<abstract xmlns="http://www.w3.org/1999/xhtml"><p>In our previous study, we demonstrated that the ethanol extracts of <italic>Artemisia dubia</italic> (<italic>A. dubia</italic>) and <italic>Aster scaber</italic> (<italic>A. scaber</italic>) have anti-nosemosis activity. In our present study, we intend to establish the anti-nosemosis activity of aqueous, ethyl acetate (EA), and butanol (BuOH) extracts of <italic>A. dubia</italic> and <italic>A. scaber</italic>. In order to determine the optimal dose, we performed both <italic>in vitro</italic> and <italic>in vivo</italic> toxicity for all the extracts and also carried out anti-nosemosis experiments. Although all of the extracts (aqueous, EA, and BuOH) showed <italic>in vitro</italic> and <italic>in vivo</italic> anti-nosemosis activity in a dose-dependent manner, the aqueous extracts of <italic>A. dubia</italic> and <italic>A. scaber</italic> showed more potent anti-nosemosis activity than the EA and BuOH extracts. Moreover, an aqueous extract of <italic>A. dubia</italic> + <italic>A. scaber</italic> demonstrated stronger anti-nosemosis activity compared with the aqueous extracts of either <italic>A. dubia</italic> or <italic>A. scaber</italic> alone. Although the main ingredients in <italic>A. dubia</italic> and <italic>A. scaber</italic> remain unclear, our results suggest that the active components of <italic>A. dubia</italic> and <italic>A. scaber</italic> could dissolve in the aqueous fraction.</p></abstract>

In our previous study, we demonstrated that the ethanol extracts of Artemisia dubia (A. dubia) and Aster scaber (A. scaber) have anti-nosemosis activity. In our present study, we intend to establish the anti-nosemosis activity of aqueous, ethyl acetate (EA), and butanol (BuOH) extracts of A. dubia and A. scaber. In order to determine the optimal dose, we performed both in vitro and in vivo toxicity for all the extracts and also carried out anti-nosemosis experiments. Although all of the extracts (aqueous, EA, and BuOH) showed in vitro and in vivo anti-nosemosis activity in a dose-dependent manner, the aqueous extracts of A. dubia and A. scaber showed more potent anti-nosemosis activity than the EA and BuOH extracts. Moreover, an aqueous extract of A. dubia + A. scaber demonstrated stronger anti-nosemosis activity compared with the aqueous extracts of either A. dubia or A. scaber alone. Although the main ingredients in A. dubia and A. scaber remain unclear, our results suggest that the active components of A. dubia and A. scaber could dissolve in the aqueous fraction.

Anti-Nosemosis Activity of <italic>Aster scaber</italic> and <italic>Artemisia dubia</italic> Aqueous Extracts

Department of Biology Education, College of Education

Journal of Apicultural Science

This work is licensed under the Creative Commons Attribution-NonCommercial-NoDerivatives 4.0 License.

Anti-Nosemosis Activity of  and  Aqueous Extracts

In our previous study, we demonstrated that the ethanol extracts of Artemisia dubia (A. dubia) and Aster scaber (A. scaber) have anti-nosemosis activity. In...

Anti-Nosemosis Activity of Aster scaber and Artemisia dubia Aqueous Extracts

Published Online: Jun 21, 2018

Page range: 27 - 38

Received: Jul 01, 2017

Accepted: Jan 08, 2018

DOI: https://doi.org/10.2478/jas-2018-0003

Keywords
nosemosis

© 2018 Jae Kwon Lee et al., published by Sciendo

This work is licensed under the Creative Commons Attribution-NonCommercial-NoDerivatives 4.0 License.

Anti-Nosemosis Activity of Aster scaber and Artemisia dubia Aqueous Extracts

Published Online: Jun 21, 2018

Page range: 27 - 38

Received: Jul 01, 2017

Accepted: Jan 08, 2018

DOI: https://doi.org/10.2478/jas-2018-0003

Keywordsnosemosis

© 2018 Jae Kwon Lee et al., published by Sciendo

This work is licensed under the Creative Commons Attribution-NonCommercial-NoDerivatives 4.0 License.

Keywords
nosemosis