Preoperative nutrition and postoperative liver function: a correlation study of pediatric living donor liver transplantation
, , , , , , and | Aug 14, 2018
About this article
Article Category: Original Article
Published Online: Aug 14, 2018
Page range: 157 - 164
Received: Sep 12, 2017
Accepted: Dec 18, 2017
DOI: https://doi.org/10.2478/fon-2018-0020
Keywords
© 2018 Ye-Feng Lu, Yan Wang, Ming-Zhu Huang, Xue-Fei Ren, Lei-Qing Gao, Dan Li, Yan-Fen Li, Yan Yang, published by Sciendo
This work is licensed under the Creative Commons Attribution-NonCommercial-NoDerivatives 3.0 License.
Correlation between weight Z value, Vitamin D level, and liver function.
| Items | TP | ALB | ALT | AST | AKP | GGT | DB | TB | Cr | Bile acid | Glu |
|---|---|---|---|---|---|---|---|---|---|---|---|
| Correlation | –0.062 | 0.054 | –0.349 | –0.288 | –0.171 | –0.281 | 0.189 | 0.196 | –0.121 | –0.011 | 0.345 |
| | 0.753 | 0.784 | 0.068 | 0.138 | 0.383 | 0.147 | 0.336 | 0.317 | 0.611 | 0.956 | 0.078 |
| Correlation | 0.201 | 0.120 | 0.197 | 0.458 | –0.049 | 0.034 | –0.115 | –0.036 | 0.318 | –0.203 | 0.029 |
| | 0.325 | 0.561 | 0.335 | 0.019* | 0.811 | 0.868 | 0.575 | 0.862 | 0.113 | 0.321 | 0.892 |
Demographic characteristics of recipients.
| Characteristics | Mean (SD) | Median (range) |
|---|---|---|
| Age (years) | 10.13 (9.53) | 7 (4–48) |
| Height (cm) | 69.07 (9.98) | 66 (58–100) |
| Weight (kg) | 8.09 (2.63) | 7.60 (4.90–16.50) |
| BMI (kg/m2) | 16.78 (2.67) | 16.20 (13.70–26.70) |
| Weight Z score | –0.89 (1.53) | –0.84 (–4.21 to 1.63) |
| Height Z score | –1.31 (1.49) | –1.11 (–4.57 to 1.48) |
| BMI Z score | –0.07 (1.68) | –0.61 (–2.49 to 5.20) |
| BMD | 0.12 (0.86) | 0.10 (–1.00 to 1.90) |
| Ca | 1.74 (0.14) | 1.71 (1.53–2.10) |
| Mg | 1.26 (0.09) | 1.26 (1.07–1.51) |
| Cu | 22.03 (2.15) | 22.86 (17.38–24.98) |
| Fe | 6.13 (0.96) | 6.09 (4.21–7.76) |
| Zn | 56.30 (9.79) | 57.90 (38.27–70.52) |
| Vitamin D | 8.09 (8.09) | 5.40 (1.93–36.42) |
| Vitamin D2 | 1.19 (0.63) | 1.06 (0.34–3.24) |
| Vitamin D3 | 6.92 (8.54) | 3.20 (1.01–35.80) |
| Vitamin D ratio | 0.42 (0.39) | 0.31 (0.02–1.62) |
Results of laboratory tests at Day 60 according to the gender, diagnosis, blood type, nutritional status, and GRWR status (mean±SD).
