Cell viability in normal fibroblasts and liver cancer cells after treatment with iron (III), nickel (II), and their mixture

1. Ahamed M., Akhtar M.J., Siddiqui M.A., Ahmad J., Musarrat J., Al-Khedhairy A.A., AlSalhi M.S., Alrokayan S.A.: Oxidative stress mediated apoptosis induced by nickel ferrite nanoparticles in cultured A549 cells. Toxicology 2011, 283, 101–108.10.1016/j.tox.2011.02.010Search in Google Scholar

2. Alcântara D.D.F.A., Ribeiro H.F., Matos L.A., Sousa J.M.C., Burbano R.R., Bahia M.O.: Cellular responses induced in vitro by iron (Fe) in a central nervous system cell line (U343MGa). Genet Mol Res 2013, 12, 1554–1560.10.4238/2013.May.13.9Search in Google Scholar

3. Błasiak J., Arabski M., Petryński T., Małecka-Panas E., Woźniak K., Drzewoski J.: DNA damage in human colonic mucosa cells evoked by nickel and protective action of quercitin – involvement of free radicals? Cell Biol Toxicol 2002, 18, 279–288.10.1023/A:1016059112829Search in Google Scholar

4. Chen C.Y., Lin T.K., Chang Y.C., Wang Y.F., Shyu H.W., Lin K.H., Chou M.C.: Nickel(II)-induced oxidative stress, apoptosis, G2/M rest, and genotoxicity in normal rat kidney cells. J Toxicol Environ Health A 2010, 73, 529–539.10.1080/15287390903421250Search in Google Scholar

5. Chen C.Y., Wang Y.F., Lin Y.H., Yen S.F.: Nickel-induced oxidative stress and effect of antioxidants in human lymphocytes. Arch Toxicol 2003, 77, 123–130.10.1007/s00204-002-0427-6Search in Google Scholar

6. Eid R., Arab N.T.T., Greenwood M.T.: Iron mediated toxicity and programmed cell death: A review and a re-examination of existing paradigms. Biochim Biophys Acta 2017, 1864, 399–430.10.1016/j.bbamcr.2016.12.002Search in Google Scholar

7. Ermolli M., Menne C., Pozzi G., Serra M.A., Clerici L.A.: Nickel, cobalt, and chromium-induced cytotoxicity and intracellular accumulation in human hacat keratinocytes. Toxicology 2001, 159, 23–31.10.1016/S0300-483X(00)00373-5Search in Google Scholar

8. Fang J.L., Beland F.A.: Long-term exposure to zidovudine delays cell cycle progression, induces apoptosis, and decreases telomerase activity in human hepatocytes. Toxicol Sci 2009, 111, 120–130.10.1093/toxsci/kfp136273430919541796Search in Google Scholar

9. Fotakis G., Timbrell J.A.: In vitro cytotoxicity assays: comparison of LDH, neutral red, MTT, and protein assay in hepatoma cell lines following exposure to cadmium chloride. Toxicol Lett 2006, 160, 171–177.10.1016/j.toxlet.2005.07.00116111842Search in Google Scholar

10. Kalaivani P., Saranya S., Poornima P., Prabhakaran R., Dallemer F., Vijaya Padma V., Natarajan K.: Biological evaluation of new nickel(II) metallates: synthesis, DNA/protein binding, and mitochondrial mediated apoptosis in human lung cancer cells (A549) via ROS hypergeneration and depletion of cellular antioxidant pool. Eur J Med Chem 2014, 82, 584–599.10.1016/j.ejmech.2014.05.07524946146Search in Google Scholar

11. Kanaji A., Orhue V., Caicedo M.S., Virdi A.S., Sumner D.R., Hallab N.J., Yoshiaki T., Sena K.: Cytotoxic effects of cobalt and nickel ions on osteocytes in vitro. J Orthop Surg Res 2014, 9, 91.10.1186/s13018-014-0091-6419440725288055Search in Google Scholar

12. Klein C., Costa M.: Chapter 48–Nickel, In: Handbook on the Toxicology of Metals. edited by G.F. Nordberg and B.A. Fowler, Elsevier, 2015, pp. 1091–1089.10.1016/B978-0-444-59453-2.00048-2Search in Google Scholar

