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Novel pentacyclic triterpene isolated from seeds of Euryale Ferox Salisb. ameliorates diabetes in streptozotocin induced diabetic rats


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Ahmed D, Kumar V, Verma A, Gupta PS, Kumar V, Dhingra V, Mishra V, Sharma M. (2014). Antidiabetic, renal/hepatic/pancreas/cardiac protective and antioxidant potential of methanol/dichloromethane extract of Albizzia Leb-beck Benth. stem bark (ALEx) on streptozotocin induced diabetic rats. BMC Comp. and Alt. Medicine.14: 1–17.10.1186/1472-6882-14-243Search in Google Scholar

Ahmed D, Kumar V, Verma A, Shukla GS, Sharma M. (2015a). Antidiabetic, antioxidant, anti-hyperlipidemic effect of extract of Euryale ferox salisb. with enhanced histopathology of pancreas, liver and kidney in streptozotocin induced diabetic rats. Springer Plus.4: 1059–67.10.1186/s40064-015-1059-7448996726155454Search in Google Scholar

Ahmed D, Sharma M, Kumar V, Bajaj HK, Verma A. (2015b). 2β-hydroxybetulinic acid 3β-caprylate: an active principle from Euryale ferox salisb. seeds with antidiabetic, antioxidant, pancreas & hepatoprotective potential in streptozotocin induced diabetic rats. Journal of Food Science and Technology. 52: 5427–5441.10.1007/s13197-014-1676-0455464326344959Search in Google Scholar

Ahmed D, Khan MI, Kaithwas G, Roy S, Gautam S, Singh M, Devi U, Yadav, R, Rawat J, Saraf S. (2017). Molecular docking Analysis and Antidiabetic activity of Rifabutin against STZ-NA induced diabetes in albino wistar rats. Beni Suef Jour. of Basic and Applied Sci.6: 269–284.10.1016/j.bjbas.2017.04.010Search in Google Scholar

Arulselvan P, Subramanian SP. (2007). Beneficial effects of Murraya koenigii leaves on antioxidant defense system and ultrastructural changes of pancreatic cells in experimental diabetes in rats. Chem. Biol. Interact.165: 155–64.10.1016/j.cbi.2006.10.014Search in Google Scholar

Bolkent S, Yamardag R, Tabakogluoguz A, Ozsoyesacaon O. (2000). Effects of chord (Beta vulgaris L.Var.cicla) extract on pancreatic b-cells in Streotozotocin diabetic rats: a morphologic and biochemical study. J. Ethnopharmacol.73: 251–259.10.1016/S0378-8741(00)00328-7Search in Google Scholar

Erememisoglu A, Kelestimur F, Kokel AH, Utsun H, Tekol Y, Ustdal M. (1995). Hypoglycemic effect of Zizyphus jujube leaves. J. Pharm. Pharmacol.47: 72–74.10.1111/j.2042-7158.1995.tb05737.xSearch in Google Scholar

Evans JL, Goldfine ID, Maddux BA, Grodsky GM (2002). Oxidative stress and stress-activated signaling pathways: A unifying hypothesis of type 2 diabetes. Endocrine Reviews.23: 599–622.10.1210/er.2001-0039Search in Google Scholar

Gupta S, Sharma SB, Bansal SK, Prabhu KM. (2009). Antihyperglycemic and hypolipidemic activity of aqueous extract of Cassia auriculata L. leaves in experimental diabetes. J. Ethnopharm.123: 499–503.10.1016/j.jep.2009.02.019Search in Google Scholar

IDF Atlas 2015: International Diabetes Federation, 2015.Search in Google Scholar

Kaleem M, Asif M, Ahmed QU, Bano B. (2006). Antidiabetic and antioxidant activity of Annona squamosa extract in streptozotocin-induced diabetic rats. Singap. Med. J.47: 670–5.Search in Google Scholar

Keen H, Jarrett J. Complications of diabetes, 1982; London: Edward Arnold.Search in Google Scholar

King GL, McNeely MJ, Thorpe LE, Mau MLM, Ko J, Liu LL, Sun A, Hsu WC, Chow EA. (2012). Understanding and addressing unique needs of diabetes in Asian Americans native Hawaiians and Pacific islanders. Diabetes Care.35: 1181–1188.10.2337/dc12-0210Search in Google Scholar

