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Introduction

Hospitals are known to use many products. The hospital staff responsible for managing products are constantly handling supply shortages and other logistical problems and challenges (Tucker & Edmondson, 2003).

To avoid supply shortages and improve cost control, many studies focused on optimising hospital inventory. Examples of such studies can be seen in the work by Varghese, Rossetti, Pohl, Apras, and Marek (2012) and Kritchanchai and Meesamut (2015). The latter identified potential cost savings of 14%. Besides this research on savings, it was found that proper hospital logistics handling helps to improve job satisfaction among the nursing staff (Landry & Beaulieu, 2013). One possible way to improve logistics performance is to reduce the number of products used in hospitals (Wan et al., 2012). This idea could be further elaborated considering the product variety, i.e., the range of products within a given group.

It is up to the medical staff to determine the demand for various devices as well as single-use medical products. However, not many (if any) among the medical staff have training in inventory handling. In general, their experience is that the available equipment is essential. Therefore, they tend to overestimate the need for the equipment based on an "in case of" strategy. For single-use products, such as bandages and compresses, one may discuss how many sizes and what kinds are necessary without having an impact on the quality of performed medical procedures.

The relevant question is whether there is a need for all sizes and types within a given product group. For example, for one type of bandages, a hospital may use five sizes. The largest and smallest of these may be used only once a year, resulting in waste due to the expiry date. Instead of having all sizes, one may substitute a smaller-size product with a large-size product, for example, a large bandage can be used on a smaller injury. This way, it is possible to substitute large and small bandages.

Current research (including the studies mentioned earlier) does not address these issues of product groups and product variety to the needed extent. This paper proposes a substitution method and investigates the effect on cost made by the substitution of an item with a similar item within a product group. The data used in this paper was collected from a rural hospital in Norway.

This paper is organised as follows. Section 1 provides a review of the literature on inventory management and product variety. Section 2 describes the data used in the research. Section 3 describes the substitution model developed for this study. Section 4 presents the results, which are further discussed in Section 5. Finally, the concluding comments and possible future research directions are presented.

Literature review

In general, hospitals are complex organisations that consist of various units, including those that provide various medical services to patients and those that are non-medical, such as administration, housekeeping etc. Each of these units performs distinctive functions, which require unique products. Thus, a hospital must maintain a considerable inventory, which results in high expenditures. Many studies indicate hospitals spending 25% to 30% of their budget on purchasing and handling the inventory (Ozcan, 2005).

Several inventory management methods have been developed for the reduction of costs and streamlining the inventory distribution process. Inventory optimisation is one of the most common methods to ensure the cost-effective management of inventory. The researchers Varghese et al. (2012) presented a case study for optimising inventory with the help of the r, Q inventory policy, based on which an order of Q quantities is placed for each r period. In this study, the authors found potential savings amounting to 14% from inventory present in the hospital's distribution centre. Similar savings were identified in the study conducted by Kritchanchai and Meesamut (2015). The authors developed an inventory planning model for "A" class products (high consumption) involving various inventory policies. In addition, the research pointed out the reduction of product shortage by 92.98%. One of the benefits of proper inventory management is the reduction of the inventory value present in the system. The authors Rachmania and Basri (2013) demonstrated a 50% reduction in the inventory value of oncology medications at a public hospital in Indonesia by using the s, Q policy, based on which an order of Q quantities is placed when the current stock level reaches s quantities.

The nature of hospital logistics is complex and multi-faceted. The propriety of managing the operations may benefit from exploring and adopting policies from logistics in other sectors. One such policy is the consideration of the product variety, which significantly impacts organisations in terms of profits and various supply-chain parameters. The research conducted by Wan et al. (2012) showed the importance of careful planning in terms of the level of product variety for organisations. The authors looked into a soft drink bottler with 108 distribution centres and found that the product variety had a direct negative effect on the fill rate of products, whereas the product sales were affected both directly and indirectly by the product variety. As product variety increases, the product sales initially increase as well, and after a certain point, the sales fall.

The product must be understood before making changes in the product variety at hospitals. One of the most straightforward approaches is the product hierarchy method proposed by (Malone, 1987). This approach was also used in the research by Fujita, Sakaguchi, and Akagi (1999) for product design and development, and in the article by Wang et al. (2011) for product manufacturing. These studies used a product hierarchy of three levels. The top level was comprised of the product family, which was followed by the product group or module, and finally, the product or module variants.

