Sex and salt intake dependent renin-angiotensin plasticity in the liver of the rat

Amara S, Alotaibi D, Tiriveedhi V. NFAT5/STAT3 interaction mediates synergism of high salt with IL-17 towards induction of VEGF-A expression in breast cancer cells. Oncol Lett 12, 933–943, 2016.10.3892/ol.2016.4713Search in Google Scholar

Bataller R, Gabele E, Parsons CJ, Morris T, Yang L, Schoonhoven R, Brenner DA, Rippe RA. Systemic infusion of angiotensin II exacerbates liver fibrosis in bile duct-ligated rats. Hepatology 41, 1046–1055, 2005.10.1002/hep.2066515841463Open DOISearch in Google Scholar

Bener A, Al-Suwaidi J, Al-Jaber K, Al-Marri S, Elbagi I E. Epidemiology of hypertension and its associated risk factors in the Qatari population. J Hum Hypertens 18, 529–530, 2004.10.1038/sj.jhh.1001691Open DOISearch in Google Scholar

Chen X, Cui Z, Zhang F, Chang W, Chen L, Liu L. Angiotensin II and cAMP regulate AT(1)-mRNA expression in rat cardiomyocytes by transcriptional mechanism. Eur J Pharmacol 448, 1–9, 2002.10.1016/S0014-2999(02)01900-312126964Open DOISearch in Google Scholar

Cholewa BC, Meister CJ, Mattson DL. Importance of the renin-angiotensin system in the regulation of arterial blood pressure in conscious mice and rats. Acta Physiol Scand 183, 309–320, 2005.10.1111/j.1365-201X.2004.01401.x15743391Search in Google Scholar

Dai YN, Wang JH, Zhu JZ, Lin JQ, Yu CH, Li YM. Angiotensin-converting enzyme inhibitors/angiotensin receptor blockers therapy and colorectal cancer: a systematic review and meta-analysis. Cancer Causes Control 26, 1245–1255, 2015.10.1007/s10552-015-0617-12608142626081426Open DOISearch in Google Scholar

Falconnet C, Bochud M, Bovet P, Maillard M, Burnier M. Gender difference in the response to an angiotensin-converting enzyme inhibitor and a diuretic in hypertensive patients of African descent. J Hypertens 22, 1213–1220, 2004.10.1097/00004872-200406000-0002315167457Open DOISearch in Google Scholar

Fan F, Tian C, Tao L, Wu H, Liu Z, Shen C, Jiang G, Lu Y. Candesartan attenuates angiogenesis in hepatocellular carcinoma via downregulating AT1R/VEGF pathway. Biomed Pharmacother 83, 704–711, 2016.10.1016/j.biopha.2016.07.03927470571Search in Google Scholar

Gunther S, Gimbrone MA Jr, Alexander RW. Regulation by angiotensin II of its receptors in resistance blood vessels. Nature 287, 230–232, 1980.10.1038/287230a06253796Search in Google Scholar

Harrison-Bernard LM, El-Dahr SS, O’Leary DF, Navar LG. Regulation of angiotensin II type 1 receptor mRNA and protein in angiotensin II-induced hypertension. Hypertension 33, 340–346, 1999.10.1161/01.HYP.33.1.3409931127Search in Google Scholar

Hayakawa Y, Aoyama T, Yokoyama C, Okamoto C, Komaki H, Minatoguchi S, Iwasa M, Yamada Y, Kawamura I, Kawasaki M, Nishigaki K, Mikami A, Suzuki F, Minatoguchi S. High salt intake damages the heart through activation of cardiac (pro) renin receptors even at an early stage of hypertension. PLoS One 10, e0120453, 2015.10.1371/journal.pone.0120453437056425799069Search in Google Scholar

He FJ, MacGregor GA. Salt, blood pressure and the renin-angiotensin system. J Renin Angiotensin Aldosterone Syst 4, 11–16, 2003.10.3317/jraas.2003.00112692748Search in Google Scholar

Herichova I, Soltesova D, Szantoova K, Mravec B, Neupauerova D, Vesela A, Zeman M. Effect of angiotensin II on rhythmic per2 expression in the suprachiasmatic nucleus and heart and daily rhythm of activity in Wistar rats. Regul Pept 186, 49–56, 2013.10.1016/j.regpep.2013.06.01623850797Search in Google Scholar

Hudson M, Rahme E, Behlouli H, Sheppard R, Pilote L. Sex differences in the effectiveness of angiotensin receptor blockers and angiotensin converting enzyme inhibitors in patients with congestive heart failure--a population study. Eur J Heart Fail 9, 602–609, 2007.10.1016/j.ejheart.2007.02.0011738393217383932Open DOISearch in Google Scholar

