Possible association of ghrelin/obestatin balance with cardiometabolic risk in obese subjects with Helicobacter pylori

Aydemir S, Bayraktaroglu T, Sert M, Sokmen C, Atmaca H, Mungan G, Gun BD, Borazan A, Ustundag Y. The effect of Helicobacter pylori on insulin resistance. Dig Dis Sci 50, 2090–2093, 2005.10.1007/s10620-005-3012-z16240220Open DOISearch in Google Scholar

Azuma T, Suto H, Ito Y, Ohtani M, Dojo M, Kuriyama M, Kato T. Gastric leptin and Helicobacter pylori infection. Gut 49, 324–329, 2001.10.1136/gut.49.3.324172844011511551Search in Google Scholar

Boltin D, Niv Y. Ghrelin, Helicobacter pylori and body mass: is there an association? Isr Med Assoc J 14, 130–132, 2012.Search in Google Scholar

Burtis CA, Ashwood ER, Bruns DE. Tietz Textbook of Clinical Chemistry and Molecular Diagnostics (4^th Ed.). Elsevier, Saunders, St. Louis, 2006.Search in Google Scholar

Buzas GM. Metabolic consequences of Helicobacter pylori infection and eradication. World J Gastroenterol 20, 5226–5234, 2014.10.3748/wjg.v20.i18.5226401703724833852Open DOISearch in Google Scholar

Campana D, Nori F, Pagotto U, De Iasio R, Morselli-Labate AM, Pasquali R, Corinaldesi R, Tomassetti P. Plasma acylated ghrelin levels are higher in patients with chronic atrophic gastritis. Clin Endocrinol (Oxf), 67, 761–766, 2007.10.1111/j.1365-2265.2007.02959.x17614968Search in Google Scholar

Carabotti M, D’Ercole C, Iossa A, Corazziari E, Silecchia G, Severi C. Helicobacter pylori infection in obesity and its clinical outcome after bariatric surgery. World J Gastroenterol 20, 647–653, 2014.10.3748/wjg.v20.i3.647392147424574738Open DOISearch in Google Scholar

Chen CY, Asakawa A, Fujimiya M, Lee SD, Inui A. Ghrelin gene products and the regulation of food intake and gut motility. Pharmacol Rev 61, 430–481, 2009.10.1124/pr.109.00195820038570Open DOISearch in Google Scholar

Chevenne D, Letailleur A, Trivin F, Porquet D. Effect of hemolysis on the concentration of insulin in serum determined by RIA and IRMA. Clin Chem 44, 354–356, 2001.10.1093/clinchem/44.2.354Search in Google Scholar

Cho I, Blaser MJ, François F, Mathew JP, Ye XY, Goldberg JD, Bini EJ. Helicobacter pylori and overweight status in the United States: data from the third national health and nutrition examination survey. Am J Epidemiol 162, 579–84, 2005.10.1093/aje/kwi23716093294Search in Google Scholar

Choe YH, Lee JH, Lee HJ, Paik KH, Jin DK, Song SY, Lee JH. Ghrelin levels in gastric mucosa before and after eradication of H. pylori. Gut and Liver 1, 132–137, 2007.10.5009/gnl.2007.1.2.132287163120485629Search in Google Scholar

Choi J, Ko K, Lim J, Cheon E, Lee G, Yoon J. The association between Helicobacter pylori infection and body weight among children. Pediatr Gastroenterol Hepatol Nutr 19, 110–115, 2016.10.5223/pghn.2016.19.2.110494230827437187Search in Google Scholar

Chuang CH, Sheu BS, Yang HB, Lee SC, Kao AW, Cheng HC, Chang WL, Yao WJ. Gender difference of circulating ghrelin and leptin concentrations in chronic Helicobacter pylori infection. Helicobacter 14, 54–60, 2009.10.1111/j.1523-5378.2009.00653.xOpen DOISearch in Google Scholar

Cindoruk M, Yetkin I, Deger SM, Karakan T, Kan E, Unal S. Influence of H. pylori on plasma ghrelin in patients without atrophic gastritis. World J Gastroenterol 13, 1595–1598, 2007.10.3748/wjg.v13.i10.1595Open DOISearch in Google Scholar

Deng ZH, Chu B, Xu YZ, Zhang B, Jiang LR. Influence of H. pylori infection on Ghrelin levels in children. World J Gastroenterol 18, 5096–5100, 2012.10.3748/wjg.v18.i36.5096Open DOISearch in Google Scholar

