<abstract xmlns="http://www.w3.org/1999/xhtml"> The aims of this case-control study were to determine the prevalence of <italic><italic>Anisakis</italic></italic>-specific IgE in patients reporting chronic or acute gastrointestinal (GI) symptoms and to investigate the correlation with raw fish ingestion habits.A group of patients undergoing gastric endoscopy and a control group of healty subjects answered a self-administered questionnaire on their food habits, presence of symptoms (both allergic and not allergic), and general life style. The presence of anti-<italic>Anisakis</italic> IgE has been evaluated using a serum immunoCAP assay.Our data show a low prevalence of IgE directed against <italic>Anisakis</italic> allergens in Italy in dyspeptic patients, despite the high consumption of poorly cooked fish. These findings does not correlate with the results of studies from other Mediterranean countries, such as Spain, for example.The general prevalence of <italic>Anisakis</italic> allergens sensitization in Italy could be further investigated through screenings in the allergic population, especially on those patients who claim to have developed a fish allergy and with history of raw fish consumption. Moreover, the attention should be moved on recent allergic reactions associated with fishing ingestion. This could in fact indicate a recent encounter with the parasite. Finally, we must underline that the evaluation of <italic>Anisakis</italic>-specific IgG would have probably shown a difference in terms of exposure between the two groups; thus, it might be useful to detect also this antibody class in future population-based studies.</abstract>

The aims of this case-control study were to determine the prevalence of Anisakis-specific IgE in patients reporting chronic or acute gastrointestinal (GI) symptoms and to investigate the correlation with raw fish ingestion habits.A group of patients undergoing gastric endoscopy and a control group of healty subjects answered a self-administered questionnaire on their food habits, presence of symptoms (both allergic and not allergic), and general life style. The presence of anti-Anisakis IgE has been evaluated using a serum immunoCAP assay.Our data show a low prevalence of IgE directed against Anisakis allergens in Italy in dyspeptic patients, despite the high consumption of poorly cooked fish. These findings does not correlate with the results of studies from other Mediterranean countries, such as Spain, for example.The general prevalence of Anisakis allergens sensitization in Italy could be further investigated through screenings in the allergic population, especially on those patients who claim to have developed a fish allergy and with history of raw fish consumption. Moreover, the attention should be moved on recent allergic reactions associated with fishing ingestion. This could in fact indicate a recent encounter with the parasite. Finally, we must underline that the evaluation of Anisakis-specific IgG would have probably shown a difference in terms of exposure between the two groups; thus, it might be useful to detect also this antibody class in future population-based studies.

Low <italic>Anisakis</italic>-specific IgE prevalence in dyspeptic patients in Italy – a retrospective study

The EuroBiotech Journal

This work is licensed under the Creative Commons Attribution-NonCommercial-NoDerivatives 4.0 License.

Low -specific IgE prevalence in dyspeptic patients in Italy – a retrospective study

The aims of this case-control study were to determine the prevalence of Anisakis-specific IgE in patients reporting chronic or acute gastrointestinal (GI)...

Low Anisakis-specific IgE prevalence in dyspeptic patients in Italy – a retrospective study

Article Category: Research Article

Published Online: Feb 06, 2018

Page range: 59 - 63

DOI: https://doi.org/10.2478/ebtj-2018-0009

Keywords
food allergy, raw fish, sensitization

© 2018 Fabrizio Bruschi, Barbara Castagna, Francesca Mori-Ubaldini, Barbara Pinto, Francesco Costa, Ferruccio Bonino, published by Sciendo

This work is licensed under the Creative Commons Attribution-NonCommercial-NoDerivatives 4.0 License.

Low Anisakis-specific IgE prevalence in dyspeptic patients in Italy – a retrospective study

Article Category: Research Article

Published Online: Feb 06, 2018

Page range: 59 - 63

DOI: https://doi.org/10.2478/ebtj-2018-0009

Keywordsfood allergy, raw fish, sensitization

© 2018 Fabrizio Bruschi, Barbara Castagna, Francesca Mori-Ubaldini, Barbara Pinto, Francesco Costa, Ferruccio Bonino, published by Sciendo

This work is licensed under the Creative Commons Attribution-NonCommercial-NoDerivatives 4.0 License.

Keywords
food allergy, raw fish, sensitization