| Items | TP | ALB | ALT | AST | AKP | GGT | DB | TB | Cr | Bile acid | Glu |
|---|---|---|---|---|---|---|---|---|---|---|---|
| Male | 60.2±4.0 | 42.8±3.2 | 46.4±25.5 | 51.0±23.5 | 326.6±83.9 | 73.0±82.3 | 3.1±1.5 | 7.8±4.0 | 17.0±3.1 | 15.3±32.0 | 4.4±0.5 |
| Female | 60.2±3.8 | 42.8±3.2 | 53.6±39.7 | 51.4±20.3 | 329.4±138.5 | 92.2±166.9 | 3.2±1.6 | 7.9±3.9 | 16.4±3.0 | 7.5±6.3 | 4.4±0.5 |
| T statistics | 0.015 | 0.041 | –0.595 | –0.043 | –0.064 | –0.386 | –0.073 | –0.106 | 0.485 | 0.898 | 0.273 |
| | 0.989 | 0.968 | 0.557 | 0.966 | 0.949 | 0.703 | 0.942 | 0.917 | 0.631 | 0.377 | 0.787 |
| No | 60.3±3.6 | 42.9±3.0 | 60.5±41.0 | 52.1±19.5 | 342.1±139.5 | 99.4±181.9 | 3.6±1.8 | 9.1±4.7 | 17.1±3.1 | 19.5±35.9 | 4.3±0.5 |
| Yes | 60.1±4.1 | 42.8±3.4 | 43.3±25.6 | 50.6±23.3 | 318.9±94.5 | 71.7±85.4 | 2.8±1.3 | 7.0±3.1 | 16.4±3.0 | 6.1±3.2 | 4.4±0.5 |
| | 0.162 | 0.069 | 1.371 | 0.177 | 0.525 | 0.544 | 1.352 | 1.425 | 0.585 | 1.228 | –0.699 |
| | 0.872 | 0.945 | 0.182 | 0.861 | 0.604 | 0.591 | 0.188 | 0.166 | 0.564 | 0.247 | 0.491 |
| A | 59.8±3.0 | 42.6±2.8 | 47.7±24.2 | 45.8±12.6 | 274.5±58.3 | 68.1±30.2 | 2.9±0.8 | 6.9±2.9 | 16.6±3.7 | 5.4±1.5 | 4.0±0.3 |
| B | 60.4±4.0 | 43.4±2.4 | 49.0±25.4 | 50.6±13.9 | 313.3±48.8 | 45.5±23.7 | 3.6±2.2 | 9.6±5.2 | 16.7±2.8 | 24.4±41.4 | 4.6±0.6 |
| O | 60.5±4.4 | 42.5±4.0 | 53.6±42.0 | 55.0±28.6 | 364.2±150.1 | 116.8±180.4 | 3.0±1.4 | 7.2±3.3 | 16.9±3.0 | 6.6±5.5 | 4.4±0.4 |
| | 0.148 | 0.186 | 0.194 | 0.359 | 0.972 | 0.590 | 0.393 | 0.806 | 0.278 | 1.230 | 2.988 |
| | 0.930 | 0.905 | 0.899 | 0.783 | 0.422 | 0.627 | 0.759 | 0.503 | 0.841 | 0.321 | 0.052 |
| Abnormal | 59.3±2.8 | 42.0±1.9 | 71.3±50.4 | 66.7±31.5 | 357.8±158.7 | 148.7±244.1 | 2.3±1.2 | 5.8±2.9 | 15.0±3.2 | 9.9±5.7 | 4.1 ±0.2 |
| Normal | 60.4±4.1 | 43.0±3.5 | 44.3±25.0 | 47.0±16.5 | 319.9±99.6 | 64.5±76.1 | 3.4±1.5 | 8.4±3.9 | 17.1±2.8 | 11.8±25.9 | 4.5±0.5 |
| | –0.603 | –0.712 | 1.272 | 2.112 | 0.726 | 0.834 | –1.575 | –1.524 | –1.573 | –0.181 | –2.509 |
| | 0.552 | 0.483 | 0.253 | 0.044* | 0.474 | 0.441 | 0.127 | 0.139 | 0.128 | 0.858 | 0.019* |
| >1% | 60.6±3.8 | 43.0±3.5 | 42.6±24.6 | 45.8±16.7 | 321.9±106.9 | 57.4±75.1 | 3.1±1.1 | 7.7±3.0 | 17.1±2.8 | 5.3±2.9 | 4.3±0.5 |
| <1% | 59.4±3.9 | 42.4±2.6 | 63.7±42.3 | 60.9±26.4 | 339.0±126.8 | 127.9±190.1 | 3.2±2.1 | 8.2±5.2 | 15.9±3.3 | 22.4±36.9 | 4.5±0.5 |
| | –0.825 | –0.477 | 1.682 | 1.636 | 0.379 | 1.404 | 0.018 | 0.309 | –1.060 | 1.469 | 0.407 |
| | 0.417 | 0.637 | 0.105 | 0.126 | 0.708 | 0.172 | 0.986 | 0.760 | 0.299 | 0.176 | 0.425 |
Results of laboratory tests (mean±SD).
