<abstract xmlns="http://www.w3.org/1999/xhtml"><p>Chemical compounds containing the tropone structure (2,4,6-cycloheptatrien-1-one), in their molecule, called troponoids, characterized by a seven-membered ring, are distributed in some plants, bacteria and fungi, although they are relatively rare. ß-Thujaplicin (2-hydroxy-4-isopropyl-2,4,6-cycloheptatrien-1-one), also known as hinokitiol, is a natural compound found in several plants of the Cupressaceae family. Besides hinokitiol, related compounds were identified in Cupressaceae trees. It has been demonstrated that hinokitiol and its derivatives have various biological effects, such as antibacterial, antifungal, insecticidal, antimalarial, antitumor, anti-ischemic, iron chelating and the inhibitory activity against polyphenol oxidase activity. Activity similar to ß-thujaplicin has tropolone and its derivatives, which are not present nature. Due to the high scientific and practical interest, synthetic ß-thujaplicin and other troponoids have been produced for many years. In this review, the major biological effects of troponoids, mostly ß-thujaplicin and tropolone, on tyrosinase and polyphenol oxidase activity, ethylene production, antibacterial, antifungal and insecticidal activities, and biotransformation of ß-thujaplicin by cultured plant cells are presented. Accumulation of ß-thujaplicin and related troponoids has been shown in cell cultures of <italic>Cupressus lusitanica</italic> and other species of Cupressaceae. The biosynthetic pathway of the troponoids in plants, bacteria and fungi has been also briefly described.</p></abstract>

Chemical compounds containing the tropone structure (2,4,6-cycloheptatrien-1-one), in their molecule, called troponoids, characterized by a seven-membered ring, are distributed in some plants, bacteria and fungi, although they are relatively rare. ß-Thujaplicin (2-hydroxy-4-isopropyl-2,4,6-cycloheptatrien-1-one), also known as hinokitiol, is a natural compound found in several plants of the Cupressaceae family. Besides hinokitiol, related compounds were identified in Cupressaceae trees. It has been demonstrated that hinokitiol and its derivatives have various biological effects, such as antibacterial, antifungal, insecticidal, antimalarial, antitumor, anti-ischemic, iron chelating and the inhibitory activity against polyphenol oxidase activity. Activity similar to ß-thujaplicin has tropolone and its derivatives, which are not present nature. Due to the high scientific and practical interest, synthetic ß-thujaplicin and other troponoids have been produced for many years. In this review, the major biological effects of troponoids, mostly ß-thujaplicin and tropolone, on tyrosinase and polyphenol oxidase activity, ethylene production, antibacterial, antifungal and insecticidal activities, and biotransformation of ß-thujaplicin by cultured plant cells are presented. Accumulation of ß-thujaplicin and related troponoids has been shown in cell cultures of Cupressus lusitanica and other species of Cupressaceae. The biosynthetic pathway of the troponoids in plants, bacteria and fungi has been also briefly described.

The Biological Activities of Troponoids and Their Use in Agriculture A Review

Research Institute of Horticulture, Konstytucji 3 Maja 1/3, 96-100 Skierniewice, Poland

Siedlce University of Natural Sciences and Humanities Faculty of Natural Sciences, Department of Plant Physiology and Genetics Prusa 12, 08-110 Siedlce, Poland

School of Bioresources and Technology, King Mongkut’s University of Technology Thonburi, Thungkru, Bangkok 10140, Thailand

Journal of Horticultural Research

This work is licensed under the Creative Commons Attribution-NonCommercial-NoDerivatives 3.0 License.

{"article-title":"The Biological Activities of Troponoids and Their Use in Agriculture A Review"}

Chemical compounds containing the tropone structure (2,4,6-cycloheptatrien-1-one), in their molecule, called troponoids, characterized by a seven-membered...

The Biological Activities of Troponoids and Their Use in Agriculture A Review

Published Online: Sep 10, 2014

Page range: 5 - 19

Received: May 19, 2014

Accepted: Jun 11, 2014

DOI: https://doi.org/10.2478/johr-2014-0001

Keywords
Cupressaceae, ß-thujaplicin, tropolone, polyphenol oxidase, biosynthesis antibacterial, anti-fungal, insecticidal activity

© 2014 Marian Saniewski et. al.

This work is licensed under the Creative Commons Attribution-NonCommercial-NoDerivatives 3.0 License.

The Biological Activities of Troponoids and Their Use in Agriculture A Review

Published Online: Sep 10, 2014

Page range: 5 - 19

Received: May 19, 2014

Accepted: Jun 11, 2014

DOI: https://doi.org/10.2478/johr-2014-0001

KeywordsCupressaceae, ß-thujaplicin, tropolone, polyphenol oxidase, biosynthesis antibacterial, anti-fungal, insecticidal activity

© 2014 Marian Saniewski et. al.

This work is licensed under the Creative Commons Attribution-NonCommercial-NoDerivatives 3.0 License.

Keywords
Cupressaceae, ß-thujaplicin, tropolone, polyphenol oxidase, biosynthesis antibacterial, anti-fungal, insecticidal activity