Igreja B, Pires NM, Wright LC, Soares-da-Silva P. Effects of zamicastat treatment in a genetic model of salt-sensitive hypertension and heart failure. Eur J Pharmacol 842, 125–132, 2019.10.1016/j.ejphar.2018.10.03030401628Search in Google Scholar

Imai N, Hashimoto T, Kihara M, Yoshida S, Kawana I, Yazawa T, Kitamura H, Umemura S. Roles for host and tumor angiotensin II type 1 receptor in tumor growth and tumor-associated angiogenesis. Lab Invest 87, 189–198, 2007.10.1038/labinvest.370050417318197Search in Google Scholar

Iwai M, Horiuchi M. Devil and angel in the renin-angiotensin system: ACE-angiotensin II-AT1 receptor axis vs. ACE2-angiotensin-(1-7)-Mas receptor axis. Hypertens Res 32, 533–536, 2009.10.1038/hr.2009.74709193119461648Search in Google Scholar

Kammerl MC, Richthammer W, Kurtz A, Kramer BK. Angiotensin II feedback is a regulator of renocortical renin, COX-2, and nNOS expression. Am J Physiol Regul Integr Comp Physiol 282, 1613–1617, 2002.10.1152/ajpregu.00464.200112010742Search in Google Scholar

Kobori H, Harrison-Bernard LM, Navar LG. Expression of angiotensinogen mRNA and protein in angiotensin II-dependent hypertension. J Am Soc Nephrol 12, 431–439, 2001.1118179010.1681/ASN.V123431257305011181790Search in Google Scholar

Koganti S, Snyder R, Thekkumkara T. Pharmacologic effects of 2-methoxyestradiol on angiotensin type 1 receptor down-regulation in rat liver epithelial and aortic smooth muscle cells. Gend Med 9, 76–93, 2012.10.1016/j.genm.2012.01.008332228922366193Search in Google Scholar

Koh SL, Ager EI, Christophi C. Liver regeneration and tumour stimulation: implications of the renin-angiotensin system. Liver Int 30, 1414–1426, 2010.10.1111/j.1478-3231.2010.02306.x20633100Open DOISearch in Google Scholar

Kostenis E, Milligan G, Christopoulos A, Sanchez-Ferrer CF, Heringer-Walther S, Sexton PM, Gembardt F, Kellett E, Martini L, Vanderheyden P, Schultheiss HP, Walther T. G-protein-coupled receptor Mas is a physiological antagonist of the angiotensin II type 1 receptor. Circulation 111, 1806–1813, 2005.10.1161/01.CIR.0000160867.23556.7D15809376Search in Google Scholar

Ljungman C, Kahan T, Schioler L, Hjerpe P, Hasselstrom J, Wettermark B, Bostrom KB, Manhem K. Gender differences in antihypertensive drug treatment: results from the Swedish Primary Care Cardiovascular Database (SPCCD). J Am Soc Hypertens 8, 882–890, 2014.10.1016/j.jash.2014.08.01525492831Search in Google Scholar

Lubel JS, Herath CB, Tchongue J, Grace J, Jia Z, Spencer K, Casley D, Crowley P, Sievert W, Burrell LM, Angus PW. Angiotensin-(1-7), an alternative metabolite of the renin-angiotensin system, is up-regulated in human liver disease and has antifibrotic activity in the bile-duct-ligated rat. Clin Sci (Lond) 117, 375–386, 2009.10.1042/CS2008064719371232Search in Google Scholar

Lyngso C, Erikstrup N, Hansen JL. Functional interactions between 7TM receptors in the renin-angiotensin system--dimerization or crosstalk? Mol Cell Endocrinol 302, 203–212, 2009.10.1016/j.mce.2008.09.01818930783Search in Google Scholar

Mao C, Liu R, Bo L, Chen N, Li S, Xia S, Chen J, Li D, Zhang L, Xu Z. High-salt diets during pregnancy affected fetal and offspring renal renin-angiotensin system. J Endocrinol 218, 61–73, 2013.10.1530/JOE-13-0139440609823620529Search in Google Scholar

Matsusaka T, Niimura F, Shimizu A, Pastan I, Saito A, Kobori H, Nishiyama A, Ichikawa I. Liver angiotensinogen is the primary source of renal angiotensin II. J Am Soc Nephrol 23, 1181–1189, 2012.10.1681/ASN.2011121159338065022518004Open DOISearch in Google Scholar