Du T, Sun X, Yin P, Huo R, Ni C, Yu X. Increasing trends in central obesity among Chinese adults with normal body mass index, 1993–2009. BMC Public Health 13, 327, 2013.10.1186/1471-2458-13-327Search in Google Scholar

Ericksen RE, Rose S, Westphalen CB, Shibata W, Muthupalani S, Tailor Y, Friedman RA, Han W, Fox JG, Ferrante AW Jr, Wang TC. Obesity accelerates Helicobacter felis-induced gastric carcinogenesis by enhancing immature myeloid cell trafficking and TH17 response. Gut 63, 385–394, 2014.10.1136/gutjnl-2013-305092Open DOISearch in Google Scholar

Fernandez-Real JM, Pickup JC. Innate immunity, insulin resistance and type 2 diabetes. Trends Endocrinol Metab 19, 10–16, 2008.10.1016/j.tem.2007.10.004Search in Google Scholar

Fujiwara Y, Higuchi K, Arafa UA, Uchida T, Tominaga K, Watanabe T, Arakawa T. Long-term effect of Helicobacter pylori eradication on quality of life, body mass index, and newly developed diseases in Japanese patients with peptic ulcer disease. Hepatogastroenterology 49, 1298–1302, 2002.Search in Google Scholar

Garrow JS, Webster J. Quetelet’s index (W/H2) as a measure of fatness. Int J Obes 9, 147–153, 1985.Search in Google Scholar

Gen R, Demir M, Ataseven H. Effect of Helicobacter pylori eradication on insulin resistance, serum lipids and lowgrade inflammation. South Med J 103, 190–196, 2010.10.1097/SMJ.0b013e3181cf373fSearch in Google Scholar

Gokcel A, Gumurdulu Y, Kayaselcuk F, Serin E, Ozer B, Ozsahin AK, Guvener N. Helicobacter pylori has no effect on plasma ghrelin levels. Eur J Endocrinol 148, 423–442, 2003.10.1530/eje.0.1480423Search in Google Scholar

Goodwin CS, Mendall MM, Northfield TC. Helicobacter pylori infection. Lancet 349, 265–269, 1997.10.1016/S0140-6736(96)07023-7Search in Google Scholar

Hassouna R, Zizzari P, Tolle V. The ghrelin/obestatin balance in the physiological and pathological control of growth hormone secretion, body composition and food intake. J Neuroendocrinol 22, 793–804, 2010.10.1111/j.1365-2826.2010.02019.x20456603Search in Google Scholar

Huda MS, Durham BH, Wong SP, Deepak D, Kerrigan D, McCulloch P, Ranganath L, Pinkney J, Wilding JP. Plasma obestatin levels are lower in obese and post-gastrectomy subjects, but do not change in response to a meal. Int J Obes 32, 129–135, 2008.10.1038/sj.ijo.080369417667911Search in Google Scholar

Cui H, Lopez M, Rahmouni K. The cellular and molecular bases of leptin and ghrelin resistance in obesity. Nat Rev Endocrinol 13, 338–351, 2017.10.1038/nrendo.2016.222890408328232667Open DOISearch in Google Scholar

Jeffery PL, McGuckin MA, Linden SK. Endocrine impact of Helicobacter pylori: focus on ghrelin and ghrelin oacyltransferase. World J Gastroenterol 17, 1249–1260, 2011.10.3748/wjg.v17.i10.1249306825921455323Open DOISearch in Google Scholar

Khosravi Y, Bunte RM, Chiow KH, Tan TL, Wong WY, Poh QH, Doli Sentosa IM, Seow SW, Amoyo AA, Pettersson S, Loke MF, Vadivelu J. Helicobacter pylori and gut microbiota modulate energy homeostasis prior to inducing histopathological changes in mice. Gut Microbes 7, 48–53, 2016.10.1080/19490976.2015.1119990485646426939851Search in Google Scholar

Kim TJ, Lee H, Kang M, Kim JE, Choi YH, Min YW Min BH, Lee JH, Son HJ, Rhee PL, Baek SY, Ahn SH, Kim JJ. Helicobacter pylori is associated with dyslipidemia but not with other risk factors of cardiovascular disease. Sci Rep 6, 38015, 2016.10.1038/srep38015512509227892538Search in Google Scholar

