This work is licensed under the Creative Commons Attribution-NonCommercial-NoDerivatives 3.0 License.
Baumgartner, G. (1998). The impact of extracellular matrix on chemoresistance of solid tumors-experimental and clinical results of hyaluronidase as additive to cytostatic chemotherapy. Cancer Letters, 131(1), 85–99.BaumgartnerG.1998The impact of extracellular matrix on chemoresistance of solid tumors-experimental and clinical results of hyaluronidase as additive to cytostatic chemotherapy1311859910.1016/S0304-3835(98)00204-3Search in Google Scholar
Bordon, K. C., Wierel, G. A., Amorim, F. G., & Arantes, E. C. (2015). Arthropod venom hyaluronidases biochemical properties and potential applications in medicine and biotechnology. Journal of venomous Animals and Toxins including Tropical Diseases, 22, 21, 43. DOI:
10.1186/s40409-015-0042-7BordonK. C.WierelG. A.AmorimF. G.ArantesE. C.2015Arthropod venom hyaluronidases biochemical properties and potential applications in medicine and biotechnology22214310.1186/s40409-015-0042-7Open DOISearch in Google Scholar
Bradford, M. M. (1976). A rapid and sensitive method for the quantitation of microgram quantities of protein utilizing the principle of protein-dye binding. Analytical Biochemistry, 72, 248–254.BradfordM. M.1976A rapid and sensitive method for the quantitation of microgram quantities of protein utilizing the principle of protein-dye binding7224825410.1016/0003-2697(76)90527-3Search in Google Scholar
Farr, C., Menzel, J., Seeberger, J., & Schweigle, B. (1997). Clinical pharmacology and possible applications of hyaluronidase with reference to Hylase “Dessau”. Wiener Medizinische Wochenschrift, 147, 347–355.FarrC.MenzelJ.SeebergerJ.SchweigleB.1997Clinical pharmacology and possible applications of hyaluronidase with reference to Hylase “Dessau”147347355Search in Google Scholar
Girish, K. S., Mohankumari, H. P., Nagaraju, S., Vishwanath, B. S., Kemparaju, K. (2004). Hyaluronidase and protease activities from Indian snake venoms: neutralization by Mimosa pudica root extract. Fitoterapia, 75(3–4), 378–380. DOI:
10.1016/j.fitote.2004.01.006GirishK. S.MohankumariH. P.NagarajuS.VishwanathB. S.KemparajuK.2004Hyaluronidase and protease activities from Indian snake venoms: neutralization by Mimosa pudica root extract753–437838010.1016/j.fitote.2004.01.006Open DOISearch in Google Scholar
Gmachl, M. & Kreil, G. (1993). Bee venom hyaluronidase is homologous to a membrane protein of mammalian sperm. Proceedings of the National Academy of Sciences. USA, 90, 3569–3573.GmachlM.KreilG.1993Bee venom hyaluronidase is homologous to a membrane protein of mammalian sperm903569357310.1073/pnas.90.8.3569Search in Google Scholar
Guntenhöner, M. W., Pogrel, M. A., & Stem, R. (1992). A substrate-gel assay for hyaluronidase activity. Matrix, 12(5), 388–396. DOI:
10.1016/s0934-8832(11)80035-1GuntenhönerM. W.PogrelM. A.StemR.1992A substrate-gel assay for hyaluronidase activity12538839610.1016/s0934-8832(11)80035-1Open DOISearch in Google Scholar
Justo Jacomini, D. L., Campos Pereira, F. D., Aparecido dos Santos Pinto, J. R., dos Santos, L. D., da Silva Neto, A. J., Giratto, D.T., … Brochetto Braga, M. R. (2013). Hyaluronidase from the venom of the social wasp Polybia paulista (Hymenoptera, Vespidae): Cloning, structural modeling, purification, and immunological analysis. Toxicon, 15(64), 70–80. DOI:
10.1016/j.toxicon.2012.12.019Justo JacominiD. L.Campos PereiraF. D.Aparecido dos Santos PintoJ. R.dos SantosL. D.da Silva NetoA. J.GirattoD.T.Brochetto BragaM. R.2013Hyaluronidase from the venom of the social wasp Polybia paulista (Hymenoptera, Vespidae): Cloning, structural modeling, purification, and immunological analysis1564708010.1016/j.toxicon.2012.12.01923305623Open DOISearch in Google Scholar
Kemeny, D. M, Dalton, N., Lawrence, A. J., Pearce, F. L., Vernon, C. A. (1984). The purification and characterisation of hyaluronidase from the venom of the honey bee, Apis mellifera. European Journal of Biochemistry, 139(2), 217–23. DOI:
10.1111/j.1432-1033.1984.tb07997KemenyD. MDaltonN.LawrenceA. J.PearceF. L.VernonC. A.1984The purification and characterisation of hyaluronidase from the venom of the honey bee, Apis mellifera13922172310.1111/j.1432-1033.1984.tb07997Open DOISearch in Google Scholar
Kemparaju, K., & Girish, K. S. (2006). Snake venom hyaluronidase: a therapeutic target. Cell Biochemistry and Function, 24, 7–12. DOI:
10.1002/cbf.1261KemparajuK.GirishK. S.2006Snake venom hyaluronidase: a therapeutic target2471210.1002/cbf.126116245359Open DOISearch in Google Scholar
Klocker, J., Sabitzer, H., Raunik, W., Wieser, S., & Schumer, J. (1995). Combined application of cisplatin, vindesine, hyaluronidase and radiation for treatment of advanced squamous cell carcinoma of the head and neck. American Journal of Clinical Oncology, 18(5), 425–428. DOI:
10.1097/00000421-199510000-00013KlockerJ.SabitzerH.RaunikW.WieserS.SchumerJ.1995Combined application of cisplatin, vindesine, hyaluronidase and radiation for treatment of advanced squamous cell carcinoma of the head and neck18542542810.1097/00000421-199510000-000137572761Open DOISearch in Google Scholar
Kokot, Z. J., Matysiak, J., Kłos, J., Kędzia, B., & Hołderna-Kędzia, E. (2009). Application of Principal Component Analysis for evaluation of chemical and antimicrobial properties of honey bee (Apis mellifera) venom. Journal of Apicultural Research, 48(3), 168–175. DOI:
10.3896/IBRA.1.48.3.04KokotZ. J.MatysiakJ.KłosJ.KędziaB.Hołderna-KędziaE.2009Application of Principal Component Analysis for evaluation of chemical and antimicrobial properties of honey bee (Apis mellifera) venom48316817510.3896/IBRA.1.48.3.04Open DOISearch in Google Scholar
Kolarich, D., Leonard, R., Hemmer, W., & Altmann, F. (2005). The N-glycans of yellow jacket venom hyaluronidases and the protein sequence of its isoform in Vespula vulgaris. FEBS Journal, 272(20), 5182–5190. DOI:
10.1111/j.1742-4658.2005.04841.xKolarichD.LeonardR.HemmerW.AltmannF.2005The N-glycans of yellow jacket venom hyaluronidases and the protein sequence of its isoform in Vespula vulgaris272205182519010.1111/j.1742-4658.2005.04841.xOpen DOISearch in Google Scholar
Krylov, V. N. (1995): Bee venom. Properties, receipt, use: Novgorod, 224.KrylovV. N.1995receipt, use: Novgorod,224Search in Google Scholar
Laemmli, U. K. (1970). Cleavage of structural proteins during the assembly of the head of Bacteriophage T4. Nature, 227, 680–685.LaemmliU. K.1970Cleavage of structural proteins during the assembly of the head of Bacteriophage T422768068510.1038/227680a0Search in Google Scholar
Makris, G., Wright, J. D., Ingham, E. I., & Holland, K. T. (2004). The hyaluronate lyase of Staphylococcus aureus - a virulence factor? Microbiology, 150(6), 2005–2013. DOI:
10.1099/mic.0.26942-0MakrisG.WrightJ. D.InghamE. I.HollandK. T.2004The hyaluronate lyase of Staphylococcus aureus - a virulence factor?15062005201310.1099/mic.0.26942-0Open DOISearch in Google Scholar
Maksimenko, A. V., Petrova, M. L., Tischenko, E. G., & Schechilina, Y. V. (2001). Chemical modification of hyaluronidase regulates its inhibition by heparin. European Journal of Pharmaceutics and Biopharmaceutics, 51(1), 33–38. DOI:
10.1016/s0939-6411(00)00136-3MaksimenkoA. V.PetrovaM. L.TischenkoE. G.SchechilinaY. V.2001Chemical modification of hyaluronidase regulates its inhibition by heparin511333810.1016/s0939-6411(00)00136-3Open DOISearch in Google Scholar
Matsushita, O., & Okabe, A. (2001). Clostridial hydrolytic enzymes degrading extracellular components. Toxicon, 39(11), 1769–1780. DOI:
10.1016/s0041-0101(01)00163-5MatsushitaO.OkabeA.2001Clostridial hydrolytic enzymes degrading extracellular components39111769178010.1016/s0041-0101(01)00163-5Open DOISearch in Google Scholar
Moga, M. A, Dimienescu, O. G., Arvătescu, C. A., Ifteni, P., Pleş, L. (2018). Anticancer Activity of Toxins from Bee and Snake Venom- An Overview on Ovarian Cancer. Molecules, 23(3), 692–713. DOI:
10.3390/molecules23030692MogaM. ADimienescuO. G.ArvătescuC. A.IfteniP.PleşL.2018Anticancer Activity of Toxins from Bee and Snake Venom- An Overview on Ovarian Cancer23369271310.3390/molecules23030692601782129562696Open DOISearch in Google Scholar
Morey, S. S., Kiran, K. M., & Gadag, J. R. (2006). Purification and properties of hyaluronidase from Palamneus gravimanus (Indian black scorpion) venom, Toxicon, 47(2), 188–95. DOI:
10.1016/j.toxicon.2005.10.014MoreyS. S.KiranK. M.GadagJ. R.2006Purification and properties of hyaluronidase from Palamneus gravimanus (Indian black scorpion) venom4721889510.1016/j.toxicon.2005.10.01416359718Open DOISearch in Google Scholar
Muckenschnabel, I., Bernhardt, G., Spruss, T., & Buschauer, A. (1996). Hyaluronidase pretreatment produces selective melphalan enrichment in malignant melanoma in nude mice. Cancer Chemotherapy and Pharmacology, 38(1), 88–94. DOI:
10.1007/s002800050452MuckenschnabelI.BernhardtG.SprussT.BuschauerA.1996Hyaluronidase pretreatment produces selective melphalan enrichment in malignant melanoma in nude mice381889410.1007/s0028000504528603457Open DOISearch in Google Scholar
Nagaraju, S., Devaraja, S., & Kemparaju, K. (2007). Purification and properties of hyaluronidase from Hippasa partita (funnel web spider) venom gland extract. Toxicon, 50(3), 383–393. DOI:
10.1016/j.toxicon.2007.04.007NagarajuS.DevarajaS.KemparajuK.2007Purification and properties of hyaluronidase from Hippasa partita (funnel web spider) venom gland extract50338339310.1016/j.toxicon.2007.04.00717548101Open DOISearch in Google Scholar
O’Farrell, P. H. (1975). High resolution two-dimentional electrophoresis of proteins. Journal of Biological Chemistry, 25(10), 4007–4021.O’FarrellP. H.1975High resolution two-dimentional electrophoresis of proteins25104007402110.1016/S0021-9258(19)41496-8Search in Google Scholar
Pukrittayakamee, S., Warrel, D.A., Deasakorn, V., Mc Michael, A.J., White, N.J., Bunnag, G.D. (1988). The hyaluronidase activities of some Southeast Asian snake venoms. Toxicon, 26(7), 629–637. DOI:
10.1016/0041-0101(88)90245-0PukrittayakameeS.WarrelD.A.DeasakornV.McMichaelA.J.WhiteN.J.BunnagG.D.1988The hyaluronidase activities of some Southeast Asian snake venoms26762963710.1016/0041-0101(88)90245-0Open DOISearch in Google Scholar
Senff-Ribeiro, A., Henrique Da Silva, P., Chaim, O.M., Gremski, L.H., Paludo, K.S., Bertoni Da Silveira, R., … Veiga, S.S. (2008). Biotechnological applications of brown spider (Loxosceles genus) venom toxins. Biotechnology Advances, 26(3), 210–218. DOI:
10.1016/j.biotechadv.2007.12.003Senff-RibeiroA.Henrique Da SilvaP.ChaimO.M.GremskiL.H.PaludoK.S.Bertoni Da SilveiraR.VeigaS.S.2008Biotechnological applications of brown spider (Loxosceles genus) venom toxins26321021810.1016/j.biotechadv.2007.12.003Open DOISearch in Google Scholar