Mitra AK, Gao L, Zucker IH. Angiotensin II-induced upregulation of AT(1) receptor expression: sequential activation of NF-kappaB and Elk-1 in neurons. Am J Physiol Cell Physiol 299, 561–569, 2010.10.1152/ajpcell.00127.2010294431520554912Search in Google Scholar

Moreira de Macedo S, Guimaraes TA, Feltenberger JD, Sousa Santos SH. The role of renin-angiotensin system modulation on treatment and prevention of liver diseases. Peptides 62, 189–96, 2014.10.1016/j.peptides.2014.10.00525453980Search in Google Scholar

Mozaffarian D, Benjamin EJ, Go AS, Arnett DK, Blaha MJ, Cushman M, Das SR, de Ferranti S, Despres JP, Fullerton HJ, Howard VJ, Huffman MD, Isasi CR, Jimenez MC, Judd SE, Kissela BM, Lichtman JH, Lisabeth LD, Liu S, Mackey RH, Magid DJ, McGuire DK, Mohler ER 3rd, Moy CS, Muntner P, Mussolino ME, Nasir K, Neumar RW, Nichol G, Palaniappan L, Pandey DK, Reeves MJ, Rodriguez CJ, Rosamond W, Sorlie PD, Stein J, Towfighi A, Turan TN, Virani SS, Woo D, Yeh RW, Turner MB; American Heart Association Statistics Committee; Stroke Statistics Subcommittee. Heart Disease and Stroke Statistics-2016 Update: A Report From the American Heart Association. Circulation 133, e38–360, 2016.10.1161/CIR.000000000000036626811276Search in Google Scholar

Nehme A, Zibara K. Efficiency and specificity of RAAS inhibitors in cardiovascular diseases: how to achieve better end-organ protection? Hypertens Res 40, 903–909, 2017.2868016710.1038/hr.2017.6528680167Search in Google Scholar

Nelson C, Coady S (eds). The Jackson Heart Study Data Book A Report to the Cohort and Community. NHLBI Health Information Center, Bethesda, 2008.Search in Google Scholar

Ogihara T, Asano T, Ando K, Chiba Y, Sekine N, Sakoda H, Anai M, Onishi Y, Fujishiro M, Ono H, Shojima N, Inukai K, Fukushima Y, Kikuchi M, Fujita T. Insulin resistance with enhanced insulin signaling in high-salt diet-fed rats. Diabetes 50, 573–583, 2001.1124687710.2337/diabetes.50.3.57311246877Search in Google Scholar

Os I, Bratland B, Dahlof B, Gisholt K, Syvertsen JO, Tretli S. Female preponderance for lisinopril-induced cough in hypertension. Am J Hypertens 7, 1012–1015, 1994.784861510.1093/ajh/7.11.10127848615Search in Google Scholar

Ouali R, Berthelon MC, Begeot M, Saez JM. Angiotensin II receptor subtypes AT1 and AT2 are down-regulated by angiotensin II through AT1 receptor by different mechanisms. Endocrinology 138, 725–733, 1997.10.1210/endo.138.2.49529003008Search in Google Scholar

Rands VF, Seth DM, Kobori H, Prieto MC. Sexual dimorphism in urinary angiotensinogen excretion during chronic angiotensin II-salt hypertension. Gend Med 9, 207–218, 2012.10.1016/j.genm.2012.06.001341983722795463Search in Google Scholar

Reid IA. The renin angiotensin system: physiology, pathophysiology and pharmacology. Adv Physiol Educ 20, 237–245, 1998.10.1152/advances.1998.275.6.S236Search in Google Scholar

Rogers JL, Mitchell AR, Maric C, Sandberg K, Myers A, Mulroney SE. Effect of sex hormones on renal estrogen and angiotensin type 1 receptors in female and male rats. Am J Physiol Regul Integr Comp Physiol 292, 794–799, 2007.10.1152/ajpregu.00424.200616990489Search in Google Scholar

Sandberg K, Ji H. Sex differences in primary hypertension. Biol Sex Differ 3,7, 2012.10.1186/2042-6410-3-7333182922417477Search in Google Scholar

Santos RA, Simoes E Silva AC, Maric C, Silva DM, Machado RP, de Buhr I, Heringer-Walther S, Pinheiro SV, Lopes MT, Bader M, Mendes EP, Lemos VS, Campagnole-Santos MJ, Schultheiss HP, Speth R, Walther T. Angiotensin-(1-7) is an endogenous ligand for the G protein-coupled receptor Mas. Proc Natl Acad Sci U S A 100, 8258–8263, 2003.10.1073/pnas.143286910016621612829792Search in Google Scholar