13. Kohgo Y., Ikuta K., Ohtake T., Torimoto Y., Kato J.: Body iron metabolism and pathophysiology of iron overload. Int J Hematol 2008, 88, 7–15.10.1007/s12185-008-0120-5251654818594779Search in Google Scholar

14. He W., Feng Y., Li X., Wei Y., Yang X.: Availability and toxicity of Fe(II) and Fe(III) in Caco-2 cells. J Zhejiang Univ Sci B 2008, 9, 707–712.10.1631/jzus.B0820023252888518763303Search in Google Scholar

15. Lee Y.J., Lim S.S., Baek B.J., An J.M., Nam H.S., Woo K.M., Cho M.K., Kim S.H., Lee S.H.: Nickel(II)-induced nasal epithelial toxicity and oxidative mitochondrial damage. Environ Toxicol Pharmacol 2016, 42, 76–84.10.1016/j.etap.2016.01.00526809061Search in Google Scholar

16. Lu H., Shi X., Costa M., Huang Ch.: Carcinogenic effect of nickel compounds. Mol Cell Biochem 2005, 279, 45–67.10.1007/s11010-005-8215-216283514Search in Google Scholar

17. Mazzotti F., Sabbioni E., Ponti J., Ghiani M., Fortaner S., Rossi G.L.: In vitro setting of dose-effect relationships of 32 metal compounds in the Balb/3T3 cell line, as a basis for predicting their carcinogenic potential. ATLA 2002, 30, 209–221.10.1177/02611929020300020711971756Search in Google Scholar

18. Meek B., Doull J.: Pragmatic challenges for the vision of toxicity testing in the 21^st century in a regulatory context: another Ames test? or a new edition of “the Red Book”?. Toxicol Sci 2009, 108, 19–21.10.1093/toxsci/kfp008264439919168570Search in Google Scholar

19. Minaeva O.V., Brodovskaya E.P., Pyataev M.A., Gerasimov M.V., Zharkov M.N., Yurlov I.A., Kulikov O.A., Kotlyarov A.A., Balykova L.A., Kokorev A.V., Zaborovskiy A.V., Pyataev N.A., Sukhorukov G.B.: Comparative study of cytotoxicity of ferromagnetic nanoparticles and magnetite containing polyelectrolyte microcapsules. J Phys: Conf Ser 2017, 784, 012038.Search in Google Scholar

20. Pandey M.R., Guo H.: Evaluation of cytotoxicity, genotoxicity, and embryotoxicity of insecticide propoxur using flounder gill (FG) cells and zebrafish embryos, Toxicol in Vitro 2014, 28, 340–35.10.1016/j.tiv.2013.11.01024291161Search in Google Scholar

21. Pilo F., Angelucci E.: A storm in the niche: iron, oxidative stress, and haemopoiesis. Blood Rev 2018, 32, 29–35.10.1016/j.blre.2017.08.00528847531Search in Google Scholar

22. Roe A.L., Snawder J.E., Benson R.W., Roberts D.W., Casciano D.A.: HepG2cells: an in vitro model for P450-dependent metabolism of acetaminophen. Biochem Biophys Res Commun 1993, 190, 15–19.10.1006/bbrc.1993.10038380689Search in Google Scholar

23. Schoonen W.G., de Roos J.A., Westerink W.M., Débiton E.: Cytotoxic effects of 110 reference compounds on HepG2 cells and for 60 compounds on HeLa, ECC-1 and CHO cells. II mechanistic assays on NAD(P)H, ATP and DNA contents. Toxicol in Vitro 2005, 19, 491–503.10.1016/j.tiv.2005.01.00215826807Search in Google Scholar

24. Terpilowska S., Siwicki A.K.: Interactions between chromium (III) and iron (III), molybdenum (III) or nickel (II): cytotoxicity, genotoxicity, and mutagenicity studies. Chemosphere 2018, 201, 780–789.10.1016/j.chemosphere.2018.03.06229550572Search in Google Scholar

25. Wang Y.F., Shyu H.W., Chang Y.C., Tseng W.C., Huang Y.L., Lin K.H., Chou M.C., Liu H.L., Chen C.Y.: Nickel (II)-induced cytotoxicity and apoptosis in human proximal tubule cells through a ROS- and mitochondria-mediated pathway. Toxicol Appl Pharmacol 2012, 259, 177–186.10.1016/j.taap.2011.12.02222245127Search in Google Scholar