Lee SE, Ju EM, Kim JH. (2002). Antioxidant activity of extracts from Euryale ferox seed. Exp Mol. Med.34: 100–106.10.1038/emm.2002.15Search in Google Scholar

Maritim AC, Sanders RA, Watkins JB. (2003). Diabetes, oxidative stress and antioxidants: a review. J. Biochem. Molec. Toxicol.17: 24–38.10.1002/jbt.10058Search in Google Scholar

Mithieux G. (2009). A novel function of intestinal gluconeogenesis: Central signalling in glucose and energy homeostasis. Nutrition.25: 881–884.10.1016/j.nut.2009.06.010Search in Google Scholar

Mitra SK, Goupmadhavan S, Muralidhar TS, Seshadri SJ. (1996). Effect of D-400, a herbomineral formulation on liver glycogen content and microscopic structure of pancreas and liver in streptozotocin-induced diabetes in rats. Indian J. Exp. Biol.34: 964–967.Search in Google Scholar

Nordlie RC, Foster JD, Lange AJ. (1999). Regulation of glucose production by the liver. Annu. Rev. Nutr.19: 379–406.10.1146/annurev.nutr.19.1.379Search in Google Scholar

Packer JE, Slater TF, Willson RL. (1978). Reactions of the carbon tetrachloride related peroxy free radical with amino acids: pulse radiolysis evidence. Life Sci.23: 2617–20.10.1016/0024-3205(78)90378-8Search in Google Scholar

Poretsky L. (ed.) Principles of Diabetes mellitus, Springer Science and Business Media 2010; 821–822.10.1007/978-0-387-09841-8Search in Google Scholar

Rai UN, Tripathi RD, Vajpayee P, Jha V, Ali MB. (2002). Bioaccumulation of toxic metals (Cr, Cd, Pb and Cu) by seeds of Euryale ferox salisb. (Makhana). Chemosphere.46: 267–272.10.1016/S0045-6535(01)00087-XSearch in Google Scholar

Rochette L, Zeller M, Cottin Y, Vergely C (2014). Diabetes, oxidative stress and therapeutic strategies. Biochimica et Biophysica Acta.1840: 2709–2729.10.1016/j.bbagen.2014.05.017Search in Google Scholar

Sun WK, Yuan H, Xu W, Qi L. (2011). Study on anti-oxidative activity of Euryale ferox salisb. shells extracts. Sci. Technol. Food Ind.4: 100–102.Search in Google Scholar

Suraamornkul S, Kwancharoen R, Ovartlarnporn M, Rawdaree P, Bajaj M. (2010). Insulin clamp-derived measurements of insulin sensitivity and insulin secretion in lean and obese Asian type 2 diabetic patients. Metabolic Syndrome and Related Disorder.8: 113–118.10.1089/met.2009.0030Search in Google Scholar

Szkudelski T. (2001). The mechanism of alloxan and streptozotocin action in β-cells of the rat pancreas. Physiol. Res.50: 536–546.Search in Google Scholar

Thannickal VJ, Fanburg BL. (2000). Reactive oxygen species in cell signalling. American Journal of Physiology - Lung Cellular and Molecular Physio.279: L1005–L1028.10.1152/ajplung.2000.279.6.L1005Search in Google Scholar

Wang L, Zhang XT, Zhang HY, Yao HY, Zhang H. (2010). Effect of Vaccinium bracteatum Thunb. leaves extract on blood glucose and plasma lipid levels in streptozotocin-induced diabetic mice. J. Ethnopharm.130: 465–9.10.1016/j.jep.2010.05.031Search in Google Scholar

Yoon KH, Ko SH, Cho JH, Lee JM, Ahn YB, Song KH, Yoo SJ, Kang MI. (2003). Selective beta-cell loss and alpha-cell expansion in patients with type 2 diabetes mellitus in Korea. The Journal of Clinical Endocrinology & Metabolism.88: 2300–2308.10.1210/jc.2002-020735Search in Google Scholar

Zhang XF, Tan BK. (2000). Anti-hyperglycemic and antioxidant properties of Andrographis paniculata in normal and diabetic rats. Clin. Exp. Pharmacol. Physiol.27: 358–63.10.1046/j.1440-1681.2000.03253.xSearch in Google Scholar

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Language:
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Journal Subjects:
Medicine, Clinical Medicine, Pharmacology, Toxicology