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Sahoo SK, Sahoo HB, Priyadarshini D, Soundarya G, Rani KU. Antiulcer Activity of Ethanolic Extract of Salvadora indica ( W .) Leaves on Albino Rats. J Clin Diagnostic Res 2016; 10(9): 7-10.SahooSKSahooHBPriyadarshiniDSoundaryaGRaniKUAntiulcer Activity of Ethanolic Extract of Salvadora indica ( W .) Leaves on Albino RatsJ Clin Diagnostic Res201610971010.7860/JCDR/2016/20384.8470Search in Google Scholar
Zakaria ZA, Balan T, Suppaiah V, Ahmad S, Jamaludin F. Mechanism(s) of action involved in the gastroprotective activity of Muntingia calabura. J Ethnopharmacol 2014; 151(3): 1184-1193.10.1016/j.jep.2013.12.04524380736ZakariaZABalanTSuppaiahVAhmadSJamaludinFMechanism(s) of action involved in the gastroprotective activity of Muntingia calaburaJ Ethnopharmacol2014151311841193Open DOISearch in Google Scholar
Balan T, Mohd. Sani MH, Suppaiah V, Mohtarrudin N, Suhaili Z, Ahmad Z, et al. Antiulcer activity of Muntingia calabura leaves involves the modulation of endogenous nitric oxide and nonprotein sulfhydryl compounds. Pharm Biol 2014; 52(4): 410-418.10.3109/13880209.2013.839713BalanTMohdSani MHSuppaiahVMohtarrudinNSuhailiZAhmadZet alAntiulcer activity of Muntingia calabura leaves involves the modulation of endogenous nitric oxide and nonprotein sulfhydryl compoundsPharm Biol2014524410418Open DOISearch in Google Scholar
Boligon AA, de Freitas RB, de Brum TF, Waczuk EP, Klimaczewski CV, de Ávila DS, et al. Antiulcerogenic activity of Scutia buxifolia on gastric ulcers induced by ethanol in rats. Acta Pharm Sin B 2014; 4(5): 358-367.10.1016/j.apsb.2014.05.00126579405BoligonAAde FreitasRBde BrumTFWaczukEPKlimaczewskiCVde ÁvilaDSet alAntiulcerogenic activity of Scutia buxifolia on gastric ulcers induced by ethanol in ratsActa Pharm Sin B201445358367Open DOISearch in Google Scholar
Dubois RN, Abramson SB, Crofford L, Gupta RA, Simon LS, Van De Putte LBA, et al. Cyclooxygenase in biology and disease. FASEB J 1998; 12(12): 1063-1073.10.1096/fasebj.12.12.10639737710DuboisRNAbramsonSBCroffordLGuptaRASimonLSVanDe Putte LBAet alCyclooxygenase in biology and diseaseFASEB J1998121210631073Open DOISearch in Google Scholar
Miller TA. Protective effects of prostaglandins against gastric mucosal damage: current knowledge and proposed mechanisms. Am J Physiol Liver Physiol 1983; 245(5): G601-G623.MillerTAProtective effects of prostaglandins against gastric mucosal damage: current knowledge and proposed mechanismsAm J Physiol Liver Physiol19832455G601G62310.1152/ajpgi.1983.245.5.G601Search in Google Scholar
Miller TA. Mechanisms of stree-related mucosal damage. Am J Med 1987.MillerTAMechanisms of stree-related mucosal damageAm J Med198710.1016/0002-9343(87)90805-9Search in Google Scholar
Robert A. Cytoprotection by Prostaglandins. Gastroenterology 1979; 77: 761-767.10.1016/0016-5085(79)90235-X38173RobertACytoprotection by ProstaglandinsGastroenterology197977761767Open DOISearch in Google Scholar
Wallace JL, Keenan CM, Granger DN. Gastric ulceration induced by nonsteroidal anti-inflammatory drugs is a neutrophil-dependent process. Am J Physiol Liver Physiol 1990; 259(3): G462-G467.WallaceJLKeenanCMGrangerDNGastric ulceration induced by nonsteroidal anti-inflammatory drugs is a neutrophil-dependent processAm J Physiol Liver Physiol19902593G462G46710.1152/ajpgi.1990.259.3.G4622169206Search in Google Scholar