Erens and Verhulst (1997) mapped products based on the required function, technological realisation, and physical realisation. Fujita et al. (1999) used a similar concept; however, they defined the customer, function, and manufacturing viewpoints. The authors employed a binary integer programming model together with a specialised algorithm for the optimisation of the product variety. This research was performed in a company that designed television receiver circuits.

In several other studies, the issue of product variety was addressed with the help of the 0 - 1 integer programming approach. In the context of manufacturing, Wang et al. (2011) developed an optimisation problem to explore trade-offs between the product variety and the manufacturing complexity in the design of a mixed-model assembly system. The decision-making complexity of this research was related to the selection of best product variants to be manufactured on the assembly line considering various costs associated with their production. The main requirement for the optimisation of the product variance was to achieve the highest customer market share. Similar work was also conducted by Nishino, Takenaka, Koshiba, and Kodama (2014); however, this research dealt with the service industry.

Several researchers demonstrated the use of integer programming for product variety problems in the retail sector. In the work of McBride and Zufryden (1988), the product variety reduction was made based on customer preference. Borin, Farris, and Freeland (1994) came up with a decision-making framework based on the assortment and space allocation for products. Jayaraman, Srivastava, and Benton (1998) developed a non-linear optimisation model for the product variety, also considering inventory and product brands. The authors concluded that as the budget increased, the product variety could also be increased for achieving the desired profit for the retailer.

To sum up, the research in the areas of logistics for such contexts as manufacturing and retail has clearly demonstrated the benefits of carefully considered product variety. However, the area of hospital inventory management has not yet seen an in-depth study on the product variety. Therefore, the research presented in this paper aims to explore the reduction in the product variety combined with the inventory optimisation using a brute force analysis. The developed model and the results presented further contribute to the understanding of the effect made by the product variety and possible product substitutions on the inventory costs of hospitals.

Research data

The data was collected in a small rural hospital in Norway. The external order data for the duration of six years (2010-2015) was taken from the central database of the hospital. Each year, the hospital makes more than 6 000 external orders for a total of 2 331 products, of which 1 645 are sterile, and 686 are non-sterile. Currently, the hospital uses a two-level product hierarchy. The products are classified into ten product families, such as laboratory supplies, medical disposables, office supplies etc.

As defined in the literature, the product architecture, includes at least three levels, namely, the product family, the product group, and the product (Fujita et al., 1999). With the help of product mapping, an intermediate level was defined and named product groups, based on the function of the product. These product groups contained products which differed only by characteristics. In total, 1 481 product groups of sterile products and 532 product groups of non-sterile products were created. The values of product substitution factors used further in the model were defined manually based on product attributes such as size and quantity. Currently, the hospital does not optimise its inventory management. The model, which is developed and proposed further, addresses the issue of product variety and inventory optimisation.

Substitution modelling

Since the hospital uses a two-level hierarchy system for products, the authors of this article developed an intermediate level and called it "the product group." This level will help the study into the product variety as it is intended for products which are used for the same purpose but differ based on their characteristics. For example, assume a hospital uses blister adhesive bandages of two different pack sizes 6 and 12, which belong in the product family of medical consumables. Therefore, in the product analysis, these two products can belong to a single group. Here, the quantity required for the substitution of one product with another varies; this can be termed many-to-one substitution. This many-to-one substitution makes it difficult to understand the effect of the product variety at hospitals. To understand this effect, the substitution model was developed and presented. This substitution model uses notations provided in Table 1.