Schiffrin EL, Thome FS, Genest J. Vascular angiotensin II receptors in renal and DOCA-salt hypertensive rats. Hypertension 5, 16–21, 1983.10.1161/01.HYP.5.6_Pt_3.V16Search in Google Scholar

Shapo L, Pomerleau J, McKee M. Epidemiology of hypertension and associated cardiovascular risk factors in a country in transition: a population based survey in Tirana City, Albania. J Epidemiol Community Health 57, 734–749, 2003.10.1136/jech.57.9.734173256812933782Open DOISearch in Google Scholar

Simoes E Silva AC, Miranda AS, Rocha NP, Teixeira AL. Renin angiotensin system in liver diseases: Friend or foe? World J Gastroenterol 23, 3396–3406, 2017.10.3748/wjg.v23.i19.3396544207628596676Open DOISearch in Google Scholar

Singh R, Singh AK, Alavi N, Leehey DJ. Mechanism of increased angiotensin II levels in glomerular mesangial cells cultured in high glucose. J Am Soc Nephrol 14, 873–880, 2003.10.1097/01.ASN.0000060804.40201.6E12660321Open DOISearch in Google Scholar

Slamkova M, Zorad S, Krskova K. Alternative renin-angiotensin system pathways in adipose tissue and their role in the pathogenesis of obesity. Endocr Regul 50, 229–240, 2016.2794117810.1515/enr-2016-002527941178Search in Google Scholar

Staessen J, Bulpitt CJ, Fagard R, Lijnen P, Amery A. The influence of menopause on blood pressure. J Hum Hypertens 3, 427–433, 1989.2607517Search in Google Scholar

Steckelings UM, Paulis L, Unger T, Bader M. Emerging drugs which target the renin-angiotensin-aldosterone system. Expert Opin Emerg Drugs 16, 619–630, 2011.10.1517/14728214.2011.61849521905943Open DOISearch in Google Scholar

Taurone S, Galli F, Signore A, Agostinelli E, Dierckx RA, Minni A, Pucci M, Artico M. VEGF in nuclear medicine: Clinical application in cancer and future perspectives (Review). Int J Oncol 49, 437–447, 2016.10.3892/ijo.2016.355327277340Search in Google Scholar

Townsend N, Wilson L, Bhatnagar P, Wickramasinghe K, Rayner M, Nichols M. Cardiovascular disease in Europe: epidemiological update 2016. Eur Heart J 37, 3232–3245, 2016.10.1093/eurheartj/ehw33427523477Search in Google Scholar

Wei Q, Sun J, Huang J, Zhou HY, Ding YM, Tao YC, He SM, Liu YL, Niu JQ. Prevalence of hypertension and associated risk factors in Dehui City of Jilin Province in China. J Hum Hypertens 29, 64–68, 2015.10.1038/jhh.2014.3224990419Search in Google Scholar

Ye G, Qin Y, Lu X, Xu X, Xu S, Wu C, Wang X, Wang S, Pan D. The association of renin-angiotensin system genes with the progression of hepatocellular carcinoma. Biochem Biophys Res Commun 459,18–23, 2015.10.1016/j.bbrc.2015.02.03025701390Search in Google Scholar

Yoshiji H, Kuriyama S, Yoshii J, Ikenaka Y, Noguchi R, Nakatani T, Tsujinoue H, Fukui H. Angiotensin-II type 1 receptor interaction is a major regulator for liver fibrosis development in rats. Hepatology 34, 745–750, 2001.10.1053/jhep.2001.2823111584371Search in Google Scholar

Yoshiji H, Yoshii J, Ikenaka Y, Noguchi R, Yanase K, Tsujinoue H, Imazu H, Fukui H. Suppression of the renin-angiotensin system attenuates vascular endothelial growth factor-mediated tumor development and angiogenesis in murine hepatocellular carcinoma cells. Int J Oncol 20, 1227–1231, 2002.1201200310.3892/ijo.20.6.1227Search in Google Scholar

Zhang X, Lassila M, Cooper ME, Cao Z. Retinal expression of vascular endothelial growth factor is mediated by angiotensin type 1 and type 2 receptors. Hypertension 43, 276–281, 2004.1471835110.1161/01.HYP.0000113628.94574.0f14718351Search in Google Scholar

Zhao Y, Adjei AA. Targeting Angiogenesis in Cancer Therapy: Moving Beyond Vascular Endothelial Growth Factor. Oncologist 20, 660–673, 2015.10.1634/theoncologist.2014-0465457178326001391Search in Google Scholar