Pradeepkumar B, Bhavyamadhuri CP, Padmanabhareddy Y, Veerabhadrappa K V., Narayana G, Haranath C, et al. Evaluation of antiulcer activity of Peltophorum pterocarpum. J Clin Diagnostic Res 2017; 11(6): FF01-FF03.PradeepkumarBBhavyamadhuriCPPadmanabhareddyYVeerabhadrappaK V.NarayanaGHaranathCet alEvaluation of antiulcer activity of Peltophorum pterocarpumJ Clin Diagnostic Res2017116FF01FF0310.7860/JCDR/2017/26171.9998553538528764192Search in Google Scholar
Amang PA, Tan P V, Patamaken SA, Mefe MN. Cytoprotective and antioxidant effects of the methanol extract of Eremomastax speciosa in rats. African J Tradit Complement Altern Med 2014; 11(1): 165-171.AmangPATanP VPatamakenSAMefeMNCytoprotective and antioxidant effects of the methanol extract of Eremomastax speciosa in ratsAfrican J Tradit Complement Altern Med201411116517110.4314/ajtcam.v11i1.26395726024653572Search in Google Scholar
André Perfusion A, Tan P V, Ernestine N, Barthélemy N. Antisecretory action of the extract of the aerial parts of Eremomastax speciosa (Acanthaceae) occurs through antihistaminic and anticholinergic pathways. Adv Pharmacol Sci 2014; 2014. doi:10.1155/2014/323470.24695819André PerfusionATanP VErnestineNBarthélemyNAntisecretory action of the extract of the aerial parts of Eremomastax speciosa (Acanthaceae) occurs through antihistaminic and anticholinergic pathwaysAdv Pharmacol Sci20142014. doi10.1155/2014/323470395065824695819Search in Google Scholar
Idu EJO, Udo FO. Ethnomedicinal Survey of Medicinal Plants Used in the Treatment of Male Infertilty among the IFA Nkari People of Ini Local Government Area of. Res J Recent Sci 2013; 2(ISC-2012): 5-11.IduEJOUdoFOEthnomedicinal Survey of Medicinal Plants Used in the Treatment of Male Infertilty among the IFA Nkari People of Ini Local Government Area ofRes J Recent Sci20132ISC-2012511Search in Google Scholar
Udofia SI, Owoh PW, Ukpong EE, Ekpo IE. Assessment of plant species of socio- economic importance conserved in homegardens of Nsit Ubium local government area of Akwa Ibom State, Nigeria. Niger J Agric Food Environ 2012; 8(1): 99-108.UdofiaSIOwohPWUkpongEEEkpoIEAssessment of plant species of socio- economic importance conserved in homegardens of Nsit Ubium local government area of Akwa Ibom State, NigeriaNiger J Agric Food Environ20128199108Search in Google Scholar
Sagnia B, Fedeli D, Casetti R, Montesano C, Falcioni G, Colizzi V. Antioxidant and anti-inflammatory activities of extracts from Cassia alata, Eleusine indica, Eremomastax speciosa, Carica papaya and Polyscias fulva medicinal plants collected in Cameroon. PLoS One 2014; 9(8): e103999.2509061310.1371/journal.pone.0103999SagniaBFedeliDCasettiRMontesanoCFalcioniGColizziVAntioxidant and anti-inflammatory activities of extracts from Cassia alata, Eleusine indica, Eremomastax speciosa, Carica papaya and Polyscias fulva medicinal plants collected in CameroonPLoS One201498e103999412120025090613Search in Google Scholar
