doxycycline in the treatment of rosacea. Clin Cosmet Investig Dermatol. 2, 129-140. PMid:21436975 PMCid:PMC304792610.2147/CCID.S4296]Search in Google Scholar
[3. Agwuh, K. N., MacGowan, A. (2006). Pharmacokinetics and pharmacodynamics of the tetracyclines including glycylcyclines. J Antimicrob Chemother. 58, 256-265. https://doi.org/10.1093/jac/dkl224 PMid:1681639610.1093/jac/dkl224PMid:16816396]Open DOISearch in Google Scholar
[4. Redelsperger, I. M., Taldone T., Riedel, E. R., Lepherd, M. L., Lipman, N. S., Wolf, F. R. (2016). Stability of doxycycline in feed and water and minimal effective doses in tetracycline - inducible systems. J Am Assoc Lab Anim Sci. 55 (4): 467–474. PMid:27423155 PMCid:PMC4943619]Search in Google Scholar
[5. Ahmed, M. M., Rahman, M. M., Mahbub, K. R., Wahiduzzaman, M. (2011). Characterization of antibiotic resistant Salmonella spp. isolated from chicken eggs of Dhaka City. J Sci Res. 3 (1): 191-196. https://doi.org/10.3329/jsr.v3i1.610910.3329/jsr.v3i1.6109]Open DOISearch in Google Scholar
[6. Naz, S., Hanif, A., Maqbool, A., Ahmed, S., Muhammand, K. (2012). Isolation, characterization and monitoring of antibiotic resistance in Pasteurella multocida isolates from buffalo (Bubalus bubalis) herds around Lahore. J Anim Plant Sci. 22 (3): 242-245.]Search in Google Scholar
[7. Tejedor-Junco, M. T., González-Martín, M., Bermeo-Garrido, E., Villasana-Loaiza, R., Carretón-Gómez, E. (2018). Doxycycline treatment for Dirofilaria immitis in dogs: impact on Staphylococcus aureus and Enterococcus antimicrobial resistance. Vet Res Commun. 42 (3): 227–232. https://doi.org/10.1007/s11259-018-9727-z PMid:2993835310.1007/s11259-018-9727-zPMid:29938353]Open DOISearch in Google Scholar
[8. Maaland, M.G., Papich, M.G., Turnidge, J., Guardabassi, L. (2013). Pharmacodynamics of doxycycline and tetracycline against Staphylococcus pseudintermedius: proposal of canine-specific breakpoints for doxycycline. J Clin Microbiol. 51 (11): 3547-3554. https://doi.org/10.1128/JCM.01498-13 PMid:23966509 PMCid:PMC388973210.1128/JCM.01498-13]Search in Google Scholar
[9. Meijer, L. A., Ceyssens, K. G. F., de Greve, B. I. J. A. C., de Bruijn, W. (1993). Pharmacokinetics and bioavailability of doxycycline hyclate after oral administration in calves. Vet Q. 15, 1-5. https://doi.org/10.1080/01652176.1993.969435810.1080/01652176.1993.9694358]Open DOISearch in Google Scholar
[10. Laczay, P., Semjen, G., Lehel, J., Nagy, G. (2001). Pharmacokinetics and bioavailability of doxycycline in fasted and nonfasted broiler chickens. Acta Vet Hung. 49, 31-37. https://doi.org/10.1556/004.49.2001.1.5 PMid:1140268810.1556/004.49.2001.1.5]Search in Google Scholar
[11. Shabir, G. A. (2003). Validation of high-performance liquid chromatography methods for pharmaceutical analysis. Understanding the differences and similarities between validation requirements of the US Food and Drug Administration, the US Pharmacopeia and the International Conference on Harmonization. J Chromatogr A. 987, 57–66. https://doi.org/10.1016/S0021-9673(02)01536-410.1016/S0021-9673(02)01536-4]Open DOISearch in Google Scholar
[12. European Medicines Agency: [Internet]. Guideline on bioanalytical method validation. [cited 2011; last assessed on 09 November 2018]. https://www.ema.europa.eu/documents/scientific-guideline/guideline-bioanalytical-method-validation_en.pdf]Search in Google Scholar
[13. Fu, H., Zhang, L., Zhang, W. (2011). Preparation of doxycycline hyclate microcapsule and its pharmacokinetic in rabbit. Acta Vet et Zootechnica Sinica. 42 (10): 1438–1444.]Search in Google Scholar
[14. Castro, L. J., Sahagun, A. M., Diez, M. J., Fernandez, N., Sierra, M., Garcia, J. J. (2009). Pharmacokinetics of doxycycline in sheep after intravenous and oral administration. Vet J. 180, 389–395. https://doi.org/10.1016/j.tvjl.2008.02.001 PMid:1844084310.1016/j.tvjl.2008.02.001PMid:18440843]Open DOISearch in Google Scholar
[15. Zellner, M., Winkler, W., Hayden, H., Diestinger, M., Eliasen, M., Gesslbauer, B., et al. (2005). Quantitative validation of different protein precipitation methods in proteome analysis of blood platelets. Electrophoresis 26, 2481–2489. https://doi.org/10.1002/elps.200410262 PMid:1589546310.1002/elps.200410262PMid:15895463]Open DOISearch in Google Scholar
[16. Riond, J.L., Riviere, J.E. (1989). Doxycycline binding to plasma albumin of several species. J Vet Pharmacol Ther. 12 (3): 253-260. https://doi.org/10.1111/j.1365-2885.1989.tb00668.x PMid:281047410.1111/j.1365-2885.1989.tb00668.xPMid:2810474]Open DOISearch in Google Scholar
[17. Zeitlinger, M. A., Derendorf, H., Mouton, J. W., Cars, O., Craig, W. A., Andes, D., Theuretzbacher, U. (2011). Protein binding: do we ever learn? Antimicrob Agents Chemother. 55 (7) : 3067–3074. https://doi.org/10.1128/AAC.01433-10 PMid:21537013 PMCid:PMC312243110.1128/AAC.01433-10PMid:21537013PMCid:PMC3122431]Open DOISearch in Google Scholar
[18. Chaturvedi P., Esposito, C., Koroma, J., Cannon, E.P., Tanaka, S.K. (2003). In vitro assessment of plasma protein binding and metabolic stability of PTK 0796 (BAY 73-6944). Book of abstracts of the 43th Interscience conference of antimicrobial agents and chemotherapy. F-760, Chicago, USA.]Search in Google Scholar