Effects of vitamin C supplementation on the blood oxidative stress and antibody titre against Histophilus somni vaccination in calves
Published Online: Dec 29, 2020
Page range: 73 - 78
Received: Jul 06, 2020
Accepted: Dec 07, 2020
DOI: https://doi.org/10.2478/jvetres-2021-0002
Keywords
© 2021 K. Otomaru et al. published by Sciendo
This work is licensed under the Creative Commons Attribution-NonCommercial-NoDerivatives 3.0 License.
Introduction
The purpose of this study was to determine the effects of vitamin C supplementation on blood oxidative stress biomarkers and antibody response to vaccination in calves.
Material and methods
Thirty-four clinically healthy 2 week old Japanese Black calves were randomly assigned to two groups. Seventeen calves formed the VC group which received 1,000 mg of vitamin C daily from 2 to 8 weeks of age, and the other 17 calves of the control group did not receive supplementation. All calves received an inactivated
Results
The concentration of the serum reactive oxygen metabolites (d-ROMs), and the oxidative stress index (OSI), which is calculated from the d-ROMs and biological antioxidant potential, were significantly lower at 8 weeks of age in the VC group than in the control group (P < 0.05). The antibody titres to
Conclusion
Vitamin C supplementation to calves may reduce oxidative stress and enhance the antibody production after vaccination with