Smith, I. (1969). Acrylamide gel disc electrophoresis. In “Electrophoretic techniques” (Edited by Smith, I.) pp. 365–515, Academic press, New York.SmithI.1969In “Electrophoretic techniques” (Edited bySmithI.365515Academic pressNew York10.1016/B978-1-4831-9706-7.50015-4Search in Google Scholar
Sutti, R., Tamascia, M. L., Hyslop, S., & Rocha-E-Silva, T. A. (2014). Purification and characterization of a hyaluronidase from venom of the spider Vitalius dubius (Araneae, Theraphosidae). Journal of Venomous Animals and Toxins including Tropical Diseases, 20(2), 1–7. DOI:
10.1186/1678-9199-20-2SuttiR.TamasciaM. L.HyslopS.Rocha-E-SilvaT. A.2014Purification and characterization of a hyaluronidase from venom of the spider Vitalius dubius (Araneae, Theraphosidae)2021710.1186/1678-9199-20-2Open DOISearch in Google Scholar
Topchiyeva, A. & Mammadova F. Z. (2016). The seasonal activity of hyaluronidase in venom of a honey bee (Apis mellifera L. caucasica) in various regions of Azerbaijan. Journal of Entomology and Zoology Studies, 4(4), 1388–1391.TopchiyevaA.MammadovaF. Z.2016The seasonal activity of hyaluronidase in venom of a honey bee (Apis mellifera L. caucasica) in various regions of Azerbaijan4413881391Search in Google Scholar
Wahby, A. F., Mahdy, el-SM., El-Mezayen, H. A., Salama, W. H., Abdel-Aty, A. M., Fahmy, A. S. (2012). Egyptian horned viper Cerastes cerastes venom hyaluronidase: Purification, partial characterization and evidence for its action as a spreading factor. Toxicon, 60(8), 1380–1389. DOI:
10.1016/j.toxicon.2012.08.016WahbyA. F.Mahdyel-SM.El-MezayenH. A.SalamaW. H.Abdel-AtyA. M.FahmyA. S.2012Egyptian horned viper Cerastes cerastes venom hyaluronidase: Purification, partial characterization and evidence for its action as a spreading factor6081380138910.1016/j.toxicon.2012.08.016Open DOISearch in Google Scholar
Weber, K., & Osborn, M. (1969). The reliability of molecular weight determinations by dodecyl sulfate-polyacrylamide gel electrophoresis. Journal of Biological Chemistry, 244(16), 4406–4412.WeberK.OsbornM.1969The reliability of molecular weight determinations by dodecyl sulfate-polyacrylamide gel electrophoresis244164406441210.1016/S0021-9258(18)94333-4Search in Google Scholar
Wehbe, R., Frangieh, J., Rima, M., El Obeid, D., Sabatier, J., Fajloun, Z. (2019). Bee venom: overview of main compounds and bioactivities for therapeutic interests. Molecules, 24, 2997. DOI:
10.3390/molecules24162997WehbeR.FrangiehJ.RimaM.El ObeidD.SabatierJ.FajlounZ.2019Bee venom: overview of main compounds and bioactivities for therapeutic interests24299710.3390/molecules24162997672084031430861Open DOISearch in Google Scholar
Zahalka, M. A., Okon, E., Gosslar, U., Holzmann, B., Naor, D. (1995). Lymph node (but not spleen) invasion by murine lymphoma is both CD44- and hyaluronate-dependent. Journal of Immunology, 154(10), 5345–5355.ZahalkaM. A.OkonE.GosslarU.HolzmannB.NaorD.1995Lymph node (but not spleen) invasion by murine lymphoma is both CD44- and hyaluronate-dependent154105345535510.4049/jimmunol.154.10.5345Search in Google Scholar
Zheng, Y., Deng, X., Zhao, Y., & Martin-DeLeon, P.A. (2001). SPAM1 (PH-20) mutations and sperm dysfunction in mice with the Rb (6.16) or Rb (6.15) translocation. Mammalian Genome, 12(11), 822–829. DOI:
10.1007/s00335-001-1008-3ZhengY.DengX.ZhaoY.Martin-DeLeonP.A.2001SPAM1 (PH-20) mutations and sperm dysfunction in mice with the Rb (6.16) or Rb (6.15) translocation121182282910.1007/s00335-001-1008-311845284Open DOISearch in Google Scholar