Notations used in the substitution model

NOTATIONDESCRIPTION
NTotal number of products within the product group
i, jProduct number within the product group; i, j ∈ (1,...,N)
PNotation used for product usage number
MNotation used for the design point
Uip$U_{i}^{p}${1,0,$\left\{ \begin{matrix}1, \\0, \\\end{matrix} \right.$if product i within the product group is used in the product usage number Otherwise
UiM$U_{i}^{M}${1,0,$\left\{ \begin{matrix}1, \\0, \\\end{matrix} \right.$if product / within the product group is used in the design point M Otherwise
UjM$U_{j}^{M}${1,0,$\left\{ \begin{matrix}1, \\0, \\\end{matrix} \right.$if product j within the product group is used in the design point M Otherwise
WjiM$W_{ji}^{M}$if product j within the product group is used in the design point M where UjM$U_{j}^{M}${1,0,$\left\{ \begin{matrix}1, \\0, \\\end{matrix} \right.$Otherwise
SijM$S_{ij}^{M}${X,0,$\left\{ \begin{matrix}\text{X,} \\0, \\\end{matrix} \right.$if x units of product i can substitute 1 unit of product j within the product group at the design point M Otherwise
Where x is a real number
RijM$R_{ij}^{M}${1,ifSijM00,ifSijM=0$\left\{ \begin{array}{*{35}{l}}1, & \text{if}\,S_{ij}^{M}\ne 0 \\0, & \text{if}\,S_{ij}^{M}=0 \\\end{array} \right.$
IDi$I{{D}_{i}}$Initial demand of product i within the product group
CDiM$CD_{i}^{M}$Modified demand of product i within the product group at the design point M with the replacement factor
DiM$D_{i}^{M}$Modified demand of product i within the product group at the design point M with the conversion factor
LCiM$LC_{i}^{M}$Logistics cost of product i within the product group at the design point M
TCiM$TC_{i}^{M}$Total cost of product i within the product group at the design point M
LCM$L{{C}^{M}}$Summation of logistics cost of products in the product group at the design point M
TCM$T{{C}^{M}}$Summation of the total cost of products in the product group at the design point M

A product group consists of N products, which creates 2N possible ways to use products within this product group. This is similar to the 2k factorial design, which is commonly mentioned in the literature on the design of experiments (Sanchez, 2005). Table 2 represents the product selection for a product group of three products.

Product usage for a product group containing three products

PRODUCT USAGE NUMBERU1U2U3
0000
1100
2010
3110
4001
5101
6011
7111

A simple condition in product usage is that at least one product in a product group must be used for each design point. The equation (1) represents this rule.

i=1NUip1$$\sum\limits_{i=1}^{N}{U_{i}^{p}}\ge 1$$

Therefore, product usage number 0 becomes invalid. Thus, this reduces the number of possibilities from eight to seven. Therefore, the number of possibilities for a product group with N products is 2N - 1.

Estimated product substitution

For most of the product usage numbers, there are one or more unused products. In these instances, their demand must be substituted for by another product. Therefore, irrespective of whether a product can substitute for another product, demand substitution is done. For simplification purposes, a simple rule applies that only one product can be used to substitute for another product for a design point and, thus, invalidates the partial substitutions. Therefore, the number of substitutions is equal to the number of products unused in a design point. This is represented in equations (2) and (3).

i=1NWjiM=1,J:UjM=0$$\sum\limits_{i=1}^{N}{W_{ji}^{M}}=1,\,\forall J:U_{j}^{M}=0$$i=1Nj=1NWjiM=N-i=1NUiM$$\sum\limits_{i=1}^{N}{\sum\limits_{j=1}^{N}{W_{ji}^{M}}}=N\text{-}\,\sum\limits_{i=1}^{N}{U_{i}^{M}}$$Numberofdesignpoints=(i=1TUiM)Ni=1NUiM$$\text{Number}\,\text{of}\,\text{design}\,\text{points}={{\left( \sum\limits_{i=1}^{T}{U_{i}^{M}} \right)}^{N-\sum{_{i=1}^{N}U_{i}^{M}}}}$$

For each product usage number, there are various possibilities of product substitutions, for example, in a product group containing three products, when two of the products are selected for usage, and one is unused. In this example, either of the other two products, i.e., two different combinations, occur for this possibility of substituting the demand of the unused product. Based on this, the number of possibilities that occur for each product usage number is represented in equation (4). Table 3 presents the number of possibilities of product usage and several design points based on the size of the product group.

Number of possible product usage and design points based on size of product groups

SIZE OF PRODUCT GROUPNO. OF POSSIBLE PRODUCT USAGENo. OF DESIGN POINTS
111
233
3710
531196
825541393
1010232237921
15327671.39 * 1011

Table 4 presents the usage of products with the notation Ui and product substitution with the notation Wij for a product group of three products.