Okokon JE, Antia BS, Udoh AE, Akpan MM. Antianaemic and antimicrobial activity of Eremomastax speciosa. J Pharmacol Toxicol 2007; 2: 196-199.10.3923/jpt.2007.196.199OkokonJEAntiaBSUdohAEAkpanMMAntianaemic and antimicrobial activity of Eremomastax speciosaJ Pharmacol Toxicol20072196199Open DOISearch in Google Scholar
Oben JE, Assi SE, Agbor GA, Musoro DF. Effect of Eremomastax speciosa on experimental diarrhoea. African J Tradit Complement Altern Med 2006; 3(1): 95-100.ObenJEAssiSEAgborGAMusoroDFEffect of Eremomastax speciosa on experimental diarrhoeaAfrican J Tradit Complement Altern Med20063195100Search in Google Scholar
Onoja SO, Eke C, Ejiofor E, Madubuike KG, Ezeja MI, Omeh YN, et al. antioxidant, anti-inflammatory and anti-nociceptive properties of hydro-methanol extract of Eremomastax speciosa (HOCHST.) CUFOD leaf. African J Tradit Complement Altern Med 2017; 14(6): 56-63.10.21010/ajtcam.v14i6.6OnojaSOEkeCEjioforEMadubuikeKGEzejaMIOmehYNet alantioxidant, anti-inflammatory and anti-nociceptive properties of hydro-methanol extract of Eremomastax speciosa (HOCHST.) CUFOD leafAfrican J Tradit Complement Altern Med20171465663Open DOISearch in Google Scholar
National Research Council. Guide for the care and use of laboratory animals. National Academies Press; 2010, http://www.nap.edu/catalog/12910.htmlNational Research CouncilGuide for the care and use of laboratory animalsNational Academies Press2010http://www.nap.edu/catalog/12910.htmlSearch in Google Scholar
Inas AZA, Hala KAH, Heeba HG. Gastroprotective effect of Cordia Myxa L. fruit extract against indomethacin-induced gastric ulceration in rats. Life Sci J 2011; 8(3): 433-445.InasAZAHalaKAHHeebaHGGastroprotective effect of Cordia Myxa L. fruit extract against indomethacin-induced gastric ulceration in ratsLife Sci J201183433445Search in Google Scholar
Silva LP, De Angelis CD, Bonamin F, Kushima H, Jose MF, Dos Santos LC, et al. Terminalia catappa L.: A medicinal plant from the Caribbean pharmacopeia with anti-Helicobacter pylori and antiulcer action in experimental rodent models. J Ethnopharmacol 2015; 159: 285-295.10.1016/j.jep.2014.11.025SilvaLPDe AngelisCDBonaminFKushimaHJoseMFDosSantos LCet alTerminalia catappa L.: A medicinal plant from the Caribbean pharmacopeia with anti-Helicobacter pylori and antiulcer action in experimental rodent modelsJ Ethnopharmacol201515928529525460589Open DOISearch in Google Scholar
Shay H, Komarov S, Fels S, Meranze D, Gruenstein M, Siplet H. A simple method for the uniform production of gastric ulceration in rat. Gastroenterology 1945; 5: 43-61.ShayHKomarovSFelsSMeranzeDGruensteinMSipletHA simple method for the uniform production of gastric ulceration in ratGastroenterology194554361Search in Google Scholar
Sharma P, Prakash T, Kotresha D, Ansari MA, Sahrm UR, Kumar B, et al. Antiulcerogenic activity of Terminalia chebula fruit in experimentally induced ulcer in rats. Pharm Biol 2011; 49(3): 262-268.2132347810.3109/13880209.2010.503709SharmaPPrakashTKotreshaDAnsariMASahrmURKumarBet alAntiulcerogenic activity of Terminalia chebula fruit in experimentally induced ulcer in ratsPharm Biol201149326226821323478Search in Google Scholar
