Epicardial Adipose Tissue Role as a Marker of Higher Vulnerability in Patients with Coronary Artery Disease

1. Alexopoulus N, Raggi P. Epicardial Adipose Tissue: Another Tassel in the Complex Fabric of Atherosclerosis. Hematol Disord Drug Targets. 2018;18:17-26.10.2174/1871529X1766617012510355528124603Search in Google Scholar

2. Nakanishi K, Fukuda S, Tanaka A, et al. Epicardial Adipose Tissue Accumulation Is Associated With Renal Dysfunction and Coronary Plaque Morphology on Multidetector Computed Tomography. Circ J. 2015;80:196-201.10.1253/circj.CJ-15-047726497330Search in Google Scholar

3. Maurovich-Horvat P, Kallianos K, Engel LC, et al. Relationship of thoracic fat depots with coronary atherosclerosis and circulating inflammatory biomarkers. Obesity. 2015;23:1178-1184.10.1002/oby.21080444616025960369Search in Google Scholar

4. Doesch C, Jochims J, Streitner F, et al. Novel prognostic markers derived from cardiovascular magnetic resonance imaging in patients with stable chronic coronary artery disease. InVivo. 2015;29:737-747.Search in Google Scholar

5. Ridker PM. From C-reactive protein to interleukin-6 to Interleukin-1. Moving upstream to identify novel targets for atheroprotection. Circ Res. 2016;1:145-156.10.1161/CIRCRESAHA.115.306656479371126837745Search in Google Scholar

6. Hajsadeghi F, Nabavi V, Bhandari A, et al. Increased epicardial adipose tissue is associated with coronary artery disease and major adverse cardiovascular events. Atherosclerosis. 2014;237:486-489.10.1016/j.atherosclerosis.2014.09.03725463078Search in Google Scholar

7. Bo X, Ma L, Fan J, et al. Epicardial fat volume is correlated with coronary lesion and its severity. Int J Clin Exp Med. 2015;8:4328-4334.Search in Google Scholar

8. Romijn MA, Danad I, Bakkum MJ, et al. Incremental diagnostic value of epicardial adipose tissue for the detection of functionally relevant coronary artery disease. Atherosclerosis. 2015;242:161-166.10.1016/j.atherosclerosis.2015.07.00526188540Search in Google Scholar

9. Tanindi A, Erkan AF, Ekici B. Epicardial adipose tissue thickness can be used to predict major adverse cardiac events. Coron Artery Dis. 2015;26:686-691.10.1097/MCA.000000000000029626267746Search in Google Scholar

10. Mahabadi AA, Lehmann N, Kalsch H, et al. Association of epicardial adipose tissue with progression of coronary artery calcification is more pronounced in the early phase of atherosclerosis: Results from the Heinz Nixdorf Recall Study. JACC Cardiovasc Imaging. 2014;7:909-916.10.1016/j.jcmg.2014.07.00225190138Search in Google Scholar

11. Benedek T, Opincariu D, Rat N, Hodas R, Benedek I. The Assessment of Epicardial Adipose Tissue in Acute Coronary Syndrome Patients. A Systematic Review. Journal of Cardiovascular Emergencies. 2017;3:18-29.10.1515/jce-2017-0003Search in Google Scholar

12. Hodas R, Pop S, Opincariu D, et al. Correlations Between Severity of Coronary Lesions and Epicardial Fat Volume in Patients with Coronary Artery Disease – a Multislice CTbased Study. Journal of Interdisciplinary Medicine. 2016;1:71-78.10.1515/jim-2016-0014Search in Google Scholar

13. Iacobellis G, Corradi D, Sharma AM. Epicardial adipose tissue: anatomic, biomolecular and clinical relationship with the heart. Nat Clin Pract Cardiovasc Med. 2005;2:536-543.10.1038/ncpcardio031916186852Search in Google Scholar

14. Gitsioudis G, Schmahl C, Missiou A, et al. Epicardial adipose tissue is associated with plaque burden and composition and provides incremental value for the prediction of cardiac outcome. A clinical cardiac computed tomography angiography study. PLoS One. 2016;11:e0155120.10.1371/journal.pone.0155120487136627187590Search in Google Scholar