Design points for a product group of three products

DESIGN POINTSU1U2U3W1JW2JW3J
1,11000 1 10 0 00 0 0
2,10100 0 01 0 10 0 0
3,11100 0 10 0 00 0 0
3,21100 0 00 0 10 0 0
4,10010 0 00 0 01 1 0
5,11010 1 00 0 00 0 0
5,21010 0 00 0 00 1 0
6,10110 0 01 0 00 0 0
6,20110 0 00 0 01 0 0
7,11110 0 00 0 00 0 0
Product replacement constraint

The next step is to make sure that the design points are valid. For this, a new variable CD (Demand check of product i in design point M) is introduced. The calculation for this variable is presented in equation (5). If a product i substitutes for another product j in a design point, then the demand of product j is added to the demand of product i. For a design point, the summation of demands of all products is equated to the summation of check demand. If this is true, then the design point is valid. This is to make sure that the demand for unused

CDiM=UiM[IDi+j=1N(1-UjiM)WjiMRijMIDi]$$CD_{i}^{M}=U_{i}^{M}\left[ I{{D}_{i}}+\sum\limits_{j=1}^{N}{\left( 1\text{-}\,\,U_{ji}^{M} \right)W_{ji}^{M}R_{ij}^{M}I{{D}_{i}}} \right]$$

products is satisfied with other products. It is represented by equation (6).

i=1NCDiM=i=1NIDi$$\sum\limits_{i=1}^{N}{CD_{i}^{M}}=\sum\limits_{i=1}^{N}{I{{D}_{i}}}$$
Modified demand

For all the valid design points, the new demand for the products in the product group is calculated by equation (7). The difference between equations (6) and (7) is the usage of the replacement factor and the substitution factor, respectively.

DiM=UiM[IDi+j=1N(1-UjM)WjiMSijMIDj]$$D_{i}^{M}=U_{i}^{M}\left[ I{{D}_{i}}+\sum\limits_{j=1}^{N}{\left( 1\text{-}\,\,U_{j}^{M} \right)W_{ji}^{M}S_{ij}^{M}I{{D}_{j}}} \right]$$
Cost calculation

The ordering quantity for the modified demand is calculated based on the economic order quantity and cost functions under the stochastic condition. The objective is to find the values of cost for a product group for each design point, as shown in equations (8) and (9).

LCM=i=1NLCiM$$L{{C}^{M}}=\sum\limits_{i=1}^{N}{LC_{i}^{M}}$$TCM=i=1NTCiM$$T{{C}^{M}}=\sum\limits_{i=1}^{N}{TC_{i}^{M}}$$
Results

The model was programmed using Microsoft Excel and the visual basic application (VBA) language. Assumptions made for the study are listed below.

Carrying charge for the products was 20%.

Expected length of lead-time of 3 days and the standard deviation of 0 days was considered for products for which the supplier details were missing.

Product substitution effect

One of the focus points for the research is to understand the product substitution effect. Here, the results are presented for both types of substitution, namely one-to-one substitution and many-to-one substitution. For this, the authors of this article used a non-sterile product group containing products that differ by colour for one-to-one substitution, and a sterile product group containing products that differ by size for many-to-one substitution.

One-to-one substitution

The notation NSPi is used to represent the non-sterile product group, where i represents the product number within the product group. Since products within the product group differ based on colour, the substitution factor between these products is one. The initial details of the products in this product group are presented in Table 5.

Initial details of products within the non-sterile product group

DEMANDAVG. UNIT COST
NSP1260NOK* 0.172
NSP2461NOK 0.127
NSP3162NOK 0.133

• Conversion rate as on 21.12.2019: 1 NOK = 0.11 USD Source: https://www.xe.com/

Earlier, the authors of the article presented all the design points for a product group of three products in Table 4. The hospital currently uses all the products within the product group, which is formed in the design point (7, 1). In this design point, the net logistics cost accounts to NOK 205.66 and the total cost accounts to NOK 330.49, which is presented in Table 6. Both these costs will act as a baseline for cost comparisons.

Cost when all the products in the product group are used

DESIGN POINT: (7, 1)NSPjNSP2NSP3TOTAL
Demand (Units)260461162883
Logistics Cost (NOK)72.4382.9450.28205.66
Total Cost (NOK)117.13141.5271.84330.49

In the remaining nine design points, at least one product is unused, and another product substitutes for its demand. For the design points (1, 1), (2, 1) and (4, 1), only one product is used, and in the remaining six design points, two products are used. The summary of the values of the added demand together with the related costs and the potential savings are provided in Table 7. The usage of only product NSP2 occurring in the design point (2, 1) had a potential saving of 31% of the total cost. As the results suggest, the reduction of any product in this product group would result in minimum savings of 4%. Therefore, at least one product should be given up in this product group to save cost.

