<abstract xmlns="http://www.w3.org/1999/xhtml"><p>There remains uncertainty about the rate of oxidation of nitric oxide (NO) in cigarette smoke. Using a single-port smoking machine and a chemiluminescence NO analyser we have investigated the rate of NO disappearance during cigarette smoke ageing over 10 minutes for gas phase and whole smoke. The disappearance of NO in whole smoke conformed to the (pseudo) second order kinetics observed for oxidation of NO in air. In the gas phase however the rate of disappearance was more rapid and appeared to follow first order kinetics. The possible mechanisms for this difference in behaviour are discussed.</p></abstract>

There remains uncertainty about the rate of oxidation of nitric oxide (NO) in cigarette smoke. Using a single-port smoking machine and a chemiluminescence NO analyser we have investigated the rate of NO disappearance during cigarette smoke ageing over 10 minutes for gas phase and whole smoke. The disappearance of NO in whole smoke conformed to the (pseudo) second order kinetics observed for oxidation of NO in air. In the gas phase however the rate of disappearance was more rapid and appeared to follow first order kinetics. The possible mechanisms for this difference in behaviour are discussed.

A Comparison between the Rate of Reaction of Nitric Oxide in the Gas Phase and in Whole Cigarette Smoke

Department of Respiratory Physiology, Addenbrooke's Hospital, Cambridge, England,

Department of Nuclear Medicine, Addenbrooke's Hospital, Cambridge, England,

Department of Physical Chemistry, University of Cambridge Chemical Laboratory, Cambridge, England

Contributions to Tobacco & Nicotine Research

This work is licensed under the Creative Commons Attribution-NonCommercial-NoDerivatives 3.0 License.

There remains uncertainty about the rate of oxidation of nitric oxide (NO) in cigarette smoke. Using a single-port smoking machine and a chemiluminescence NO...

A Comparison between the Rate of Reaction of Nitric Oxide in the Gas Phase and in Whole Cigarette Smoke

Published Online: Jan 06, 2015

Page range: 67 - 73

Received: Jul 26, 1984

Accepted: Mar 07, 1985

DOI: https://doi.org/10.2478/cttr-2013-0557

© 1985 Beiträge zur Tabakforschung International

This work is licensed under the Creative Commons Attribution-NonCommercial-NoDerivatives 3.0 License.