Ijioma SN, Nwosu CO, Onyenegecha C. Anticholinergic property of ethanol extract of Moringa oleifera Leaves: An in vivo and in vitro approach. J Clin Exp Res 2014; 2(2): 133-137.10.5455/jcer.201426IjiomaSNNwosuCOOnyenegechaCAnticholinergic property of ethanol extract of Moringa oleifera Leaves: An in vivo and in vitro approachJ Clin Exp Res201422133137Open DOISearch in Google Scholar
Hiruma-Lima CA, Calvo TR, Rodrigues CM, Andrade FDP, Vilegas W, Brito ARMS. Antiulcerogenic activity of Alchornea castaneaefolia effects on somatostatin, gastrin and prostaglandin. J Ethnopharmacol 2006; 104(1): 215-224.10.1016/j.jep.2005.09.00716253451Hiruma-LimaCACalvoTRRodriguesCMAndradeFDPVilegasWBritoARMSAntiulcerogenic activity of Alchornea castaneaefolia effects on somatostatin, gastrin and prostaglandinJ Ethnopharmacol2006104121522416253451Open DOISearch in Google Scholar
Al Batran R, Al-Bayaty F, Jamil Al-Obaidi MM, Abdualkader AM, Hadi HA, Ali HM, et al. In Vivo Antioxidant and Antiulcer Activity of Parkia speciosa Ethanolic Leaf Extract against Ethanol-Induced Gastric Ulcer in Rats. PLoS One 2013; 8(5): 2-12.AlBatran RAl-BayatyFJamilAl-Obaidi MMAbdualkaderAMHadiHAAliHMet alIn Vivo Antioxidant and Antiulcer Activity of Parkia speciosa Ethanolic Leaf Extract against Ethanol-Induced Gastric Ulcer in RatsPLoS One20138521210.1371/journal.pone.0064751366581323724090Search in Google Scholar
Yang X, Zhang X, Yang SP, Le T, Chen B. Evaluation of Aucklandia lappa Decne extracts as antiulcer activity in animals. Pak J Pharm Sci 2016; 29(5): 1695-1701.27731831YangXZhangXYangSPLeTChenBEvaluation of Aucklandia lappa Decne extracts as antiulcer activity in animalsPak J Pharm Sci201629516951701Search in Google Scholar
Sabiu S, Garuba T, Sunmonu TO, Sulyman AO, Ismail NO. Indomethacin-induced gastric ulceration in rats: Ameliorative roles of Spondias mombin and Ficus exasperataToxicol Reports 2015; 2(0): 261-267.10.1016/j.toxrep.2015.01.002SabiuSGarubaTSunmonuTOSulymanAOIsmailNOIndomethacin-induced gastric ulceration in rats: Ameliorative roles of Spondias mombin and Ficus exasperataToxicol Reports201520261267Open DOISearch in Google Scholar
Shokunbi OS, Odetola AA. Gastroprotective and antioxidant activities of Phyllanthus amarus extracts on absolute ethanolinduced ulcer in albino rats. J Med Plants Res 2015; 2(10): 261-267.ShokunbiOSOdetolaAAGastroprotective and antioxidant activities of Phyllanthus amarus extracts on absolute ethanolinduced ulcer in albino ratsJ Med Plants Res2015210261267Search in Google Scholar
Tamboli F, More H. Evaluation of antiulcer and antioxidant activity of Barleria gibsoni Dalz. leaves. Pharmacognosy Res 2016; 8(4): 226.10.4103/0974-8490.18887927695259TamboliFMoreHEvaluation of antiulcer and antioxidant activity of Barleria gibsoni Dalz. leavesPharmacognosy Res201684226Open DOISearch in Google Scholar
Zabidi Z, Wan Zainulddin WN, Mamat SS, Shamsahal Din S, Kamisan FH, Yahya F, et al. Antiulcer activity of methanol extract of Melastoma malabathricum leaves in rats. Med Princ Pract 2012; 21(5): 501-503.2251729610.1159/000337406ZabidiZWanZainulddin WNMamatSSShamsahalDin SKamisanFHYahyaFet alAntiulcer activity of methanol extract of Melastoma malabathricum leaves in ratsMed Princ Pract2012215501503Search in Google Scholar