Cost when products are reduced from product group

DESIGN POINT(1,1)(2,1)(3,1)(3,2)(4,1)(5,1)(5,2)(6,1)(6,2)
DescriptionNSP1 is used. NSP2 & NSP3 are substituted by NSP1NSP2 is used. NSP1 & NSP3 are substituted by NSP2NSP1 &NSP2 are used. NSP3 is substituted by NSP1NSP1& NSP2 are used. NSP3 is substituted by NSP2NSP3 is used. NSP1 & NSP2 are substituted by NSP3NSP1 & NSP3 are used. NSP2 is substituted by NSP1NSP1 & NSP3 are used. NSP2 is substituted by NSP3NSP2 & NSP3 are used. NSP1 is substituted by NSP2NSP2 & NSP3 are used. NSP1 is substituted by NSP3
ProductNSP1NSP2NSP3NSP1NSP2NSP3NSP1NSP2NSP3NSP1NSP2NSP3NSP1NSP2NSP3NSP1NSP2NSP3NSP1NSP2NSP3NSP1NSP2NSP3NSP1NSP2NSP3
Initial Demand(Units)260000461026046102604610001622600162260016204611620461162
Added Demand(Units)523000422016200016200072146100004610260000260
Modified Demand(Units)883000883042246102606230008837210162260062307211620461422
Logistics Cost of Products(NOK)133.390.000.000.00114.730.0092.2582.940.0072.4396.40.000.000.00117.31120.540.0050.2872.430.0098.550.00103.6950.280.0082.9481.12
Total Cost of Products(NOK)285.190.000.000.00226.940.00164.8141.520.00117.13175.560.000.000.00234.82244.490.0071.84117.130.00181.460.00195.3171.840.00141.52137.28
Logistics Cost for Product Group(NOK)133.39114.73175.19168.83117.31170.82170.98153.97164.06
Total Cost for Product Group(NOK)285.19226.94306.32292.69234.82316.33298.59267.15278.8
% saving Logistics Cost35.1444.2114.8117.9142.9616.9416.8625.1320.23
% saving Total Cost13.7131.337.3111.4428.954.299.6519.1715.64
Many-to-one substitution

The notation SPi is used to represent the sterile product group, where i represents the product number within the product group. The selected product group contains two products within the product group. Table 8 presents the demand and unit cost for the products in the product group.

Initial data of the product group

DEMANDAVG. UNIT COST
SP150NOK 54.95
SP237NOK 73.53

The products in this product group differ based on size. Consequently, the product substitution factor may or may not be one. Table 9 shows the product substitution factor for both the products in the product group.

Substitution factor of the product group

SP1SP2
SP112
SP211

At present, the hospital uses both products in the product group, which is formed in the design point (3, 1). The costs in this instance will be the reference for making the cost-saving calculation. The net logistics cost is NOK 1 153.31, and the total cost is NOK 6 621.15, which is represented in Table 10.

Cost when both products are used

DESIGN POINT: (3,1)SP1Sp2TOTAL
Demand (Units)503787
Logistics Cost (NOK)577.20576.111 153.31
Total Cost (NOK)3 324.463 296.706 621.15

Since this product group contains only two products, a reduction can occur by one product generated in two design points (1, 1) and (2, 1). This reduction of the product in both design points results, in logistics cost savings amounting to more than 20% and an increase in the total cost due to the product cost. These results are presented in Table 11. Therefore, for this product group, both products should be used. This product group was chosen to demonstrate the effect of product substitution factor.

Cost when only one product is used

DESIGN POINT(1,1)(2,1)
DescriptionSP1 is used. SP2 is substituted by SP1SP2 is used. SP1 is substituted by SP2
ProductSP 1SP2SP1SP2
Initial Demand(Units)500037
Added Demand(Units)740050
Modified Demand(Units)1240087
Logistics Cost of Products(NOK)903.110.000.00876.99
Total Cost of Products(NOK)7 716.300.000.007 274.05
Logistics Cost for Product Group(NOK)903.11876.99
Total Cost for Product Group(NOK)7 716.307 274.05
% saving Logistics Cost21.6923.96
% saving Total Cost- 16.54-9.86
Overall results

For each product group, the design point creating the lowest total cost is selected for summarisation of the results. The summary is presented in Table 12. For this hospital, the model generates a reduction of 262 items with a potential cost saving of 22.3% which is an increase of 3.80% when the inventory is optimised. The split up of the results shows that the sterile products provide cost saving of 22.97% whereas the non-sterile products generate only 13.43% in cost savings.