| Index | Day 1 | Day 2 | Day 3 | Day 4 | Day 5 | Day 6 | Day 7 | Day 14 | Day 30 | Day 60 |
|---|---|---|---|---|---|---|---|---|---|---|
| WBC | 9.7±4.7 | 9.8±3.5 | 7.8±2.6 | 6.0±2.3 | 8.2±4.1 | 14.2±8.8 | 13.9±7.6 | 9.6±3.5 | 8.6±3.1 | 8.3±2.6 |
| N% | 66.2±9.8 | 73.4±8.1 | 69.5±9.7 | 59.6±12.7 | 57.1±14.7 | 50.9±17.7 | 45.8±13.7 | 47.5±14.7 | 36.2±13.4 | 27.8±10.1 |
| HB | 93.8±11.7 | 96.8±12.3 | 95.9±12.5 | 97.2±12.4 | 98.8±12.9 | 99.0±13.7 | 96.1±16.6 | 94.0±9.5 | 102.7±14.1 | 113.6±14.4 |
| PLT | 163.2±114.5 | 163.9±93.6 | 171.3±102.1 | 160.6±79.1 | 153.3±77.4 | 141.5±54.5 | 147.4±54.2 | 293.6±125.2 | 324.3±108.5 | 231.0±66.3 |
| TP | 46.3±6.8 | 49.9±6.4 | 53.4±7.1 | 55.7±7.8 | 57.1±9.0 | 55.5±8.7 | 53.6±7.7 | 52.4±6.5 | 60.8±6.4 | 60.2±3.8 |
| ALB | 35.1±6.2 | 36.1±6.2 | 36.2±7.0 | 36.4±6.9 | 38.8±6.5 | 38.2±5.8 | 36.9±5.6 | 35.6±5.1 | 42.8±4.4 | 42.8±3.2 |
| ALT | 431.8±381.3 | 399.5±256.2 | 323.2±243.9 | 231.5±205.3 | 179.3±132.9 | 168.2±155.9 | 154.3±161.6 | 48.6±33.1 | 109.4±151.8 | 50.1±32.9 |
| AST | 449.0±337.1 | 283.4±165.7 | 163.3±118.7 | 97.2±62.9 | 90.6±40.3 | 115.6±151.3 | 99.4±112.7 | 43.9±24.9 | 76.3±83.9 | 51.2±21.5 |
| AKP | 179.9±110.5 | 153.6±85.2 | 162.1±111.5 | 145.0±99.5 | 130.5±73.5 | 131.5±76.4 | 127.8±70.8 | 176.0±107.8 | 331.6±170.1 | 328.0±112.4 |
| GGT | 85.1±64.3 | 71.9±80.0 | 82.8±97.1 | 95.5±101.2 | 96.5±80.1 | 97.2±81.8 | 87.4±79.3 | 90.9±154.6 | 132.4±246.5 | 82.6±129.5 |
| DB | 50.9±24.4 | 43.6±21.5 | 51.5±48.5 | 42.3±50.5 | 35.8±28.9 | 31.0±22.3 | 21.8±17.2 | 8.1±4.4 | 5.6±4.7 | 3.1±1.5 |
| TB | 102.2±70.2 | 82.4±80.3 | 74.6±59.5 | 60.3±54.1 | 49.0±32.7 | 39.0±25.7 | 29.1±20.4 | 12.8±6.2 | 10.0±6.4 | 7.8±3.9 |
| Cr | 15.3±6.3 | 13.6±3.6 | 15.1±5.2 | 16.7±5.3 | 16.4±4.9 | 16.1±4.1 | 15.7±4.0 | 15.5±4.0 | 15.1±3.1 | 16.7±3.0 |
| Bile acid | 3.9±4.9 | 9.1±17.0 | 14.0±14.8 | 21.3±33.0 | 15.4±15.1 | 17.2±22.4 | 10.6±8.7 | 9.3±19.0 | 7.7±7.4 | 11.4±23.0 |
| Glu | 6.4±2.4 | 8.3±2.8 | 6.9±1.6 | 6.4±1.1 | 6.0±1.6 | 6.2±3.8 | 5.8±6.1 | 4.1±2.6 | 4.1±0.7 | 4.4±0.5 |
| PT | 25.2±6.4 | 23.1±6.2 | 17.9±3.8 | 16.0±2.2 | 15.8±2.7 | 16.6±2.1 | 15.4±2.2 | 19.6±9.4 | 16.0±4.1 | 14.9±3.1 |
| INR | 2.25±0.6 | 2.1±0.6 | 1.6±0.3 | 1.4±0.2 | 1.4±0.3 | 1.5±0.2 | 1.4±0.2 | 1.8±0.8 | 1.4±0.4 | 1.3±0.3 |
| FK concentration | 6.9±3.4 | 8.1±3.9 | 10.1±3.3 | 9.8±3.1 | 8.8±3.4 | 8.3±2.5 | 7.0±2.4 | 7.2±4.0 | 7.4±1.9 |