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Acute Eosinophilic Pneumonia Due to Vaping-Associated Lung Injury


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Fig. 1

Chest radiograph (CXR) demonstrating bilateral peripheral and central opacities with a basilar predominance
Chest radiograph (CXR) demonstrating bilateral peripheral and central opacities with a basilar predominance

Fig. 2

Chest computerized tomography (CT) demonstrating diffuse, broncho-centric bilateral ground glass opacities with coalescence to consolidation, largely in the lung bases
Chest computerized tomography (CT) demonstrating diffuse, broncho-centric bilateral ground glass opacities with coalescence to consolidation, largely in the lung bases

Fig. 3

Lung cytopathology, demonstrating rare foamy macrophages (black arrow).
Lung cytopathology, demonstrating rare foamy macrophages (black arrow).

Differential diagnosis considerations for acute eosinophilic pneumonia.

Differential diagnosis considerations
Eosinophilic granulomatosis with polyangiitis
Pulmonary fungal infections
Pulmonary parasitic infections
Medication effects
Pulmonary infiltration of eosinophils secondary to overwhelming peripheral eosinophilia

Diagnostic criteria for acute eosinophilic pneumonia.

Clinical diagnostic criteria for acute eosinophilic pneumonia
Febrile illness less than four weeks in duration
Hypoxemic respiratory failure
Diffuse pulmonary opacities on chest radiograph
Bronchoalveolar lavage (BAL) with cell count demonstrating >25% eosinophilia
Absence of other known causes for pulmonary eosinophilia

Characteristics of the clinical syndrome of vaping-associated lung injury.

Differential diagnosis considerations
Recent e-cigarette use
Pulmonary infiltrates on chest imaging
Absence of pulmonary infection
No evidence of an alternative cause
eISSN:
2393-1817
Language:
English