15. Nakanishi R, Rajani R, Cheng VY, et al. Increase in epicardial fat volume is associated with greater coronary artery calcification progression in subjects at intermediate risk by coronary calcium score: a serial study using non-contrast cardiac CT. Atherosclerosis. 2011;218:363-368.10.1016/j.atherosclerosis.2011.07.09321835407Search in Google Scholar

16. Bettencourt N, Toschke A, Leite D, et al. Epicardial adipose tissue is an independent predictor of coronary atherosclerotic burden. Int J Cardiol. 2012;158:26-32.10.1016/j.ijcard.2010.12.08521255849Search in Google Scholar

17. Mahabadi A, Berg M, Lehmann N, et al. Association of Epicardial Fat With Cardiovascular Risk Factors and Incident Myocardial Infarction in the General Population: The Heinz Nixdorf Recall Study. J Am Coll Cardiol. 2013;61:1388-1395.10.1016/j.jacc.2012.11.06223433560Search in Google Scholar

18. Nakanishi K, Fukuda S, Tanaka A, et al. Persistent epicardial adipose tissue accumulation is associated with coronary plaque vulnerability and future acute coronary syndrome in nonobese subjects with coronary artery disease. Atherosclerosis. 2014;237:353-360.10.1016/j.atherosclerosis.2014.09.01525310459Search in Google Scholar

19. Fukamachi D, Higuchi Y, Hiro T, et al. Association between the epicardial adipose tissue thickness and the presence of multivessel disease in patients with acute myocardial infarction. J Atheroscler Thromb. 2014;2:144-151.10.5551/jat.26120Search in Google Scholar

20. Wang T, Liu Q, Liu C, et al. Correlation of Echocardiographic Epicardial Fat Thickness with Severity of Coronary Artery Disease in Patients with Acute myocardial infarction. Echocardiography. 2014;31:1177-1181.10.1111/echo.1254524645963Search in Google Scholar

21. Tscharre M, Hauser C, Rohla M, et al. Epicardial adipose tissue and cardiovascular outcome in patients with acute coronary syndrome undergoing percutaneous coronary intervention. Eur Heart J Acute Cardiovasc Care. 2017;6:750-752.10.1177/204887261668060927864479Search in Google Scholar

22. Tanindi A, Kocaman S, Erkan A, et al. Epicardial adipose tissue thickness is associated with myocardial infarction and impaired coronary perfusion. Anatol J Cardiol. 2015;15:224-231.10.5152/akd.2014.5277533705924981296Search in Google Scholar

23. Opincariu D, Mester A, Dobra M, et al. Prognostic Value of Epicardial Fat Thickness as a Biomarker of Increased Inflammatory Status in Patients with Type 2 Diabetes Mellitus and Acute Myocardial Infarction. Journal of Cardiovascular Emergencies. 2016;2:11-18.10.1515/jce-2016-0003Search in Google Scholar

24. Tanindi A, Erkan A, Ekici B. Epicardial adipose tissue thickness can be used to predict major adverse cardiac events. Coron Artery Dis. 2015;26:686-691.10.1097/MCA.000000000000029626267746Search in Google Scholar

25. Husser O, Bodi V, Sanchis J, et al. White blood cell subtypes after STEMI: temporal evolution, association with cardiovascular magnetic resonance-derived infarct size and impact on the outcome. Inflammation. 2011;34:73-84.10.1007/s10753-010-9209-020419392Search in Google Scholar

26. Odeberg J, Freitag M, Forssell H, et al. Influence of pre-existing inflammation on the outcome of acute coronary syndrome: a cross-sectional study. BMJ Open. 2016;5:e009968.10.1136/bmjopen-2015-009968471624926758266Search in Google Scholar

27. Hajsadeghi F, Nabavi V, Bhandari, A et al. Increased epicardial adipose tissue is associated with coronary artery disease and major adverse cardiovascular events. Atherosclerosis. 2014;237:486-489.10.1016/j.atherosclerosis.2014.09.03725463078Search in Google Scholar