<abstract xmlns="http://www.w3.org/1999/xhtml"><sec id="j_jccm-2020-0005_s_007_w2aab2b8c35b1b7b1aab1c15b1Aa"><h3>Introduction</h3><p>The patient in critical condition, regardless of the cause of admission, continues to be a challenge for health systems due to the high mortality that it reports. There is a need to identify some marker of early obtaining, easy to interpret and with high relevance in the prognosis of these patients.</p></sec><sec id="j_jccm-2020-0005_s_008_w2aab2b8c35b1b7b1aab1c15b2Aa"><h3>Objective</h3><p>To determine the prognostic value of serum lactate in an Intensive Care Unit (ICU).</p></sec><sec id="j_jccm-2020-0005_s_009_w2aab2b8c35b1b7b1aab1c15b3Aa"><h3>Method</h3><p>One hundred and forty-five patients admitted to an ICU were enrolled in the study. The Acute Physiology and Chronic Health Evaluation II (APACHE) prognosis score, Sequential Organ Failure Assessment, hemodynamic support need, mechanical ventilation, cause of admission, stay in ICU, analytical and physiological variables were determined. The probability of survival of patients who had elevated and normal serum lactate levels was calculated. The risk of dying was determined using the Cox regression model.</p></sec><sec id="j_jccm-2020-0005_s_010_w2aab2b8c35b1b7b1aab1c15b4Aa"><h3>Results</h3><p>Twenty-eight patients died (19%) in the ICU. The serum lactate value was higher in the group of patients with trauma, infections, APACHE II and high creatinine levels; as well as with decreased mean arterial blood pressure, need for hemodynamic support and mechanical ventilation. The survival capacity was higher in patients who had normal serum lactate. Serum lactate was the sole independent predictor of mortality (AHR 1.28 [1.07-1.53], p = 0.008).</p></sec><sec id="j_jccm-2020-0005_s_011_w2aab2b8c35b1b7b1aab1c15b5Aa"><h3>Conclusions</h3><p>Patient assessment through the determination of serum lactate levels provides useful information in the initial evaluation of the critical patient.</p></sec></abstract>

IntroductionThe patient in critical condition, regardless of the cause of admission, continues to be a challenge for health systems due to the high mortality that it reports. There is a need to identify some marker of early obtaining, easy to interpret and with high relevance in the prognosis of these patients.ObjectiveTo determine the prognostic value of serum lactate in an Intensive Care Unit (ICU).MethodOne hundred and forty-five patients admitted to an ICU were enrolled in the study. The Acute Physiology and Chronic Health Evaluation II (APACHE) prognosis score, Sequential Organ Failure Assessment, hemodynamic support need, mechanical ventilation, cause of admission, stay in ICU, analytical and physiological variables were determined. The probability of survival of patients who had elevated and normal serum lactate levels was calculated. The risk of dying was determined using the Cox regression model.ResultsTwenty-eight patients died (19%) in the ICU. The serum lactate value was higher in the group of patients with trauma, infections, APACHE II and high creatinine levels; as well as with decreased mean arterial blood pressure, need for hemodynamic support and mechanical ventilation. The survival capacity was higher in patients who had normal serum lactate. Serum lactate was the sole independent predictor of mortality (AHR 1.28 [1.07-1.53], p = 0.008).ConclusionsPatient assessment through the determination of serum lactate levels provides useful information in the initial evaluation of the critical patient.

Prognostic Value of Serum Lactate Levels in Critically Ill Patients in an Intensive Care Unit

The Journal of Critical Care Medicine

This work is licensed under the Creative Commons Attribution-NonCommercial-NoDerivatives 4.0 License.

IntroductionThe patient in critical condition, regardless of the cause of admission, continues to be a challenge for health systems due to the high mortality...

Prognostic Value of Serum Lactate Levels in Critically Ill Patients in an Intensive Care Unit

Article Category: Research Article

Published Online: Jan 31, 2020

Page range: 59 - 64

Received: Nov 18, 2019

Accepted: Jan 29, 2020

DOI: https://doi.org/10.2478/jccm-2020-0005

Keywords
serum lactate, prognosis, intensive care unit, hyperlactatemia, APACHE

© 2020 Hedgar Berty Gutiérrez, Yenisey Arteaga Concepción, Jorge Soneira Pérez, Yanín Díaz Lara, Félix Mario Rivero López, Pedro Rosales Contreras, published by Sciendo

This work is licensed under the Creative Commons Attribution-NonCommercial-NoDerivatives 4.0 License.

Prognostic Value of Serum Lactate Levels in Critically Ill Patients in an Intensive Care Unit

Article Category: Research Article

Published Online: Jan 31, 2020

Page range: 59 - 64

Received: Nov 18, 2019

Accepted: Jan 29, 2020

DOI: https://doi.org/10.2478/jccm-2020-0005

Keywordsserum lactate, prognosis, intensive care unit, hyperlactatemia, APACHE

© 2020 Hedgar Berty Gutiérrez, Yenisey Arteaga Concepción, Jorge Soneira Pérez, Yanín Díaz Lara, Félix Mario Rivero López, Pedro Rosales Contreras, published by Sciendo

This work is licensed under the Creative Commons Attribution-NonCommercial-NoDerivatives 4.0 License.

Keywords
serum lactate, prognosis, intensive care unit, hyperlactatemia, APACHE