Lee ES1, Yoon YS, Park CY, Kim HS, Um TH, Baik HW, Jang EJ, Lee S, Park HS, Oh SW. Eradication of Helicobacter pylori increases ghrelin mRNA expression in the gastric mucosa. J Korean Med Sci 25, 265–271, 2010.10.3346/jkms.2010.25.2.265281129520119581Search in Google Scholar

Matthews DR, Hosker JP, Rudenski AS, Naylor BA, Treacher DF, Turner RC. Homeostasis model assessment: insulin resistance and beta-cell function from fasting plasma glucose and insulin concentrations in man. Diabetologia 28, 412–419, 1985.10.1007/BF002808833899825Open DOISearch in Google Scholar

Stec-Michalska K, Malicki S, Michalski B, Peczek L, Wisniewska-Jarosinska M, Nawrot B. Gastric ghrelin in relation to gender, stomach topography and Helicobacter pylori in dyspeptic patients. World J Gastroenterol 15, 5409–5417, 2009.10.3748/wjg.15.5409277809619916170Open DOISearch in Google Scholar

Nwokolo CU, Freshwater DA, O’Hare P, Randeva HS. Plasma ghrelin following cure of Helicobacter pylori. Gut 52, 637–640, 2003.10.1136/gut.52.5.637177363412692045Search in Google Scholar

Osawa H, Nakazato M, Date Y, Kita H, Ohnishi H, Ueno H, Shiiya T, Satoh K, Ishino Y, Sugano K. Impaired production of gastric ghrelin in chronic gastritis associated with Helicobacter pylori. J Clin Endocrinol Metab 90, 10–16, 2005.10.1210/jc.2004-133015483107Open DOISearch in Google Scholar

Osawa H. Ghrelin and Helicobacter pylori infection. World J Gastroenterol 14, 6327–6333, 2008.10.3748/wjg.14.6327276611319009647Open DOISearch in Google Scholar

Quatrini M, Boarino V, Ghidoni A, Baldassarri AR, Bianchi PA, Bardella MT. Helicobacter pylori prevalence in patients with diabetes and its relationship to dyspeptic symptoms. J Clin Gastroenterol 32, 215–217, 2001.10.1097/00004836-200103000-0000611246346Open DOISearch in Google Scholar

Satoh H, Saijo Y, Yoshioka E, Tsutsui H. Helicobacter Pylori infection is a significant risk for modified lipid profile in Japanese male subjects. J Atheroscler Thromb 17, 1041–1048, 2010.10.5551/jat.515720610892Open DOISearch in Google Scholar

Sotiropoulos A, Gikas A, Skourtis S, Merkouris P, Pentzeridis P, Polydorou A, Pappas S. Seropositivity to Chlamydia pneumoniae or Helicobacter pylori and coronary artery disease. Int J Cardiol 109, 420–421, 2006.10.1016/j.ijcard.2005.05.03915993502Search in Google Scholar

Wallace TM, Levy JC, Matthews DR. Use and abuse of HOMA modeling. Diabetes Care 27, 1487–1495, 2004.10.2337/diacare.27.6.148715161807Open DOISearch in Google Scholar

Ulasoglu C, Isbilen B, Doganay L, Ozen F. Effect of Helicobacter pylori eradication on serum ghrelin and obestatin levels. World J Gastroenterol 19, 2388–2394, 2013.10.3748/wjg.v19.i15.2388363199223613634Open DOISearch in Google Scholar

Yildiz B, Suchard M, Wong M, McCann S, Licinio J. Alterations in the dynamics of circulating ghrelin, adiponectin, and leptin in human obesity. Proc Natl Acad Sci USA 101, 10434–10439, 2004.10.1073/pnas.040346510147860115231997Search in Google Scholar

Zhang JV, Ren PG, Avsian-Kretchmer O, Luo CW, Rauch R, Klein C, Hsueh AJ. Obestatin, a peptide encoded by the ghrelin gene, opposes ghrelin’s effects on food intake. Science 310, 996–999, 2005.10.1126/science.111725516284174Search in Google Scholar

Zhang Y, Du T, Chen X, Yu X, Tu L, Zhang C. Association between Helicobacter pylori infection and overweight or obesity in a Chinese population. J Infect Dev Ctries 9, 945–953, 2015.10.3855/jidc.603526409735Search in Google Scholar