Overall results

STERILENON-STERILETOTAL
Current ProcessNumber of Products16456862331
Logistics Cost (NOK)2 027 4371 240 1023 267 540
Total Cost (NOK)9 890 4396 334 96416 225 404
All products used with optimised InventoryNumber of Products16456862331
% reduction in number of Products0.000.000.00
Logistics Cost (NOK)663 507245 603909 110
% reduction in logistics Cost67.2780.1972.18
Total Cost (NOK)7 651 8305 572 99013 224 820
% reduction in total Cost22.6312.0318.49
Substitution ModelNumber of Products15245452069
% reduction in number of Products7.3620.5511.24
Logistics Cost (NOK)636 228215 468851 696
% reduction in logistics Cost68.6282.6273.93
Total Cost (NOK)7 123 5965 483 92712 607 523
% reduction in total Cost27.9713.4322.30
Discussion

In this hospital, the number of sterile products used is more than twice the number of non-sterile products used. A baseline was demonstrated to provide the potential of the reduction in the product variety for this hospital. Approximately 7% of sterile products and 21% of non-sterile products could be reduced. Therefore, more than 11% of product varieties may be reduced. Since two different types of product substitution were explored, they should be discussed individually.

For one-to-one product substitution, a non-sterile product group containing three products was inspected. When all the products were used, the logistics cost was NOK 205.66, and the total cost was NOK 330.49. With the reduction of just one product, there was a drop in both the logistics costs and the total costs. The drop in the logistics cost was 14% - 25%, and the drop in the total cost was 4% - 19%. This difference occurred due to the presence of product cost. The substitution of the product NSP1 by NSP2 and the usage of NSP3 showed better results. When there was the usage of only one product, the logistics cost decreased somewhat between 35% - 44% and the total cost decreased by 13% - 31%. The usage of only NSP2 alone gave better results. Due to the variation in the cost per product of NSP2 and NSP3 in the third decimal place, NSP2 gave better results. In other words, the selection of the product with the lowest cost per product value yielded better results. This simplification was possible because the substitution factor between the products was one.

For many-to-one product substitution, a sterile product group containing two products was examined. When both products were used, the logistics cost was NOK 1 153.31, and the total cost was NOK 6 621.15. When only one product in the product group was used, the logistics cost dropped between 21% - 24%, whereas the total cost increased between 9% - 17%. The drop in the logistics cost was possible because of pooling the demands of products. The increase in the total cost occurred due to the combination of both cost per product and the substitution factor. When SP1 was used, the cost of product SP2 was NOK 73.53, and the product of the substitution factor when SP2 was substituted with SP1, and the cost per product of SP1 was NOK 109.90. The cost per product of SP2 was higher than that of SP1. Therefore, in both these instances, it resulted in a higher total cost when compared to the usage of both products. Since this product group contained only two products, the comparisons were easier. It would become more complex with the increase in the size of a product group.

The overall result shows that 262 (11%) product varieties could be reduced, resulting in a cost-saving of more than NOK 3.6 million (22.3%). According to research by Wan et al. (2012), the sales of products increase with the increase in the product variety until it reaches an optimum point and then decrease. Similarly, these results indicate that the reduction of all varieties in the product group does not yield cost reduction. The costs saved at this hospital are rather small, but on the scale of all 85 hospitals in Norway, it would result in approx. NOK 307.5 million. Thus, the study into the product variety of inventory at hospitals can bring considerable cost savings.

Conclusions

This paper investigated the influence of the product variety on hospital inventory based on the product substitution factor and the corresponding inventory cost. After the discussion of the literature, the developed model for the study was presented. This model is universal in nature and can be used in other fields, such as retail, marketing etc. The developed model contributes to the pool of literature focusing on the analysis decision-making with respect to product variety based on product attributes as well as inventory management. The influence of the substitution factor on the product variety decision was presented together with the corresponding inventory cost. The results showed a combined influence of the product substitution factor and the product unit cost.

Various additional aspects may be considered to contribute to the knowledge of the effects of the product variety on the inventory of hospitals. One of the limitations of the research presented in this article is that it does not address issues such as time taken by healthcare personnel to adapt to this change or flexibility of the hospital and other factors. Among other limitations, this research does not consider the replenishment coordination and floor space limitations. Future research may focus on having these aspects included in modelling to produce better real-time results. This research also does not account for healthcare personnel's preference for products. This aspect may prove to be a crucial factor influencing the implementation of the produced modelling results on the product variety. The incorporation of the personnel's preference into the decision-making can ensure that preferred products do not get eliminated by the decision-making framework. These are some ideas for possible future research.