<abstract xmlns="http://www.w3.org/1999/xhtml"><p>Pesticides are the main remedy for pest eradication, but their use has been found to be harmful also to various non-target organisms. In this study, giant cell formation was observed in hepatocytes of experimental albino rats following two type II pyrethroid pesticdes, Cypermethrin and Beta-cyfluthrin. Histopathological examination was done for this purpose and the results revealed the formation of giant cells and polyploidy condition following intoxication of these experimental compounds with Beta-cyfluthrin, with an edge over, and Cypermethrin, probably due to structural differences.</p></abstract>

Pesticides are the main remedy for pest eradication, but their use has been found to be harmful also to various non-target organisms. In this study, giant cell formation was observed in hepatocytes of experimental albino rats following two type II pyrethroid pesticdes, Cypermethrin and Beta-cyfluthrin. Histopathological examination was done for this purpose and the results revealed the formation of giant cells and polyploidy condition following intoxication of these experimental compounds with Beta-cyfluthrin, with an edge over, and Cypermethrin, probably due to structural differences.

Multiple giant cell formation – A consequence of type II pyrethroid intoxication

Department of Zoology, School of Life Sciences

Interdisciplinary Toxicology

This work is licensed under the Creative Commons Attribution-NonCommercial-NoDerivatives 3.0 License.

Pesticides are the main remedy for pest eradication, but their use has been found to be harmful also to various non-target organisms. In this study, giant cell...

Multiple giant cell formation – A consequence of type II pyrethroid intoxication

Published Online: Mar 02, 2019

Page range: 178 - 179

Received: Nov 04, 2016

Accepted: Oct 03, 2017

DOI: https://doi.org/10.2478/intox-2018-0014

Keywords
pyrethroids, toxicity, liver

© 2018 Interdisciplinary Toxicology, published by Sciendo

This work is licensed under the Creative Commons Attribution-NonCommercial-NoDerivatives 3.0 License.

Multiple giant cell formation – A consequence of type II pyrethroid intoxication

Published Online: Mar 02, 2019

Page range: 178 - 179

Received: Nov 04, 2016

Accepted: Oct 03, 2017

DOI: https://doi.org/10.2478/intox-2018-0014

Keywordspyrethroids, toxicity, liver

© 2018 Interdisciplinary Toxicology, published by Sciendo

This work is licensed under the Creative Commons Attribution-NonCommercial-NoDerivatives 3.0 License.

Keywords
pyrethroids, toxicity, liver