Jorge RM, Leite JP V, Oliveira AB, Tagliati CA. Evaluation of antinociceptive, anti-inflammatory and antiulcerogenic activities of Maytenus ilicifoliaJ Ethnopharmacol 2004; 94(1): 93-100.1526196810.1016/j.jep.2004.04.019JorgeRMLeiteJP VOliveiraABTagliatiCAEvaluation of antinociceptive, anti-inflammatory and antiulcerogenic activities of Maytenus ilicifoliaJ Ethnopharmacol200494193100Search in Google Scholar
Lima DKS, Ballico LJ, Lapa FR, Gonçalves HP, de Souza LM, Iacomini M, et al. Evaluation of the antinociceptive, anti-inflammatory and gastric antiulcer activities of the essential oil from Piper aleyreanum C. DC in rodents. J Ethnopharmacol 2012; 142(1): 274-282.10.1016/j.jep.2012.05.016LimaDKSBallicoLJLapaFRGonçalvesHPde SouzaLMIacominiMet alEvaluation of the antinociceptive, anti-inflammatory and gastric antiulcer activities of the essential oil from Piper aleyreanum CDC in rodents. J Ethnopharmacol20121421274282Open DOISearch in Google Scholar
Rang HP, Dale MM, Ritter JM, Moore PK. Pharmacology (5th edn). Churchill Livingstone Edinburgh 2007.RangHPDaleMMRitterJMMoorePKPharmacology (5th edn)Churchill LivingstoneEdinburgh2007Search in Google Scholar
Allen A, Flemström G. Gastroduodenal mucus bicarbonate barrier: protection against acid and pepsin. Am J Physiol Physiol 2005; 288(1): C1-C19.10.1152/ajpcell.00102.2004AllenAFlemströmGGastroduodenal mucus bicarbonate barrier: protection against acid and pepsinAm J Physiol Physiol20052881C1C19Open DOISearch in Google Scholar
Schubert ML, Peura DA. Control of gastric acid secretion in health and disease. Gastroenterology 2008; 134(7): 1842-1860.1847424710.1053/j.gastro.2008.05.021SchubertMLPeuraDAControl of gastric acid secretion in health and diseaseGastroenterology2008134718421860Search in Google Scholar
Babu HT, Manjulatha K, Kumar SG, Hymavathi A, Tiwari AK, Purohit M, et al. Gastroprotective flavonoid constituents from Oroxylum indicum Vent. Bioorganic Med Chem Lett 2010; 20(1): 117-120.10.1016/j.bmcl.2009.11.024BabuHTManjulathaKKumarSGHymavathiATiwariAKPurohitMet alGastroprotective flavonoid constituents from Oroxylum indicum VentBioorganic Med Chem Lett2010201117120Open DOISearch in Google Scholar
Amang AP, Mezui C, Siwe GT, Emakoua J, Mbah G, Nkwengoua EZ, et al. Healing and antisecretory effects of aqueous extract of Eremomastax speciosa (Acanthaceae) on unhealed gastric ulcers. Biomed Res Int 2017. https://doi.org/10.1155/2017/1924320AmangAPMezuiCSiweGTEmakouaJMbahGNkwengouaEZet alHealing and antisecretory effects of aqueous extract of Eremomastax speciosa (Acanthaceae) on unhealed gastric ulcersBiomed Res Int2017https://doi.org/10.1155/2017/192432010.1155/2017/1924320Search in Google Scholar
Tan PV, Nditafon NG, Yewah MP, Dimo T, Ayafor FJ. Eremomastax speciosa effects of leaf aqueous extract on ulcer formation and gastric secretion in rats. J Ethnopharmacol 1996; 54: 139-142.10.1016/S0378-8741(96)01461-48953428TanPVNditafonNGYewahMPDimoTAyaforFJEremomastax speciosa effects of leaf aqueous extract on ulcer formation and gastric secretion in ratsJ Ethnopharmacol199654139142Open DOISearch in Google Scholar
Sofowora EA. Medicinal plants and traditional medicine in Africa. 3rd ed. Spectrum books Ltd: Nigeria 2008.SofoworaEAMedicinal plants and traditional medicine in Africa. 3rd edSpectrum books LtdNigeria2008Search in Google Scholar
